Flucostat during pregnancy - whether it is not dangerous?

September 9, 2011

 fljukostat during pregnancy
 Thrush - one of the main problems during pregnancy. Should I treat it? Obstetricians believe that not only costs, but also necessary in order not to infect the baby. But the problem is that not everyone is an antifungal medication fit a pregnant woman.

 Flucostat during pregnancy - whether it is not dangerous?

The problem of thrush during pregnancy

Thrush is caused by yeast fungi of the genus Candida. In most people these fungi are present in the mucosa of the genital organs, but do not cause disease, because the body's defenses (immune system) do not allow them to penetrate the barrier such as the mucosa. The signs of thrush usually appear at lower immunity.

During pregnancy, the immune system is reduced - is the physiological response to the foreign cells of the fetus, which develops in the mother's body. If there was no decrease in immunity, then the mother ottorgnul to the fetus.

Immunosuppression is in addition to the advantages and disadvantages: in a woman's body begin to implement various pathogens, including fungi. Therefore, pregnant women often appear unpleasant symptoms such as burning, itching, cheesy white discharge - this is a sign of thrush or vulvovaginal candidiasis.

Yeasts isolated in 70-80% of pregnant women. Infection of the fetus mushrooms in utero is rare, however, such cases are the development of the fetus generalized (affecting all organs and systems) fungal infection and premature termination of pregnancy. There are also infected infants during childbirth. Therefore, fungal infections in pregnant women, be sure to treat.

 Flucostat during pregnancy - whether it is not dangerous?

What Flucostat and whether it can be applied to pregnant

Flucostat (INN - fluconazole) - is an antifungal medication wide spectrum of action. Its mechanism of action is based on the inhibition of synthesis of biologically active substances (ergosterol), required for the construction of cell walls, which leads to the death of fungi. The drug is very effective, it is active against most pathogenic fungi. Such a preparation can not have side effects. By fljukostat side effects include:

  • on the part of the gastrointestinal tract - a violation of appetite, nausea, vomiting, diarrhea, abdominal pain Abdominal pain: Types and Symptoms  Abdominal pain: Types and Symptoms
 , Bloating, transient liver function abnormalities, including severe;
  • the central nervous system - headache, dizziness Dizziness - if the ground is slipping from under his feet  Dizziness - if the ground is slipping from under his feet
 , Susceptibility to seizures;
  • from the blood - decrease in the number of white blood cells, including granulosa (sharp decline in immunity), decreased platelet count (tendency to bleed);
  • the part of the circulatory system: cardiac arrhythmia;
  • allergic reactions - immediate (urticaria, angioedema, anaphylactic shock) and slow (for example, skin rash) type;
  • by metabolic processes - increased blood levels of bad cholesterol clogging blood vessels, reduction in blood potassium ions (which are particularly necessary for the working of the heart muscle).
  • Other side effects - renal dysfunction, baldness.

Even if you just read the list of side effects, it becomes quite clear that prescribe such a drug for the treatment of thrush Treating Thrush: how to get rid of bad fungus  Treating Thrush: how to get rid of bad fungus
   pregnant women is not necessary. In addition, there are no reliable studies on the effects on the developing fetus fljukostat. Furthermore, there are publications that it is teratogenic (causing malformation) and embryotoxic (capable of intoxicating affect the fetus) effect.

However, sometimes you have to take risks and to assign pregnant women Flucostat, but it is only when she developed generalized (involving all organs and systems) defeated body. This is just one classic case where the "expected benefit of treatment exceeds potential risk to the fetus" (the standard phrase used in the instructions for medications).

 Flucostat during pregnancy - whether it is not dangerous?

What can be taken by pregnant women with thrush?

When thrush are special drugs that are not absorbed into the blood and act only locally, without causing systemic effects on the body. These drugs include, for example, pimafutsin Pimafucin - help in difficult times  Pimafucin - help in difficult times
 , Gyno-pevaril, gyno-daktorin, Gyno-Lotrimin, gyno-daktanol, gyno-travogen. All these drugs are prescribed locally in the form of vaginal tablets or suppositories.

Flucostat during pregnancy can certainly be used, but only in extreme cases where fungal infection has spread so much that threatens the lives of women and children. And certainly this drug should not be used without a doctor's prescription.

Galina Romanenko

Article Tags:
  • fljukostat

Tsiprolet and pregnancy: not tested

October 26th, 2011

 Tsiprolet and pregnancy
 Tsiprolet not allowed to be used during pregnancy, despite the fact that it is quite safe drug, which rarely produce side effects. The reason for this prohibition is that in pregnant women were not conducted clinical trials tsiprolet Tsiprolet - prevents the growth of bacteria  Tsiprolet - prevents the growth of bacteria

 Tsiprolet and pregnancy: not tested

When and what antibiotics can be used for pregnant women

All drugs that are permitted to be used during pregnancy, should undergo laboratory and clinical trials. In fact, not all drugs are in clinical trials on pregnant. Therefore, in accordance with the danger for pregnant women all medicines are divided into groups:

  • Group A - the drug has passed all laboratory and clinical trials as a result of which was not revealed any adverse effects on the fetus at any stage of pregnancy; this group can not be attributed any one drug as any drug has side effects;
  • Group B - were conducted laboratory tests on animals, which resulted showed no adverse effects on the fetus; clinical trials (in pregnant women) were not carried out;
  • Group C - the tests on animals have revealed adverse effects on the fetus; clinical trials have not been conducted, but the intended benefits of its reception may justify the potential risk;
  • Group D - from research and practical applications of the drug were identified and proven adverse effect of the drug on the human fetus, but the expected benefits from its reception may justify the risk;
  • Group E - the use in pregnant women unfairly. The risk for the fetus is greater than the possible benefit to the mother.

Particular care must be directed to the use of antibiotics during pregnancy. Dangerous antibiotics in the first 12 weeks of pregnancy when there is a bookmark of the internal organs. But since the final terms of bookmarks unknown and in most cases they are individual for each woman, is considered safe antibiotics after the twenty-second week of pregnancy.

The most studied and safely used in these terms Antibiotics penicillin and cephalosporins. But even these apply safest antibiotics is necessary only after a doctor's prescription.

 Tsiprolet and pregnancy: not tested

As tsiprolet studied the effect on the body of pregnant women

Tsiprolet was only laboratory tests on animals. As a result of these studies it was found that any adverse effect on fertility (fertility) or teratogennoogo effects on the fetus (teratogenicity - is the ability to cause malformations in the fetus) tsiprolet has not. In the animal experiments are assigned dose tsiprolet six times the usual daily dose of man. But this animal. Data also how tsiprolet effect on pregnant women, not, as clinical studies have not been conducted.

Tsiprolet not approved for use in pregnant women, children and adolescents also because in some cases it causes arthropathy - destruction of the joints, which are accompanied by pain and sometimes even torn ligaments. Such action tsiprolet been identified in laboratory animals - arthropathy occurs primarily in young animals.

The side effects tsiprolet also includes such symptoms as pain in the joints Joint pain - how to understand what is going on?  Joint pain - how to understand what is going on?
 , Muscle and ligament rupture. Therefore tsiprolet not recommended for use in the treatment of growing organisms.

 Tsiprolet and pregnancy: not tested

What about pregnant women who need to use antibiotics

Indeed, in some cases, pregnant women requiring such treatment. This is often necessary in order to prevent the occurrence of intrauterine infection of the fetus, if any infection of the genital organs have a mother. Prescribe antibiotics and infectious and inflammatory diseases of various organs, such as pyelonephritis Pyelonephritis - kidney disease  Pyelonephritis - kidney disease

In this case, the use of antibiotics is necessary and high risk taking in their purpose and under medical supervision there. Doctors obstetricians and internists antenatal knows what antibiotics and at what stage of pregnancy you can assign. Another thing, if a woman chooses to be treated with antibiotics Antibiotics - whether they will help you in the foreseeable future?  Antibiotics - whether they will help you in the foreseeable future?
   self - the risk of such treatment is too high, because only rely on the instructions that have developed drug manufacturers not worth it. Firstly, they are written for doctors and people without medical training can not always understand them, and secondly, in addition to the instructions of doctors have special benefits and guidelines clarifying certain issues on the treatment of pregnant women.

A pregnant woman is a single pill can not take without a prescription!

Galina Romanenko

Article Tags:
  • tsiprolet