Citramon P - why is it so effective? - About drugs

What Constitutes tsitramona II and how it works

Citramon - a combination product, which originally consisted of: atsitilsalitsilovaya acid (aspirin), phenacetin and caffeine. But due to the fact that phenacetin has many undesirable side effects (especially on the kidneys and liver), he was taken out of production and replaced in tsitramon entered paracetamol, and the drug was called tsitramon P.

Citramon P - is the combined analgesic and antipyretic action which determines its constituent drugs:

• acetylsalicylic acid (aspirin) - nonsteroidal anti-inflammatory drugs (NSAIDs), anti-inflammatory, antipyretic, analgesic and prevents blood clots action; However, there are a number of negative properties: it means vysokoallergennoe strongly irritates the mucous membranes of the gastrointestinal tract;
• acetaminophen - a pain reliever and fever reducer, belonging to the same series as the phenacetin removed from production, but with fewer side effects; However, with prolonged use, particularly at high doses, it can have toxic effects on the kidneys and liver;
• Caffeine - a stimulant of mental activity has a strong stimulating effect on the central nervous system, reduces fatigue and drowsiness; in large doses resulting in the depletion of neural cells; under the influence of caffeine quickens breathing and heart, thereby increasing blood pressure (BP), but also the expansion of the blood vessels in skeletal muscle, heart and kidney smooth out this effect and, in general significant rise in blood pressure is not observed; blood vessels of the abdomen and brain are narrowed, especially when their long-term expansion - which is why caffeine helps with migraine attack is accompanied by a sharp expansion of the blood vessels of the brain; headache Caffeine increases the effects of painkillers.

All are part of tsitramona II drugs mutually reinforce each other's action.

Indications and contraindications for use

Citramon take:

• as a pain reliever with moderately severe pain: headache, migraine (headaches in one half of the head), toothache Toothache - itself does not take place , Pain along the nerve, joint and muscle pain, painful menstruation;
• as an antipyretic at high temperatures accompanying colds and infectious diseases;
• as a mild anti-inflammatory rheumatic diseases.

Contraindications tsitramona:

• gastric ulcer and duodenal ulcer;
• gastrointestinal bleeding (including the last);
• abnormal liver function or kidney (this is especially true for older people who rarely are examined and have no information on the state of the organism);
• uric acid metabolism disorders - gout;
• blood clotting problems, increased bleeding;
• Before surgery - enhanced tendency to bleeding;
• a genetic deficiency of glucose-6-phosphate dehydrogenase (enzymatic deficiency causing anemia);
• increased intraocular pressure (glaucoma);
• hypersensitivity to the drug, "Aspirin" asthma (appearance attacks bronchospasm in aspirin);
• pregnancy (especially the first 12 weeks), lactation Breast-feeding: feed - and no nails! ;
• age up to 15 years.

Do not take tsitramon n 5 consecutive days as an analgesic and 3 days - as antipyretic without consulting a doctor.

At the reception tsitramona U should refrain from drinking alcohol. Do not use it simultaneously with drugs and anticonvulsants, salicylates and rifampicin. Citramon P enhances the effect of drugs, possessing protivotrombaticheskim and antidiabetic effects.

Side effects that may occur while taking tsitramona II and his overdose

When receiving tsitramona II, the following side effects: indigestion, nausea, abdominal pain Abdominal pain: Types and Symptoms , Erosive and ulcerative lesions of the mucous membrane of the gastrointestinal tract, including hours bleeding complications, hepatic dysfunction, dizziness, palpitations, increased bleeding, allergic reactions such as urticaria, bronchospasm (asthma attacks).

In overdose tsitramona appear stomach pain, nausea, vomiting, sweating, pale skin, rapid heartbeat. First aid: gastric lavage and administration of activated charcoal Activated carbon - old but indispensable .