Asparkam is a drug that is widely used in the treatment of various diseases. An overdose of pills asparkama usually not dangerous, but his intravenous should be made with great caution and only on prescription.

In what diseases and conditions shall be appointed asparkam

The structure asparkama are salts of potassium and magnesium, which are essential for the proper operation of the cells of the heart muscle (myocardium). Therefore asparkam appointed in many heart diseases.

Asparkam also able to positively influence the metabolism in the myocardial cells, so it should apply in the case where these processes are disturbed - at ischemic heart disease (angina, myocardial infarction), congestive heart failure Heart failure - when the heart is unable to cope with the work   (ie violation of myocardial contractility) myocardial (metabolic disorders Metabolism: The basis of life of all living things   in myocardial cells) and so on.

Applied asparkam and if the blood contains an insufficient amount of potassium or magnesium. This happens in various diseases and conditions involving fluid loss (diarrhea, vomiting, dehydration when overheating, and so on), while taking laxatives and diuretics that remove potassium (furosemide) and so on.

But most often asparkam used in conjunction with cardiac glycosides - drugs that are prescribed for a long time, and sometimes in large doses. Cardiac glycosides slow the heart rate and can cause arrhythmia, asparkam prevents these complications.

When it is not recommended to take asparkam

Asparkam not take if heart block - a violation of cardiac conduction, as it slows the transmission of nerve impulses on the cardiac conduction system.

Another contraindication for use asparkama is the simultaneous use of drugs that contribute to the accumulation (savings) of potassium in the body. These properties are, for example, certain diuretics (triamterene, veroshpiron Veroshpiron - used with caution!   and so on).

With great care and only on prescription asparkam can be used in renal impairment - it contributes to the accumulation of potassium in the body, and this is very dangerous.

Not recommended the appointment of asparkama well as severe muscle weakness - it could worsen. Of course, asparkam can not be used and if it was an allergic reaction (if you are hypersensitive).

Complications at reception

Sometimes there are slight nausea (vomiting is very rare), diarrhea, discomfort and mild pain in the abdomen. But it passes quickly.

Danger intravenous asparkama especially fast, which may result in overdose. Symptoms of overdose: thirst, swelling and redness of the face, lower blood pressure, respiratory failure, convulsions and coma. Output from this state can only be entered if antagonists of potassium - solutions containing sodium and calcium salts.

While the use of antiarrhythmics enhanced ability to reduce conductivity and excitability of heart muscle. At simultaneous reception asparkama and certain medications (beta blockers, cyclosporine, ACE inhibitors, nonsteroidal anti-inflammatory drugs, potassium-sparing diuretics, salt substitutes cookbook containing potassium) increase the risk of hyperkalemia - high content of potassium in the blood.

How to apply

Asparkam tablets for the treatment of adults is assigned one or two tablets (dose adjusted individually) three times a day for at least three weeks (usually longer). Prophylactic dose is one tablet three times a day - courses taken for a month or longer. Children and pregnant women are the dosage and duration of treatment is chosen individually.

Intravenous asparkam (each vial contains 5 or 10 ml of the drug) is administered bolus or infusion, but in any case very slowly (possible overdose!) Dilution of its 5% glucose solution Glucose: The energy source . The dosage is selected individually depending on the patient's condition. Chip asparkam introduced at a rate of 5 ml per minute infusion - 25 drops per minute. Use only clear solutions and immediately after opening the ampoule. The solution asparkama not add any other medical solutions.

Asparkam tablets can be taken for a long time without fear of overdose, but intravenous administration should only be prescribed by a doctor.

Galina Romanenko

Diffuse changes of myocardium - is the conclusion of additional diagnostic tests as electrocardiography (ECG) and echocardiography (echocardiography - ultrasound of the heart). By itself, such a conclusion only says that the heart muscle (myocardium) have any changes that apply to the entire myocardium.

Which diseases can be diffuse changes in the myocardium

Diffuse changes in the heart muscle may occur mainly in myocardial inflammatory disease (myocarditis), the nature of the exchange (myocardiodystrophy) and as a result the development of connective tissue instead of the myocardial fibers, which is often the outcome of both inflammatory and metabolic diseases (myocardiosclerosis). Diffuse changes in the myocardium may also be caused by a violation of water-salt metabolism, heavy physical activity and the use of certain medications.

That is what is revealed in the survey as diffuse myocardial damage.

Diffuse changes of myocardium on an electrocardiogram and echocardiogram

With these additional methods like ECG echocardiogram can set different diffuse myocardial changes. These changes usually do not have any characteristics, which could be a definitive diagnosis (such as myocarditis or myocardial) so conclusion "Diffuse changes infarction" has a value only in combination with data from the survey and survey of the patient and additional studies (usually laboratory).

However, these studies are important because they allow us to separate diffuse myocardial changes by focal, which may be due to myocardial infarction Myocardial infarction - the most formidable diagnosis , Rheumatism Rheumatic fever - are possible complications of heart . ECG diffuse myocardial changes will be recorded in all leads while focal myocardial changes may be recorded in one - two leads. The ECG also shows arrhythmias, conduction, signs of hypertrophy (increase in volume) of the heart.

No less characteristic diffuse changes on echocardiogram, which are clearly visible changes in echogenicity (ultrasound reflection) across the myocardial tissue. Echocardiography may reveal enlargement (dilatation) of the various parts of the heart, myocardial hypertrophy, a violation of his motor activity, reduction of indirect signs of myocardial contractility.

Diffuse changes in the myocardium during myocarditis

Myocarditis - is an inflammatory disease of the myocardium. They can be contagious, infectious and toxic, allergic and toxic-allergic. Infectious and infectious-toxic myocarditis include, for example, myocarditis with influenza, scarlet fever Scarlet fever - threatening complications   and other infections. Allergic myocarditis may occur against the background of some chronic diseases, medication. Toxic-allergic myocarditis may occur when exposed to the body of various toxins in the body to which there is an allergy (alcoholic myocarditis, myocarditis, thyrotoxicosis - increased thyroid function).

Similar changes in echogenicity of myocardial tissue are noted and echocardiogram, which can detect the expansion of the various parts of the heart, a violation of the motor activity of the myocardium. In acute lesions of the heart muscle ECG changes in repeated studies allow time to grasp the severity of the process.

Diffuse changes in the myocardium during myocardial

Myocardiodystrophy - a condition which is a consequence of primary disorders of metabolic processes in the heart muscle (usually a violation of the biochemical reactions of formation and transformation of energy), which is accompanied by symptoms of deficiency of myocardial contractility.

Changes in the electrocardiogram and echocardiogram at myocardiodystrophy in most cases do not differ much from the changes in the myocarditis. Distinguish (differentiate), these diseases will be possible only after the laboratory tests: general blood test Complete blood count how to understand why taking blood from a finger   if myocarditis will change characteristic of the inflammatory process. In the biochemical analysis of blood it is often possible to see the changes that led to dystrophic changes in myocardium.

Thus, diffuse myocardial changes - this is only the conclusion of additional research methods, the final diagnosis is made only by a doctor on the basis of all the data.

Galina Romanenko