Systemic vasculitis - a very different diseases affecting different organs and different from manifesting symptoms. Nevertheless, they clearly share one attribute: the defeat of the walls of blood vessels, resulting in disturbed function of internal organs.
The main symptoms of systemic vasculitis
Despite the variety of individual forms of systemic vasculitis, they have a common clinical signs and symptoms. One of these features is the rise in temperature, the peaks of which comes at a time of fresh outbreaks of vascular lesions. At the same time almost all patients appear malaise, weakness, loss of appetite and body weight, a gradual depletion.
Common to all of systemic vasculitis are also skin-hemorrhagic and musculo-articular syndrome, and frequent involvement in the pathological process of the peripheral nervous system.
Skin-hemorrhagic syndrome, systemic vasculitis appears different kinds of hemorrhagic (bleeding a) rash, which is often accompanied by tissue necrosis, followed by the formation of ulcers. Muscle and joint pain syndrome occurs in muscles, joints, and inflammation of the joints.
Pathological processes in the peripheral nervous system manifest neuritis and polyneuritis. Internal organ involvement characterized by multiple and manifest stroke, angina and myocardial infarction, renal, lung (with the development of bronchospasm), liver, spleen, gastrointestinal tract, eyes, and so on.
The disease is mainly long-term, progressive or recurrent (with frequent exacerbations).
Symptoms of temporal giant cell arteritis
When the disease affects the large vessels that carry blood to the skull and brain - carotid, temporal, of vertebrates. Disease begins acutely, with fever, headache, muscle pain, weakness, malaise, pain when chewing. Headache often localized in the temporal region, but may extend to the temporal and parietal region. She has a burning, throbbing character and worse at night. There are also heightened sensitivity and swelling of the skin in the temporal region.
On the scalp nodules appear, artery dense and painful at a palpation on the affected side may be no pulse. It affects eyesight: reduced visual acuity, there is double vision, can develop blindness. Often develop paralysis of the cranial nerves, especially the oculomotor palsy often develop. It is also possible lesions of the brain stem and cerebellum, as well as the organ of hearing with the development of a full or partial deafness.
Rapid detection of disease and the appointment of adequate treatment lead to regression of symptoms of transient visual disturbances. But if there was complete blindness, these changes are usually irreversible.
Symptoms periarteritis nodosa
This disease affects the small and medium-sized blood vessels of the kidneys, heart, gastrointestinal tract, pancreas, liver, skeletal muscle, the peripheral nervous system, the testes. There inflammatory infiltration of all layers of vascular walls to form nodules and small blood vessels to dilate.
Persistent disease manifested fever, exhaustion, pain in muscles and joints, neuritis and polyneuritis. Because of circulatory disorders can appear foci of necrosis (necrosis) in the kidneys (in violation of the functions of this body, the development of malignant hypertension, and glomerulonephritis), heart (myocardial infarction), gastrointestinal tract (with the formation of ulcers).
In the interior of the pancreas
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and the spleen may appear hematoma (blood) due to violation of the integrity of the vascular wall. Most dangerous is thrombosis
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mesenteric arteries that carry blood to the intestines. This leads to necrosis of the intestinal wall, perforation and peritonitis.
The disease most often acute, subacute but occurs continuously or frequently relapsing progressive. The timely appointment of adequate treatment can stop the progression of the disease process.
Identify systemic vasculitis
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sometimes can not afford even the doctor as the disease is rare. Treat it as difficult and certainly not worth doing it yourself. If you suspect a systemic vasculitis
Systemic vasculitis: the disease may be different
should seek help from a rheumatologist - the specialist knows how to manifest systemic vasculitis that needs to be done to confirm the diagnosis and how to treat the patient.