What is demodex

Demodex - is subcutaneous mite, which is the skin of most people. Under certain conditions it can cause disease (ie, is opportunistic parasite). More frequently, Demodex does not prove anything. Lives demodex in the hair follicles, sebaceous glands, meibomian glands of the eyelids and is a very small (less than mm in length) of the tick-coated shell protects it. This shell has three layers and is well protected from any danger of demodex. In the shell there are no holes, so demodex can hide for a long time and are not communicated to the outside world. This feature gives the structure of demodex special stability, so the disease that it causes, very difficult to treat.

Under normal conditions on healthy skin demodex is a harmless inhabitant of the skin. But under certain conditions it can contribute to the development of skin disease - demodicosis. A prerequisite for the development of demodicosis is a change of the sebaceous glands and the chemical composition of sebum (usually this is in violation of hormonal), violation of the permeability of capillaries (the smallest blood vessels located in the deeper layers of the skin) and the reduction of protective abilities of the skin. Such changes in the skin contribute to the enhanced reproduction of demodex, while there are conditions to bring out its pathogenicity, ie the conditions for the occurrence of inflammation caused by mites.

Today's environmental conditions reduces the protective properties of the organism (immunity) and the formation of various hormonal disorders, so the incidence of demodex Acne - self-healing is not possible   It is growing, and the disease itself with each passing year it becomes more difficult to treat, as well, even after the treatment is constantly relapse. Not the last role played by chronic diseases and foci of infection that weaken the body of modern man.

How does demodekoz

Acne manifests itself in different kinds of rashes on the skin, mainly in areas where the most sebaceous glands. The skin becomes inflamed, scaly, and shows small inflammatory rash. Often, such a process is attached to a bacterial infection, and then the rash becomes purulent. Inflammation occurs primarily in the roots of the hair (hair follicles).

As demodicosis is prolonged and chronic, it is sometimes confused with skin appearances systemic connective tissue diseases - lupus erythematosus. Exacerbations demodectic mange most often occur in spring and summer. Prolonged skin inflammation in places of permanent rash begins to thicken. Often, it is covered with purulent scales.

Since demodicosis causes low immunity Immunity - types and characteristics in children in adults Often joined by other skin diseases, both bacterial and viral.

As confirmed diagnosis of demodectic mange

The diagnosis can be confirmed demodicosis saw under the microscope a large number of pathogens in the scrapings from skin changes, crusts or secretions of sebaceous hair follicles. Before taking the material for laboratory study of patients are advised not to wash during the day and do not use any drugs for ten days.

In some cases, examined the tissue of the lesion - this allows you to see how much change skin: dilated capillaries, their walls are thickened, enlarged sebaceous glands, and hair roots are destroyed.

How to treat a disease caused by demodex

First of all, it is required to put in normal skin. To that end, appoint a diet (anything spicy, fatty, sweet, sweet), patients are advised not to drink alcohol or smoke. Protective treatment for the skin - the exception of natural (sun, wind, cold, dust, etc.) and water-thermal effects (but not for baths, saunas Sauna and health: the benefits and harms of bath procedures   and so on). Carry out general treatment, strengthens the body's defenses (immune system).

Current treatment regimens demodekoza Acne - Treatment: how not to hurt even more?   includes coursework assignment such drugs as metranidazol and tiberal (they kill demodex). Appointed sosudoukreplyayuschie drugs, physiotherapy, local preparations for the destruction of demodex and removal of inflammation in the skin. Always disinfection bed clothes.

Prevent the emergence of demodectic mange is only possible by a constant proper skin care.

Galina Romanenko

Immunomodulators for the treatment of psoriasis

Immunomodulators used in psoriasis in recent decades - they suppress the ability of immune cells to reproduce. All immunomodulators can be divided into two groups: the preparations of general action that suppress the immune system as a whole (metatreksat, cyclosporine) and new drugs for psoriasis selective (selective) actions that inhibit only certain parts of immunity (efalizumab, thymodepressin, alefacept, and basiliximab (Simulect) infliximab, adalimumab, ustekinumab).

Methotrexate for psoriasis has long been used, but now it is administered less frequently due to the large number of side effects. Methotrexate (tablets for psoriasis) is a folic acid antagonist and inhibits the division of cells throughout the body, causing side effects such as nausea, vomiting, canker oral mucosa, thrombocytopenia, toxic hepatitis Toxic hepatitis - the impact of harmful substances on the liver , Kidney disease, and so on. Today metatreksat for psoriasis are used only when the disease is not treatable by other methods.

Another drug in this series - Cyclosporine also has a general effect on the immune system and, therefore, is applicable only in case of emergency.

New drugs for psoriasis - immunomodulators selective (selective) action or monoclonal antibodies act only on the part of the human immune system that causes psoriasis and its subsequent manifestations. Prior to their use in the treatment process should be carried immunoassay to avoid missing negative changes in the immune system. In general, these drugs do not have adverse effects on vital organs. It is an effective treatment for psoriasis, which is now almost replaced the first-generation immunomodulators.

Antibiotics for psoriasis - are they necessary?

Antibiotics are used in psoriasis if the body of the patient revealed some inflammatory foci supporting exacerbation of psoriasis - adenoid Chronic tonsillitis - inflammation of the tonsils , Sinusitis Sinusitis - when a puncture is required , Medicine and so on.

Useful antibiotics and weeping forms of psoriasis, when there is a threat of secondary bacterial infection. The risk of infection increases significantly when used glucocorticoid hormones. The choice of antibiotic depends on where both developing infectious-inflammatory process.

New cure for psoriasis based on vitamin A

In severe forms of psoriasis today successfully applied new tools for psoriasis - drugs from the group of retinoids used in niperkeratozah. These drugs include neotigazon sold in capsules. Neotigazon - a synthetic aromatic analogue of retinoic acid, which has no direct toxic effect on the liver, as well as mutagenic and carcinogenic action. But it is teratogenic (negative impact on the fetus) and therefore can not be used for treatment of pregnant women.

Neotigazon Assign inside of individualized dosage, because of individual differences in the absorption and rate of metabolism of the active active ingredient dose should be adjusted individually. The capsules are best taken once during a meal or milk. The course of treatment - up to several weeks. After the extinction of psoriatic plaques of patients with psoriasis treatment can be stopped.

Side effects of this drug known dry mucous membranes, inflammation of the lips, hair loss, petechial hemorrhages in the skin, vomiting, hepatitis Hepatitis - the scourge of our time . All these side effects are reversible and quickly disappear after drug withdrawal.