The complexity and the large number of causative factors, which are involved in the development of pathological changes in the thyroid gland, leads to a variety of clinical manifestations. Symptoms depend on the thyroid blood levels of thyroid hormones and their effect on the function of the major organ systems. Impact of cancer on the human body is a versatile, so in the pathological process may involve various agencies.
Symptoms of the disease with an excess of hormones
If thyroid hormones are secreted in excess, it will lead to the development of the clinical picture of Graves' disease or diffuse goiter. All the symptoms can be divided into fundamental (or basic) and other symptoms associated with the pathological influence of hormones on other organs. By radically symptoms include the following:
- an increase in the size of the gland, or goiter
- exophthalmia or exophthalmos
- tremor
- changes in heart rate (tachycardia)
These symptoms are present in all patients with a diagnosis of diffuse goiter. Characterized by the presence of a number of eye symptoms, ie, pathological changes in the eye. Changes in the eye can be seen not only in patients with diffuse goiter
Diffuse goiter - pay attention to the eyes
And hypothyroidism, thyroiditis with, in some cases it may precede the appearance of other pathological symptoms. Exophthalmos occurs with other symptoms, such as a wide-open eye slits, high luster eyes. Changes in the eyes of patients form a kind of expression, which can be called an expression of fear. It appears glare at fixation. Character changes the eye does not affect the degree of visual acuity only in severe disease severity acuity decreases. Also, there are complaints of mood changes (appearance of patients reported increased nervous irritability, tearfulness, nervousness, restlessness). It is the cause of conflict in the family and at work, as these people become overly activities hypochondriac and quarrelsome. Disturbed sleep up to insomnia.
Noteworthy is progressive weight loss during preservation, in some cases even increased appetite. Since thyroid hormones are secreted in large amounts, it is enhanced consumption of energy resources in the body. This is the immediate cause of weight reduction. This picture is not in all cases, there are patients with goiter, whose body weight is excessive. It was called "fat Grave." Have changes in body weight requires individual selection of medical therapy. Particularly noteworthy are the clinical symptoms that arise from the heart and blood vessels. Excess levels of hormones has a toxic effect on the myocardium, which is the cause of severe metabolic and degenerative lesions. The most constant symptom is increased heart rate (or tachycardia). Characteristically, rapid pulse passes during sleep
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, No changes with a change in body position, and the response to the reception of cardiac glycosides is weak. The pulse rate in some cases, can reach up to 160 beats per minute. Patients feel the heartbeat of the rapid pulse in the abdomen, head and neck. According to researchers leading cause of death in diffuse goiter is associated with the problem of cardiovascular complications. Those processes that underlie the development of heart failure in the crop, are reversible, so it is important to set the correct time diagnosis and appropriate therapy.
Interconnection of viral infections and thyroid pathology
During the autumn-winter period of time has been an increase in the incidence of inflammatory changes in the thyroid after undergoing a viral infection (after adenoviral infection, measles
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or mumps). A few months after infection the patient has typical complaints related to inflammatory changes in the thyroid gland (thyroiditis development). The disease develops acutely, there is pronounced weakness, malaise, neck pain radiating to the ear. The pain will intensify when swallowing and movement. Objectively during the inspection revealed an increase of iron, often diffuse goiter. Attaches common symptoms associated with an inflammatory process:
- marked weakness and malaise
- increased sweating
- changes in clinical analyzes of blood (increase above normal ESR parameter, in some cases up to 100 mm in h., the content of leukocytes unchanged). Characteristically rapid development of these changes
It is important to make a differential diagnosis with various forms of thyroiditis. If the process involves only a single share body (focal or focal thyroiditis), it is necessary to exclude malignancy or carcinoma. The main clinical symptoms are the same as in these diseases (complaints of pain, changes in body size and density), so in the process of diagnosis must rely on the results of additional instrumental methods.
If inflammation of the thyroid gland occurs in the form erased without an acute disease, the symptoms will be quite meager. The patient to see a specialist endocrinologist only at the stage of development of complications, such as symptoms of hyperthyroidism
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. This can lead to delayed diagnosis installation. An important diagnostic criterion in this situation would be the level of thyroid hormone, pituitary hormones central. Diagnostic value of clinical manifestations will have no material value individually without considering the hormonal profile of the patient.
Marina Solovyov