Smecta is the drug of natural origin, cleanses the body from various substances and has little contraindications. However, do not abuse this drug: with harmful substances to the body, he can bring some useful.

Features action smekty

Smecta refers to a group of absorbent and antidiarrheal (against diarrhea) drugs. It perfectly cleanses the intestines, moving it slowly and adsorbed on the surface everything superfluous. Interestingly, due to its structure smectite Smecta - necessary in any medicine cabinet   does not take mineral salts, it is very important for diarrhea of ​​various origins, which are the main risk is that, along with salts derived fluids and dehydration occurs.

Smectic A very important property is the fact that it clears the mucosa of the gastrointestinal tract and also strengthens its protective properties. This is especially important in intestinal dysbacteriosis Intestinal dysbiosis - how dangerous it is? Who can always go in chronic colitis.

Smectite take for diarrhea of ​​any origin, for poisoning, chronic diseases of the gastrointestinal tract, as well as heartburn, flatulence, intestinal colic.

Why smectite is contraindicated in intestinal obstruction

Ileus - a condition in which the passage is broken stool through the intestines due to its obstruction (blockage), squeezing or simply malfunction. Such disorders may be due to the fact that the path of the stool there is some obstacle (mechanical obstruction) due to temporary disturbances of motor activity of the intestine (dynamic obstruction) and circulatory disorders in the bowel (obstruction of vascular origin).

If a patient with intestinal obstruction in time will not be given the necessary assistance, it will develop severe complication of necrosis (tissue death) and perforation of the intestinal wall, causing inflammation in the transition to the abdominal cavity - peritonitis.

Smecta contributes to the slow progress of stool through the intestines, and hence constipation. Constipation also further increase the degree of intestinal obstruction. Therefore, even in cases of suspected intestinal obstruction smektu take in any case impossible.

Why smectite is contraindicated in case of intolerance and fructose malabsorption syndrome glucose and galactose

Fructose intolerance - an inherited disease in which the body can not use fructose food, because it does not produce enzymes, it transforms (fosfofruktaldolaza). This substance accumulates in the body resulting from the exchange of fructose (fructose-1-phosphate), which blocks the formation of glycogen and conversion into glucose - the energy material necessary for the functioning of the body.

Therefore, entering the food even a minor amount of fructose or sucrose (i.e. sugar, which is converted in the body into fructose) causes a decrease in glucose Glucose: The energy source   in the blood (hypoglycemia). Hypoglycemia manifests weakness, sweating, tremor of the whole body, nausea, vomiting, and sometimes convulsions, followed by loss of consciousness and coma. With long-term eating fructose developing renal dysfunction, liver and brain, which manifests itself in the reduction of intellectual abilities.

Treatment of this disease is the removal of the fructose diet (including sweet fruit) and sucrose.

Another enzymatic disease - lack of sucrase - isomaltase - an enzyme that breaks down sugar. Such patients also can not eat sugar.

Powder smekty consists of active principle (dioctahedral smectite) and excipients, which include and simple sugars, which are contraindicated in patients suffering from enzyme deficiency.

Another Contraindications - hypersensitivity to the drug

Increased sensitivity can be the patient to any drug or food substances. Increased sensitivity to a particular drug may be allergic (immunologic) and non-allergic in nature. In allergy develop typical allergic reactions such as urticaria, edema Prevention and treatment of edema - it is important to understand the root cause   Angioedema, anaphylactic shock, and so on. Hypersensitivity nonallergic nature has similar manifestations, but substances that contribute to the manifestation of a hypersensitivity reaction, are allocated through other mechanisms.

In any case there is a threat of severe reactions, so these people do not take smektu better.

Galina Romanenko

Pariet - a drug with anti-ulcer effect. Assign Pariet for the treatment of gastric ulcer and duodenal ulcer (including an infection caused by the bacterial pathogen Helicobacter pylori), ulcerative lesions of the esophagus and other diseases.

How does pariet

Active ingredient is rabeprazole sodium Pariet - a substance with antisecretory action. It produces pariet international pharmaceutical company Janssen tablets, enteric-coated. Each tablet contains 10 or 20 mg of rabeprazole. Excipients are mannitol, magnesium oxide, magnesium stearate, low substituted hydroxypropylcellulose, ethylcellulose, hypromellose phthalate, monoglyceride diacetylated, talc, titanium dioxide, red iron oxide, ethanol (evaporates during production), Purified Water (evaporates during production), carnauba wax gray edible food gray ink, 1-butanol (evaporates during manufacture).

Pariet is a proton pump inhibitor, ie it inhibits the action of the enzyme hydrogen-potassium ATPase (H + / K + -ATPase). The action of this enzyme is associated with violent release (this action uses the energy that is produced by the decay of ATP) from the cells of the gastric mucosa in the gastric lumen of hydrogen ions (H +) in exchange for potassium ions (K +). Potassium first enters into the cell, and then picks up from the cell chlorine (Cl) and, with it again passes into the gastric lumen. Because hydrogen and chlorine forms hydrochloric acid (HCl). Pariet blocks the action of the enzyme H + / K + -ATPase and thereby inhibits the formation of hydrochloric acid. And since increased acidity contributes to the development of ulcerative process, the drug has anti-ulcer effect.

The therapeutic effect of Pariet is dose-dependent and results in a gradual release of hydrochloric acid suppression of gastric glands. As slightly alkaline substance rabeprazole in any dose is rapidly absorbed and concentrated in the acidic environment of the stomach mucosa cells.

Ingestion tablets of rabeprazole 20 mg in an hour causes a decrease in gastric acid secretion. The maximum effect is achieved in two to four hours, and lasts for two days. The therapeutic effect of the drug increases when it is taken daily and reaches its maximum three days. After treatment the secretion recovered in three days.

Pariet distinctive feature is its ability to suppress the vital activity of bacterial pathogen Helicobacter pylori - the main "culprit" of gastric ulcer and duodenal ulcer.

Which diseases appoint pariet

Pariet is prescribed for diseases of the gastrointestinal tract that are accompanied by high acidity of gastric juice:

• gastric ulcer and duodenal ulcer, including for the treatment of these diseases, if the main reason for their development is Helicobacter pylori;
• gastroesophageal reflux disease (GERD) - a disease of the stomach and esophagus are associated with increased acidity of gastric juice; when reflux esophagitis acidic gastric juice is constantly thrown into the esophagus, causing canker its walls;
• Zollinger-Ellison syndrome - a benign tumor of the pancreas Diabetes and pancreas - the things you need to know Which produces gastrin stimulates gastric acid secretion; the disease can be severe, while pariet appointed Adjusted dosages, duration of therapy and individual;
• if the target application is the suppression of vital Pariet Helicobacter pylori, then it is administered together with an antibiotic.

Contraindications for use Pariet

Application of Pariet is contraindicated in pregnancy (crosses the placental barrier), feeding baby Breastfeeding - a personal choice   breasts (not known whether pariet breast milk), children (clinical trials on children were not carried out), as well as hypersensitive to the components of the drug to other drugs in this group.

Side effects

Pariet is generally well tolerated, but sometimes may develop side effects:

• the part of the digestive system - nausea, vomiting, constipation or diarrhea, abdominal pain Abdominal pain: Types and Symptoms , Bloating, dry mouth, loss of appetite, transient liver dysfunction, manifested in the form of changes in laboratory parameters;
• the central nervous system - general weakness, decreased performance, headaches, dizziness, insomnia or drowsiness;
• from the blood - decrease of blood cells and platelets that prolonged use may lead to reduced immunity and increased bleeding;
• may also occur - the allergic reaction, stomatitis Stomatitis - to breath fresh , Back pain, joint and muscle pain, flu-like symptoms, weight gain, depressed mood, impaired vision or taste.

Galina Romanenko