The active ingredient is Bonviva ibandronic acid, which belongs to a group of medicines called bisphosphonates. Bisphosphonates are used to prevent the destruction of the bone tissue. Bonviva is indicated for the treatment of osteoporosis Osteoporosis - he threatens you?   postmenopausal women. Ibandronic acid binds to bone cells, preventing them from osteoclasts lead calcium.

The studies found that Bonviva significantly reduces the risk of vertebral fracture Fracture of the spine - how to get out with minimal losses?   in postmenopausal women, but it is unknown how this preparation is effective for preventing hip fracture.

Bonviva is available as tablets and injectable solutions. In tablets it is taken once a month, preferably - in one and the same day each month. For some patients the doctor injects Bonviva once every three months.

How to take the drug

It is important to take Bonviva tablets in strict accordance with the instructions, as it can cause irritation and even ulceration of the esophagus.

Taking Bonviva should be in the morning, before you eat or drink, no matter what it was. Thus at night, at least six hours before ingestion, it is necessary to avoid taking any food in any quantity.

Swallow the tablet whole and drink down her glass of simple clean water (180-240 ml, without mineral and carbonated water).

Do not lie down for at least an hour after taking the pill. Also within an hour should not eat or drink anything other than plain water. This is due to the fact that certain foods and beverages can disrupt the absorption of the drug and reduce its effectiveness.

Within six hours before receiving Bonviva within one hour after ingestion can not be taking other oral medications.

Caution

Any sign of irritation of the esophagus while receiving Bonviva should stop taking the drug and seek medical advice.

Admission bisfosonatov been associated with a rare disease - osteonecrosis of the jaw. The risk of developing the disease increases with poor oral hygiene Oral hygiene - not only in the dentist's chair   and various problems with teeth and gums. For this reason, during the course of treatment should undergo regular dental checkup.

Contraindications

Contraindications to receiving Bonviva are:

• Abnormalities of the esophagus, which may lead to difficulty in swallowing;
• Allergies to the ingredients medications (including non-active substances);
• Any condition in which the patient is unable to sit or stand upright for at least 60 minutes after taking the drug;
• Such rare genetic disorders, like galactose intolerance, lactase deficiency or glucose malabsorption Glucose: The energy source galactose.

Information on the effects of the drug on children, pregnant and lactating women is missing - studies have been conducted since the drug is not commonly prescribed to patients belonging to these groups.

Bonviva should be taken with caution at reduced renal function, disorders of the parathyroid gland, deficiency of vitamin D, the active upper part of the digestive disorders system such as gastroesophageal reflux disease, ulcer, gastritis, inflammation of the duodenum.

Complications

Bonviva can cause the following complications:

• The low levels of calcium in the blood (hypocalcemia);
• Flu-like symptoms;
• Stomach upset;
• Nausea and vomiting;
• Abdominal pain;
• Diarrhea;
• Pain in the bones;
• Pain in joints or muscles;
• Weakness;
• Headache;
• Dizziness;
• Inflammation of the esophagus (esophagitis - only when receiving Bonviva as tablets);
• Difficulty swallowing (only when taken in pill form);
• Gastritis;
• Skin rash;
• Inflammation of the eye;
• Osteonecrosis of the jaw.

Drug Interactions

The risk of irritation of the esophagus when receiving Bonviva may increase, if the patient is also taking NSAIDs, such as ibuprofen, diclofenac or indomethacin, and aspirin. People taking Bonviva is better to avoid these painkillers.

The risk of excessive loss of blood calcium level is increased if the patient along with Bonviva receives aminoglycoside antibiotics such as gentamicin.

The basic metabolic rate changes during the life - in different periods of his are ups and downs. How to maintain a healthy weight at any time, despite the age-related changes of metabolism?

Transitional age

The metabolism is accelerated due to the general changes occurring in the body. Normal levels of physical activity (it may be just walking or cycling) and proper nutrition Proper nutrition - the basic precepts of healthy food   - All you need Adolescent Health to maintain an optimal weight.

20+

After twenty years of metabolism Improves metabolism and losing weight without dieting   It begins to slow down. The average baseline metabolism of this time will be reduced by 1-2% in a decade. This is a normal process associated with a gradual decrease in muscle mass. If you exercise regularly (be sure to perform strength exercises), slowing metabolism Metabolism: The basis of life of all living things   It will not affect the weight.

Gestation

During pregnancy, metabolic processes are accelerated. For a child to develop normally from the moment of conception Conception, ovarian cycle, fertilization and genetics of a child   before birth, it takes about 80,000 calories, that is, the expectant mother should be getting about 300 calories a day more than its usual standards. Eating for two, as discussed earlier, it is not necessary - if, of course, you do not want to just after the start of pregnancy to fight obesity.

After pregnancy

Metabolism even more accelerated. If you are breastfeeding, your body spends about 500 kcal per day in the production of milk. Shortly after you stop breastfeeding, the metabolism will drop to the level that was before pregnancy, and you need to reduce your calorie intake accordingly.

From 40 to 50 years

The body's cells are not updated as quickly muscle mass has decreased significantly, and at the same time reducing the need for calories. If 25 years to maintain optimal weight without dieting, you need howled run five times a week for five kilometers, but now it needs to run seven kilometers.

Menopause

Metabolic processes continue to slow down and this, combined with the fact that many women after menopause become less active, is the main reason that obesity is a common problem in this age group. You must reduce your calorie intake, and to continue to engage in activities to maintain a healthy weight in adulthood.