Dekaris was synthesized in the middle of the last century. Initially, it was used as a worming medication, and then were found and immunostimulatory properties decaris. As immunostimulant dekaris actively used for several decades. Today, as an immunostimulant dekaris is rarely used because of the low efficiency and the presence of side effects.
How does dekaris
Active ingredient is decaris levamisole - a synthetic substance with anthelminthic properties. Levamisole suppresses the action of certain enzymes involved in the implementation of neuromuscular function helminths. This leads to the complete immobilization of helminths and their excretion with feces from the normal intestinal peristalsis during the day. Levamisole is active only in relation to helminth infections caused by round worms - nematodes. It is especially effective in the treatment of ascariasis.
Furthermore, dekaris provides easy and immunomodulating action, selectively stimulating regulatory function of T-lymphocytes. It can stimulate cell-mediated immunity is weak, weaken the strong and did not affect the normal. However, as an immunomodulator dekaris used today is limited because of the low efficiency in combination with the presence of fairly significant side effects.
It produces dekaris pharmaceutical company Gedeon Richter (Hungary) in tablets of 50 and 150 mg. When receiving the pills inside it quickly absorbed in the gastrointestinal tract into the bloodstream and reaches high concentrations within two hours. In the liver, levamisole is decomposed into inactive metabolites and then excreted primarily in the urine.
Which diseases appoint dekaris
The main indication for decaris are helminth infections caused by roundworms - ascariasis, necatoriasis, strongyloidiasis, trihostrongiloidoz, hookworm, toxocariasis.
In addition, in some cases dekaris appoint and as an immunomodulator. Indications in such cases are primary and secondary immunodeficiency states, often chronic recurrent infections, rheumatoid arthritis
Arthritis - a variety of forms and complications
, Lupus erythematosus, tumor. Dekaris sometimes prescribed to children, often ill colds.
Apply dekaris strictly on prescription, and released at the pharmacy on prescription. It is better to take in the evening, after a meal with a small amount of water. Laxatives or any special diet is not required. On prescription reception decaris can be repeated after one or two weeks.
Are there any contraindications for use decaris?
Dekaris can not be used while feeding the baby
Breastfeeding - a personal choice
breast - in this case, or temporarily stop breastfeeding, or decide on the appointment of another drug. Do not take dekaris children up to three years if the patient previously developed agranulocytosis (lack of white blood cells responsible for cell-mediated immunity) while taking some medications and hypersensitive to the components of this drug.
Precautions dekaris used during pregnancy (only emergencies), with severe liver and kidney diseases with dysfunction of these organs, as well as violations of hematopoiesis.
Admission decaris can not be combined with reception of alcoholic beverages, as dekaris suppresses the decomposition and excretion of alcohol, and this in turn can cause a severe reaction to a sharp decline in blood pressure, facial flushing, dizziness
Dizziness - if the ground is slipping from under his feet
, Headache, nausea, vomiting and so on.
Nor should combine reception decaris with taking medications that suppress the process of hematopoiesis, kumarinopodobnyh anticoagulants (drugs that reduce blood clotting) and lipophilic (ability to accumulate in fatty tissue) products (carbon tetrachloride, tetrachlorethylene, oil henopodiya, chloroform, ether), as its Toxicity may increase.
Side effects and overdose decaris
Side effects decaris usually appears with increasing dose over the recommended or for prolonged use. In this case, the patient may appear headache, dizziness, nausea, vomiting, diarrhea, abdominal pain
Abdominal pain: Types and Symptoms
Insomnia. Sometimes seizures may occur. It is also possible development of allergic reactions and adverse impact on the hematopoietic system.
Side effects can be remote - a month after taking the drug in the form of encephalopathy.
An overdose of the drug is in the form of increased side effects and requires gastric lavage and call an ambulance.
Dekaris - it anthelmintic drug with some immunomodulatory properties, which today is used for the treatment of helminthiasis.