Geptral - is a drug, the main effect of which is related to the protection of the liver from the harmful effects and restore its function. In addition, it has positive effects on the central nervous system, as has antidepressinymi properties, i.e. improves mood in patients suffering from depression.

How does Heptral

Active ingredient is geptrala ademetionine - a substance that is present in the body of all people. Ademethionine acts at a cellular level, it restores the ability of liver cells (hepatocytes) resulting in a display in which bile bile ducts, removing thus intrahepatic bile stasis, which destroys the hepatocytes.

At the same time contributes to Heptral production of biologically active substances, protects liver cells from any toxic effects (free radicals, toxins formed during metabolism Metabolism: The basis of life of all living things   or entered from the outside), and prevents the destruction of hepatocytes, followed by the growth instead of connective tissue cells - inhibits the formation of cirrhosis.

Geptral issued international (in general, the US) pharmaceutical company Abbott in the form of tablets, enteric-coated and lyophilized powder for solution for injection in vials. Both formulations contain 400 mg of active principle per tablet or vial.

As an antidepressant Heptral improves metabolic processes in the brain cells (neurons), which helps to relieve the symptoms of depression Depression - a little more than a bad mood .

Assign this drug long course of treatment. It has been established that he is able to significantly restore liver function and stop the destruction of hepatocytes and the subsequent development of cirrhosis (growth of connective tissue with a loss of liver function) of any origin.

Which diseases apply

Geptral can be applied at any diseases of the liver and biliary tract. The only exception is gallstone disease: increased amount of bile can cause attacks of biliary colic due to the blockage of hepatic duct stones.

It is especially effective when Heptral cirrhosis of the liver developing on the background of various intoxicants - alcohol, drugs, and other drugs. In this case, on the one hand it protects the liver cells from destruction by toxins and other suppresses growth of connective tissue. This brings to a halt the progression of the pathological process and prolongs the life of patients. Apply Heptral for removing the state of abstinence, which develops in isolation from alcohol or drugs the patient, who has formed a physical dependence to these substances.

Geptral beneficial effect on the liver and viral hepatitis including chronic - in this case also slows down the destruction of liver cells and loss of function of that organ.

In diseases of the biliary tract Heptral helps to maximize the removal of bile and removal of stagnation in the liver cells (choleretic action) and in the bile ducts (holekineticheskoe action).

When depression Heptral actively influences the metabolic processes in the brain cells (neurons), which helps to improve their functions and the removal of the patient out of the doldrums.

Who should not take Heptral

Geptral well tolerated and almost no side effects, except for rare cases of allergic reactions Allergic reactions: how to understand why you tickle in the throat . Sometimes also possible discomfort and pain in the stomach and heartburn that usually do not require discontinuation.

Do not take Heptral case of hypersensitivity to the drug component of the patient, the presence of stones in the biliary tract (cholelithiasis), as well as the first and second trimesters of pregnancy, while feeding the baby Breastfeeding - a personal choice   chest and under the age of 18 years.

With caution and only under laboratory control Heptral prescribed for severe kidney disease in violation of their functions.

Not recommended Heptral afternoon, as it has a stimulating effect on the central nervous system.

Manufacturers also recommend not to use a pill or powder geptrala if he changed the characteristic white color.

Geptral - it is a safe drug, which usually does not cause overdoses and perfectly combined with taking other drugs. However, in drugstores it can only be bought on prescription, since its effectiveness depends on the correct destination.

Galina Romanenko

Vermoxum - anthelmintic drug is a broad-spectrum. Most often it is used to treat round and tape worms - pinworms, ascarids, whipworm, pork tapeworm. It is highly effective drug that take no more than three consecutive days, and most of all - a one-off.

The mechanism of action Vermoxum

Vermoxum (INN - worming remedy mebendazole _- wide spectrum of action, which produces the Hungarian pharmaceutical company Gedeon Richter in the form of tablets of 100 mg and 2% of the suspension. In other pharmaceutical companies produced analogues Vermoxum under the names - vermakar, Vero mebendazole, vormin, mebeks, mebendazole, telmoks.

By Vermoxum sensitive all round and tape worms Worms - how dangerous they are? But it is most effective against pinworms and whipworms. Once in the gastro-intestinal tract into the body Vermoxum wilts and helminths cause metabolic disorder, in particular gives the assimilation of glucose and the formation of its energy in the form of ATP. In the absence of the energy are stopped and all other exchange types, whereby helminths die and out from the intestine.

The main part of Vermoxum remains unchanged in the intestine and comes out with the faeces. However, about 5 - 10% absorbed into the bloodstream. Thus Vermoxum better absorbed when it is taken with food, especially fat, which reduces its effectiveness against helminth located in the intestines. After absorption into the blood Vermoxum binds to blood proteins and accumulates in the liver, adipose tissue and larval cysts. It can penetrate the placenta to the fetus and have an adverse effect on him. It sucks the blood Vermoxum destroyed in the liver (in part) and excreted by the kidneys.

In applying Vermoxum no need to do an enema - dead worms themselves out of the intestine with the feces.

Indications and contraindications for use

Most often used to treat Vermoxum enterobiasis (called pinworms) and trichuriasis (called whipworm). In addition, Vermoxum prescribed for infection of other roundworms (ascariasis, hookworm - caused by hookworm, strongyloidiasis - called ugritsey intestinal, trichinosis - called Trichinella), tapeworm (taeniasis - caused by pork tapeworm, echinococcosis - called echinococcus and some other helminth caused by trematodes ), as well as mixed helminthiasis.

In the period of treatment is necessary to observe personal hygiene (washing hands frequently, daily linen change), since it is possible re-infection with worms and their eggs. Treatment should be initiated sure all family members.

A week after the treatment is carried out laboratory control of cure.

Contraindicated appointment Vermoxum are hypersensitive to the drug, chronic inflammatory bowel disease Inflammatory Bowel Disease: Symptoms and Treatment , Particularly if they are accompanied by the formation of ulcers in the gut wall or erosions - ulcerative colitis, Crohn's disease. In addition, Vermoxum not appointed under the age of two years, as well as during pregnancy and nursing Breastfeeding - a personal choice   breast - it is partially absorbed into the blood passes through the placenta to the fetus and gets into breast milk.

Not applicable Vermoxum the human liver - it is decomposed in the liver and its function if broken, can accumulate in the body. Data on the use of this drug in patients with impaired renal function is not provided by the manufacturer, but it can be assumed that the significant renal dysfunction Vermoxum will also accumulate in the body. With prolonged use Vermoxum recommended a study of the liver and kidneys.

Admission Vermoxum incompatible with alcohol - they can not eat for a day after ingestion. Admission Vermoxum requires a review of insulin dose in patients with diabetes because it lowers the body's need for insulin The principles of action of insulin - the science of saving lives .

Side effects

Vermoxum - a highly efficient anthelminthic, so it has a number of side effects:

• gastro - intestinal tract and liver - nausea, pain during bowel, when taken in high doses long courses - nausea, vomiting, diarrhea, transient abnormal liver function;
• the central nervous system - dizziness and headache;
• from the blood - when given in high doses long course - reducing the number of leukocytes in peripheral blood (leukopenia - the immune system and reduce the threat of joining various infections), increase in the number of eosinophils (white blood cells, which speaks of an increase in sensitization of the body) and the emergence of anemia;
• by the kidneys and urinary tract when administered at high doses long course - the appearance of blood in the urine (haematuria) and kidney tissue elements (cylindruria);
• allergic reactions (skin rashes, including urticaria), angioedema.
• baldness.

Vermoxum - an effective anthelmintic drug.

Galina Romanenko