Sirdalud - a drug that helps to relieve spasms of skeletal muscles. These cramps are always accompanied by diseases of the spine and large joints, sometimes they themselves are always painful and increase the pain caused by the underlying disease.
Features sirdalud action on the body
Sirdalud is a centrally acting muscle relaxant, meaning it relaxes the skeletal muscles. The mechanism of action sirdalud associated with decreased release of nerve cells (neurons) neurotransmitter amino acids (e.g., glutamic acid), which stimulate the transmission of nerve excitation in the synapses of the central nervous system, in particular in the synapses located in the spinal cord. Synapse called the place of transition from one nerve cell to another, which is transmitted through the nervous excitement with special chemicals called neurotransmitters. Pulses of nervous excitement not reach the skeletal muscles and the muscles relax. Sirdalud has also some analgesic activity which is enhanced by the combined treatment with analgesics.
Sirdalud is rapidly and almost completely absorbed when administered in the intestine and enters the bloodstream. Maximum concentration in blood reached after 1 - 2 hours, it acts on average for 6 hours. Sirdalud decomposed in the liver into inactive components and then output mainly in the urine.
Suitable sirdalud as acute sudden spasm of skeletal muscles, and at long spastic conditions caused by chronic neurological diseases. At this dose the patient his physician individually selected and can be gradually increased significantly compared to the conventional therapeutic dose. It should be borne in mind that high doses of the drug increases the risk of side effects.
Which diseases appoint sirdalud
Sirdalud is assigned at any diseases of the spine and joints, which are accompanied by a spasm of skeletal muscles. This spasm is a reflex - so the body protects the painful area of the injury. But the spasm of pain increases and promotes the formation of abnormal movements or severely restricts the movement. After removing the painful spasms of skeletal muscles the patient's condition improved significantly. Especially effective centrally acting muscle relaxants in the complex treatment of neurological patients.
Apply sirdalud with sudden acute lumbago, when there is compression of the spinal nerves. In this case, the removal of muscle spasm contributes to the partial withdrawal of infringement and reduce pain. Good help sirdalud at the cervical and lumbar syndrome.
In chronic neurological diseases that are accompanied by prolonged muscle spasms, such as multiple sclerosis
Multiple sclerosis - whether in remission?
, Cerebral palsy, sirdalud also able to improve the state of partially removing the muscle spasm. This reduces pain and allows the patient to produce some of passive and active motion.
Protective muscle spasm usually occurs after operations on the spine and large joints (eg, hip). In this case, the removal of muscle spasms in the background sirdalud promotes more rapid recovery of body functions after surgery.
This is contraindicated sirdalud
Sirdalud not indicated for children, as there is no experience of using this drug in children. You can not assign sirdalud women who breastfeed, as some of it is excreted in milk and may have a negative effect on the child's body. Not applicable sirdalud with severe liver disease in violation of their function - in this case, the drug can not completely degraded in the liver. Contraindications: Hypersensitivity of the components and sirdalud.
Not worth the risk and apply sirdalud with severe kidney disease in violation of their function - in this case, the drug appears very slowly and may come his overdose. If necessary, sirdalud given to patients with kidney disease in specially selected doses.
When pregnancy sirdalud prescribed only when absolutely necessary, as clinical trials in pregnant women were not conducted. But in animal studies adverse effects on the fetus have been identified.
Negative side effects sirdalud
Sirdalud can produce negative side effects such as nausea, vomiting, dizziness,
Dizziness - if the ground is slipping from under his feet
, Hallucinations, lethargy, weakness, sleep disturbances
Dreams: how to understand our dreams
and concentration, abnormal liver function, lower blood pressure
Blood pressure - dangerous if his swing?
. When such side effects the doctor individually decides to cancel the drug yl continue taking it.
Sirdalud and may cause an overdose, which manifests itself by a sharp increase side effects. Suspected overdose requires emergency medical activities, so you need to call an ambulance.