Panangin, indications for use - heart disease
June 10th, 2012
Active ingredient panangina are potassium aspartate and magnesium aspartate, which improve metabolism
Improves metabolism and losing weight without dieting
in cardiac muscle. Therefore Pananginum prescribed for heart failure, angina and myocardial infarction
Myocardial infarction - the most formidable diagnosis
, Heart rhythm disturbances. Necessarily it is administered and in the case where the patient receives cardiac glycosides.
Application panangina in coronary heart disease
Coronary heart disease (CHD) develops when atherosclerosis affects the coronary vessels of the heart. Atherosclerotic plaque deposited on the walls of blood vessels, thereby reducing their lumen. This leads to the fact that the slightest coronary vasospasm (as a result of physical or emotional stress) is disturbed blood supply to the heart muscle (myocardium), and with blood - the supply of nutrients and oxygen.
Potassium and magnesium ions are largely confined to the myocardial cells, they are as coenzymes (parts enzymes) involved in many biochemical reactions, including the synthesis of proteins required for cell and the delivery of energy from carbohydrates. Potassium deficiency leads to reduction of myocardial contractility, rhythm disturbances and heart rate. Magnesium deficiency also affects the strength and heart rate.
Such action panangina reduces myocardial oxygen demand, and hence during attacks of spasms of the coronary arteries myocardial cells affected to a lesser degree. This reduces the number and severity of attacks of angina pectoris and myocardial infarction is prevention. In addition, magnesium ions contribute to a decrease in contractility of the smooth muscle walls of the small arteries that supply the myocardium, causing them to expand and improve supply the heart muscle with blood.
Panangin necessarily indicated for coronary artery disease, unless, of course, to be received no contraindications.
Application panangina in chronic heart failure
Congestive heart failure is characterized by decreased myocardial contractility. The heart muscle can no longer with the same force to push blood in the blood vessels, which leads to stagnation, swelling in the legs, arms, all over the body, as well as in the lungs.
In order to make the myocardium to contract with greater force, the patient is prescribed drugs called cardiac glycosides. Under the influence of cardiac glycosides myocardium begins to decline less and with greater force. However, cardiac glycosides - are drugs that have many side effects, so it is very dangerous overdose.
One side effect of cardiac glycosides is the increase in the content of myocardial cells, sodium ions, and hence, reduced content of potassium ions, since these ions are generally located on opposite sides of the cell membranes. In order to reduce the toxic effect of cardiac glycosides, designate Pananginum: potassium ions enter the cells of the myocardium and reduce the toxic effect of cardiac glycosides. In addition, Pananginum in itself improves cardiac contractility, which can reduce the dose of cardiac glycosides.
Application panangina during cardiac arrhythmias
Cardiac arrhythmias can occur with a variety of diseases. At the same time a breach of the excitation pulses to the heart muscle is a violation of good coordination between the various cuts of myocardium, which leads to heart rhythm disturbances.
The slowdown or complete halting the spread of the excitation pulse to the heart is called the partial or complete blockade. When blockades some parts of the heart are reduced at their own pace, which leads to disruption of the entire circulatory system.
Pananginum case, restores the metabolism
Metabolism: The basis of life of all living things
in myocardial cells, which helps to improve the conductivity of cardiac pulses.
Application panangina to meet the shortfall of potassium and magnesium in reducing their content in foods
Potassium and magnesium are essential minerals that are ingested with food.
Adult daily requirement for magnesium is 400 mg for potassium - 2-3 g Magnesium is found in bananas
Bananas: the benefits and harms health
, Green leafy vegetables, sea fish and seafood (such as shrimp) nuts, whole grain bread. Potassium lot of dried apricots, raisins, baked potatoes, sunflower seeds, nuts (especially cedar), dairy products, liver.
Deficiency of magnesium and potassium negative impact on the whole body, but particularly affected heart muscle, so the eating disorders (except monotonous diet with foods rich in potassium and magnesium) is assigned Pananginum.
Unstable angina - alarm organism
October 6, 2014
For all forms of angina is characterized by pressing more or less severe chest pain
Chest pain is one symptom - a lot of diseases
It is localized usually in the sternum, and often radiating in shoulders, neck and hands. In unstable angina, this pain occurs suddenly, often - when the patient is at rest, and eventually seizures are becoming more severe. Sometimes unstable angina leads to a heart attack, so when the next attack symptoms should be as soon as possible to seek medical help.
The average age of patients with unstable angina is 62 years, but it can vary from 23 to 100 years. In women, it is the first time a violation is shown, usually at an older age than men. In addition, women have unstable angina often accompanied by disorders such as hypertension and diabetes
Diabetes - threatening and incurable disease
. The prognosis of this disease, apparently unrelated to the sex of the patient; it depends mainly on the degree of severity of the disorder.
The pathogenesis of unstable angina
The pathogenesis, or development of unstable angina for many years, remains a subject of debate among experts.
It has long been known that the stable and unstable angina develops in most cases due to narrowing of the lumen of the coronary artery associated with atherosclerosis. It is not known why for the same violation patency of the arteries in some patients develop stable, while others - unstable angina. In addition, a significant proportion of patients with unstable angina, coronary atherosclerosis absent.
It is assumed that sometimes unstable angina attacks may begin after severe or prolonged stress
How to beat stress? Create an oasis
or as a result of abuse of alcohol or tobacco, but if so, the nature of the attack is delayed reaction - it does not occur immediately after exposure to a trigger. In addition, there are cases when attacks occur in patients who lead a healthy lifestyle and do not suffer from severe stress.
Thus, unstable angina at the moment remains largely a mystery to researchers, as well as a great danger to patients as to predict its attacks virtually impossible.
The classification of unstable angina
Today, the diagnosis of unstable angina is used for classification of Braunwald:
It develops in the presence of extracardiac diseases that increase the expression of coronary heart disease (secondary unstable angina)
It develops in the absence of extracardiac disease (primary unstable angina)
It develops within two weeks after a heart attack (post-infarction angina)
Unstable angina, manifested itself for the first time, rest angina
Angina rest - invisible enemy
Angina at rest was in the last month, but not in the previous two days (subacute angina at rest)
Angina at rest was within the previous 48 hours (acute angina at rest)
The symptoms of unstable angina
The most typical symptoms of unstable angina:
- Pain or pressure in the chest;
- Profuse sweating even in the absence of physical activity;
- Sudden dizziness or weakness;
- Pain or pressure in the back, neck, jaw, abdomen, shoulders or arms.
Symptoms of this disorder often occur at rest, over time, attacks are becoming more frequent, heavy and prolonged. After taking nitroglycerin relief comes.
Diagnosis of unstable angina
During the first 24 hours after the attack, unstable angina recommended analysis on cardiac biomarkers, complete blood count (in particular, need to check the level of hemoglobin), as well as tests to determine the levels of electrolytes and blood lipids.
In addition, for diagnostic echocardiography, electrocardiography (ECG), coronary angiography. ECG can show unstable angina normal result, regardless of whether the survey is conducted at rest or during exercise, so that violations detection usually necessary to carry out a number of different diagnostic procedures, as well as the observation of the patient within a certain time.
Treatment of unstable angina
If signs of unstable angina should immediately call an ambulance. Patients with this disorder are hospitalized, and carried out a series of tests, which we discussed above. In addition, the doctor asks the patient in detail about his symptoms and medical history studies.
Since the effects of unstable angina attack are unpredictable, it is important as soon as possible to properly diagnose and determine whether sufficient medical treatment or surgical intervention is necessary.
In most cases, fortunately, medication is quite effective. To stabilize the condition of the patient and the further treatment can be used the following formulations:
- Aspirin. This drug is recommended to be given as soon as possible, ideally - for half an hour after the onset of symptoms of unstable angina attack. Patients who have had a bout is not the first time, as a rule, it is recommended to take aspirin without waiting for the arrival of doctors. A study of medical records of two thousand patients with unstable angina showed that aspirin reduces timely risk of myocardial infarction with the abuse on 11.8-6%. In the long-term risk may be reduced by 40-50%;
- Nitrates. Intravenous drugs from the class of nitrate can be used to relieve the symptoms of an attack of unstable angina;
- Clopidogrel. This antiplatelet drug from the class of thienopyridines may be given to patients who for any reason can not take aspirin. In addition, studies have shown that in combination with aspirin, clopidogrel allows achieving more substantial reduction in the risk of heart attack, but the risk of major bleeding becomes 3.7% above normal;
- Beta-blockers. In clinical trials, various beta-blockers has been found that their method allows to significantly reduce the frequency of attacks of unstable angina, alleviate their symptoms and reduce the likelihood of myocardial infarction. If an attack of unstable angina is associated with increased blood pressure, and / or it causes chest pain that persists for a long time, may be appointed as an intravenous infusion of beta-blockers. Patients with unstable angina may also need long-term use of these drugs - to prevent attacks in the future. Their effectiveness in such cases may depend on a number of factors such as the presence of concomitant cardiovascular and other diseases, lifestyle, use of other drugs, and so on.