- Jeanine - not only contraception but also protection against acne
- How does
- Side effects and contraindications
- During menopause
Janine - a low-dose combined oral contraceptive, which includes estrogen
Estrogen - the key to bone health
Absorption. After oral dienogest, one of the active substances in Janine is absorbed rapidly and completely. Its maximum concentration in serum is reached after about 2.5 hours, and is 52 ng / ml. Bioavailability ranges from 91% to 96%.
Distribution. Dienogest binds to the albumin contained in the blood. Approximately 90% of the molecules of the substance bound to albumin, and 10% of dienogest is in the blood in a free state.
Metabolism. Dienogest almost completely processed in the body; its clearance ranges from 3.4 to 3.7 l / h.
The half-life of dienogest - from 8.5 to 10.8 hours. A small amount of the substance in the unaltered state is excreted in urine and bile with a ratio of about 3 to 1.
Absorption. Ethinyl estradiol is absorbed completely and quickly. Its maximum concentration in the blood occurs within 1.5 - 4 hours after ingestion, and is about 67 ng / ml. Bioavailability ethinylestradiol is, on average, about 44%.
Distribution. Approximately 98% of ethinyl estradiol is bound to albumin. Ethinyl estradiol induces the synthesis of binding globulin sex hormone (SHBG).
Metabolism. Ethinylestradiol processed predominantly in the intestine and liver. His clearance is 2.3-7 ml / kg. It is excreted in the urine and bile in the ratio of approximately 4 to 6.
Jeanine contraceptive effect is provided by three complementary mechanisms:
- Suppression of ovulation
Ovulation - How to determine as accurately as possible?
at the level of the hypothalamic-pituitary regulation
- Change of properties of cervical secretions, resulting in disturbed sperm Activity
- Endometrial changes, which lead to the impossibility of implanting the fertilized egg
In women taking oral contraceptives, menstrual cycle becomes more regular, less often observed the pain during menstruation, bleeding profusely less, thereby reducing the risk of anemia
Anemia - when you do not have enough blood
- Iron deficiency.
The tablets should be taken orally, every day at the same time with a little water. When one package, which contains 21 tablets, is over, you need to do a seven-day break, during which menstrual bleeding usually begins. In most cases it takes 2-3 days after the last tablet. Start taking pills from a new package is necessary regardless of whether the bleeding is over or not.
How to start taking Jeanine
If in the previous month, you do not take any hormonal contraceptives, should start taking these pills on the first day of the menstrual cycle
The days of the menstrual cycle: Four phases
(ie the day when the starting monthly). This can be done within 2-5 days of the first cycle, but in this case another 7 days you will need to use a barrier method of protection against pregnancy (eg, condoms).
If you've used other hormonal contraceptives, it is recommended to start taking Jeanine on the next day after taking the last active tablet of your previous contraceptives, but in any case no later than after the usual seven-day break (if the package 21 tablets) or one day after the last inactive tablets (if multiples of 28 tablets).
Those who had previously taken the contraceptive progestin may begin to note Jeanine without interruption or within seven days after the receipt of other contraceptives. The sooner a woman starts receiving new contraceptives, the sooner it will be protected from unwanted pregnancy.
After the abortion done in the first trimester of pregnancy, you can begin to take Janine immediately on the day of the abortion. This will provide instant protection from pregnancy. Since, in practice women resume sexual activity until several weeks or even months after a miscarriage, you may want to start taking Jeanine, when to begin the first normal period after an abortion.
After delivery or abortion in the second trimester of pregnancy is recommended to wait 21-28 days before you start taking Jeanine. Again, in practice, women after the pods or late-term abortions rarely begin having sex too early. As a rule, the minimum recovery, both physical and psychological, must be not less than six weeks. Therefore, it is best to start taking Jeanine after the doctor will tell you that your body is sufficiently recovered and seven days before the actual resumption of sexual activity.
If you forget to take the pill
Protection against pregnancy is not reduced within thirty six hours after ingestion of the tablet. If you forget to take one of the pills and remembered it for twelve hours, take it as soon as possible and take the next, as usual. If it has been more than twelve hours, take the tablet (even if you have to take two tablets at the same time), and continue to take, but for seven days, use additional means of contraception.