A medical examination every five women reveal the so-called bending of the uterus. For some, the diagnosis becomes a sentence, and someone just misses remark doctor as makes no complaints. Bend the uterus is not always, but can affect conception or even cause infertility The causes of infertility - heredity and lifestyle . So what is the particular conception during bending of the uterus, and what it is fraught with danger?

The position of the uterus

In the pelvis the uterus is suspended on cords that extend to the pelvic wall. Normally, the skein is located in a small basin, at an equal distance from both walls of the pelvis. The bottom of the uterus "looks" up and anteriorly, and the vaginal portion of the cervix is ​​facing downwards and backwards (to the back wall of the vagina). In such a position between the body and cervix forms an obtuse angle, which faces anteriorly called anteflexio - antefleksio. This is the normal arrangement of the uterus. Due to certain factors or individual anatomical features, the angle can be turned backwards, as they say retroflexio - retroflection or bending of the uterus. Bending of the uterus may also be in the right or left side or in the form of a torsion uterus.

Causes bending of the uterus

Basically, the bending of the uterus occurs during life and rarely as an individual feature of an organism. The reasons for this are varied arrangement of the uterus:

• inflammatory diseases of the uterus and appendages (adnexitis, endometritis);
• cancer of uterus and ovaries (cysts);
• endometriosis;
• the pelvic adhesions;
• the weakness of the pelvic floor muscles and ligaments weakening tone after childbirth, especially during heavy physical exertion;
• extreme loads associated with concussion of the body (high jump, pole vault, ski jumping);
• sexual infantilism;
• bowel disease and related constipation;
• delayed emptying of the bladder and rectum as a child.

The clinical picture of a bend of the uterus

Symptoms of uterine bend manifest in the case of over-expression of the disease or the symptoms that led to it (inflammation, tumor). Patients complain of painful menstruation (womb "kinked" that prevents normal outflow of blood and pieces of the endometrium), irregular menstrual cycle, pain during intercourse, urinary disorders. Menstruation becomes heavy and prolonged. During the ensuing threat of termination of pregnancy is possible or even miscarriage. When vaginal examination, the doctor identifies the position and mobility of the uterus, it is trying to shift in different directions. If the uterus does not move (fixed), there is a pain as it moves, it points to the adhesive process in the pelvis Adhesions in the pelvis: Symptoms and Treatment Which can not only lead to problems when conception but also to infertility. Since the adhesive process involved not only the queen, but the pipe, it is likely that they may be impassable.

Features of conception at the bend of the uterus

If the bend is not so strongly expressed, and is individual anatomical features of the body, then there is no problem conceiving. When excessively pronounced bending of the uterus creates a mechanical barrier penetration of sperm into the uterus due to its inflection. After intercourse, the ejaculate is collected in the posterior vaginal fornix, which aims to position the uterus antefleksio. When you bend the cervix of the uterus it rests on the front wall of the vagina and has no direct contact with the sperm, which can prevent penetration of sperm into the uterus. In addition, with the expressed adhesive process that led to the bend of the uterus, as already noted, possible obstruction or narrowing of the pipe, which also prevents the egg and sperm meeting.

Features that contribute to successful conception at the bend of the uterus

First of all, you must remove the cause that led to the location of the uterus. To treat inflammation of the pelvic organs, and prevention of relapse in the future. Coping with difficult and complex spikes. Appointed physiotherapy, mud and fermentoterapii Mud - a pleasant and useful procedure   resorption of adhesions. Has proven pelvic massage Gynecologic massage physical therapy in a female . Shown physiotherapy exercises to strengthen abdominal muscles and pelvic floor. At home, it is recommended after intercourse to take a pose "Birch", or 5-10 minutes to lie down on his stomach. Posture during intercourse is also important. Desirably Bozeman position, in which case the cervix moves to the center and contact with sperm.

Anna Sozinova

In the struggle with the disease, as we know, all methods are good. Endometriosis refers to one of the most severe gynecological diseases and its treatment is not only long, but also presents certain difficulties. Treatment of endometriosis include both conservative and surgical methods. In the appointment of conservative methods of treatment preference hormonal preparations Hormonal treatments - not only contraceptives . But we should remember that even the use of hormonal methods does not help to achieve one hundred percent success, and completely overcome the disease. In recent years, it has become widely used Zoladex for endometriosis Endometriosis - a serious problem with serious consequences .

Zoladex compared with Danazalom, progestin or estrogen Estrogen - the key to bone health -gestagensoderzhaschimi drugs has a higher efficiency. For example, a recurrence of the disease after a course of therapy is Danazalom 14-32% following treatment with progestins - 12-34%, and after applying Zoladex only 6-12%.

The mechanism of action of Zoladex

The active ingredient of the drug is goserelin acetate (Zoladex contains 3, 6 mg goserelin). The drug is available in a set with an applicator syringe for subcutaneous administration.

Zoladex (Goserelin or) is a synthetic analogue of the natural LHRH (gonadotropin-releasing hormone). With the constant use of the drug suppresses the release of anterior pituitary luteinizing hormone by blocking the receptors in it. As a result, dramatically reduces the formation of ovarian hormones, particularly oestradiol level (it is known that one cause of endometriosis is the high content of estrogen in the blood). The level of female sex hormones in the blood falls to postmenopausal, that is to create an artificial menopause. The concentration of estrogen continues to be reduced under continuous treatment. Consequently, the patients developed a positive response endometriosis.

Zoladex is synthesized as a depot releasing hormones agonists, so its introduction is carried out once every four weeks. The drug causes thinning of the endometrium, which leads to the development of amenorrhea The absence of menstruation (amenorrhea) - ambiguous symptom   and suppresses the growth of endometrioid heterotopias. As a rule, Zoladex administered in combination with iron supplementation, which causes improvement in hemoglobin and red blood cell count (endometriosis is often accompanied by the development of chronic post-hemorrhagic anemia). In rare cases, treatment WG analogues of LH (particularly Zoladex) give rise to menopause, which does not disappear (menstrual cycle is not restored) after the end of therapy.

The drug has an almost complete bioavailability, and its use is in compliance with the recommendations on dosing provides pronounced effect goserelin no clinically significant accumulation in the body. Zoladex practically does not bind to plasma proteins, and its half-life period of two to four hours. An increase in half-life of the active substance in patients with renal and / or hepatic insufficiency, but the duration of treatment Zoladex it does not require changes in the dosage of the drug.

Dosage regimen Zoladex for endometriosis

Zoladex used in medicine, not only for the treatment of endometriosis. The drug is widely used in the treatment of uterine fibroids, hormonal-dependent cancers of the breast, and in the treatment of prostate cancer in men.

In endometriosis Zoladex injected subcutaneously in the anterior abdominal wall at 3, 6 mg once per 28 days. The drug is administered as a capsule that creates a depot in the body and out over four weeks released active ingredient - goserelin. The duration of treatment is six months Zoladex. A longer course of treatment is not appropriate (risk of persistent menopause). Before the appointment of Zoladex should be excluded from patient pregnancy, and during the treatment should use non-hormonal methods of contraception.

Side effect

In drug treatment, many women complain of the emergence of "hot flashes", sweating and loosening of sexual desire. In some cases, possible headache, unstable mood, dryness of the vaginal mucosa, a change in breast size. In addition, prolonged use of Zoladex results in demineralization of bone, it is dangerous to the development of osteoporosis.

Anna Sozinova