With thyroid hormones in the human body is regulated by the metabolism
Improves metabolism and losing weight without dieting
Growth and development of all organs and tissues, maturation of bone and brain tissue, as well as the growth of the organism as a whole. In connection with this violation of the structure or function of the thyroid gland is required to cause a variety of disturbances in the whole organism.
As there is hypoplasia of the thyroid gland
Hypoplasia of the thyroid gland - a congenital hypoplasia of its tissue, which manifests itself in the form of cretinism. Full congenital absence of the thyroid gland is rare and is called aplasia. If such changes in the thyroid gland are acquired (secondary) character, hypoplasia
Hypoplasia - a congenital malformation of the fetus
They can not be called: in accordance with the existing installations reducing the volume of all secondary thyroid gland called atrophy.
Hypoplasia of the thyroid gland may occur with insufficient iodine in food and water in areas, where a pregnant woman (epidemic cretinism) or hereditary defects of enzyme systems involved in the synthesis of thyroid hormones
Thyroid hormones: mechanism of action and physiological effects
(sporadic cretinism).
Changes in humans with hypoplastic thyroid
When cretinism is detected as a decrease in the amount of thyroid and diffuse or nodular goiter. In the region of goiter found single cells of the thyroid gland in the background proliferation of connective tissue (sclerosis), cysts and calcification (deposition of calcium salts). Increases in size and anterior pituitary that produces thyroid stimulating hormone (TSH) to stimulate the secretion of thyroid hormones (thyroid hormone).
Almost all organs are reduced in size and underdeveloped, especially the genitals. Characterized as bone changes: the skull bones are deformed, its base is underdeveloped compared to the vault, frontal and parietal bones, thickened. If childhood not timely treatment was conducted, further changes in the organism would not succumb correction.
Symptoms of thyroid hypoplasia
The main symptoms of cretinism is a dramatic delay in physical and psychological development, as well as neurological disorders. Cretinism is divided into two types - nerve (dominated by disorders of the central and peripheral nervous systems with reduced intelligence and movement disorders, disorders of hearing and speech) and myxedema (with a predominance of symptoms of hypothyroidism - thyroid function decline).
Outwardly, patients are characterized by very small stature, short legs and arms, a round face with a broad nose, short neck and an enlarged abdomen. Roth they often slightly opened due to increased language.
Skeletal muscle have poorly developed, resulting in gait disturbance, and slow motion. And genitals are underdeveloped, and therefore, even in adulthood, they look like children.
The bones of the skeleton ripen slowly and incompletely, ossification of time does not occur often, even in adults remains open areas of growth in the long bones. Long bones (humerus, femur, etc.) are shortened and thickened, lumen inside them, where the bone marrow is narrowed.
Always there are neuro-psychiatric disorders, expressed in varying degrees, from mild impairment to full disorder of intelligence and inability to self-service. In some cases, patients suffering from cretinism, still manages to absorb some knowledge about the world, but to carry out a permanent job, they can not, because it is very slow and constantly interrupt their activities.
The emotional life of these patients also depleted they are closed, sluggish, indifferent, drowsiness, constantly seeking privacy and sleep in the warmth. By friendships (including a close relationship with members of the family), they are usually not arranged. Some are prone to depression, outbursts of ill will and even aggression, but quickly calm down, if they are well treated.
What is revealed by examination of the thyroid gland
The blood of these patients revealed a decrease thyroid hormone levels and increase the level of thyroid stimulating hormone of the pituitary gland. Diagnosis is based on the major symptoms of the disease, laboratory data and radiographic bone.
Hypoplasia of the thyroid gland in adults today is very rare, because of the prenatal development of the child
Prenatal development of the child: Week by Week
constantly observed in the women's consultations, including with the help of ultrasound and after childbirth immediately carried out substitution therapy with thyroid hormones.
Galina Romanenko
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- hypoplasia of the thyroid gland