- Polyps in the uterus - the result of hormonal disorders
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- Causes
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Causes of polyps in the uterus
In spite of the great possibilities of modern medicine, the introduction of new technologies, we can not speak of a unified theory of the development of polyps. Polyps in the uterus reason consists of several predisposing factors, the presence of which can be detected after a comprehensive examination of the patient. Diagnostic value of hormonal disorders have transferred inflammatory diseases, as well as intra-uterine manipulation.
Polyps in the uterus - benign growths in the lining of the uterus (the endometrium). Under normal circumstances, growth of the endometrium is terminated before the onset of menstruation (lining of the uterus peels off and leaves with menstrual blood). In some cases, there is an abnormal growth of the endometrium - the formation of uterine polyps. In the process of proliferation of polyps grow in size and attach to the lining of the uterus thin legs, resembling in its structure branched shrub or tree. Usually the size of the polyps in the uterus does not exceed a few centimeters, and only in rare cases, they grow to the size of an orange.
The cause of uterine polyps
Although the exact cause of polyps growths in the uterus is not known, the occurrence of uterine polyps can be either spontaneous or the result of too high levels of the hormone estrogen. Hormonal activity and an increase in estrogen levels - one of the most common causes of polyps in the uterus: uterine polyps can grow faster during pregnancy, during hormone replacement therapy or regular oral contraceptives, which contain synthetic hormones.
Polyps in the uterus that occur before menopause, usually completely harmless and does not lead to cancer of the uterus, but in the case of uterine polyps, sprawling in menopause or after menopause, there is a risk of turning them into malignant (carcinogenic) education.
In most cases, however, growth of polyps in the uterus is stopped with the onset of menopause, when estrogen levels
Estrogen - the key to bone health
reduced - which supports the theory that the main cause of polyps in the uterus - this is hormonal activity. Polyps in the uterus are more common in middle age - the peak of proliferation of uterine polyps to the period before menopause and after menopause abnormal proliferation of the endometrium usually slows down and stops completely.
Another possible cause of polyps in the uterus - a violation of the natural mechanism of proliferation of the endometrium (lining of the uterus). In the course of the menstrual cycle - the lining of the uterus grows gradually, as happens in a woman's preparation for the implantation of a fertilized egg. Lack of fertilization leads to peeling of the mucous in the menstrual period. Sometimes, as a result of hormonal imbalance is too great proliferation of mucosa, causing the formation of small lumps - uterine polyps.
Effect of past infection
There has been a growing number of diseases of the pelvic inflammatory nature. The reason for their development can not only be conditionally pathogenic, and infection that can be transmitted sexually. Chronic inflammation leads to a change in the state of the mucous membrane, which can be a starting point for focal hyperplasia
Hyperplasia - do not be afraid
and endometrial polyps. If inflammatory processes occur on the background activity of the unmodified hormone, the menstrual cycle will be saved. It will violated rejection of the functional layer of the endometrium, or at some particular area of inflammation as a result of suffering, which ultimately will cause the formation of polyps. You can talk about the predisposition to the development of polyps after endometritis, which has a complicated, chronic course.
Contributing factors are intrauterine manipulations are complicated by inflammation. It can be produced after curettage of the uterus
Curettage - how dangerous it is?
. To prevent the development of pathological changes in the mucous membrane of the uterus, it is recommended to conduct a full course of anti-inflammatory therapy with subsequent remedial actions at the stage of rehabilitation.
Changes in hormonal relations
The primary causal factor in the development of polyps is considered a hormonal imbalance. This is manifested as impaired production of sex hormones ratio throughout the menstrual cycle. To diagnose changes in hormone ratios can be based on the results of a blood test, it should be taken into account in the figures, depending on the phase of the cycle of women:
- estradiol levels
- progesterone levels
- of central hormones (LH and FSH)
It is impossible to determine the content of sex hormones selectively or in different menstrual cycles. Hormones ratio should be determined in one cycle for the entire cycle three times (in phase 1 and 2, in the ovulatory period). Only on the basis of such a comprehensive examination can reveal the true cause of hormonal diseases.
Dishormonal disorders may be a sign of active growing cells in response to an excess concentration of hormones in the blood.
Such violations often lead to the appearance of glandular polyps, combined with signs of endometrial hyperplasia
Hyperplasia endometrial cancer - requires timely detection and treatment
. It hyperplastic mucosal cells form the basis of glandular polyps with advanced glands. This explains why it is necessary to appoint a timely hormone therapy and spend it in full for several months.
Hormonal imbalance can manifest itself not only a violation of the production of sex hormones, as well as changes in sensitivity to them receptor system. The damage occurs at the receptor level after inflammatory diseases instrumental intervention within the uterine cavity. Treatment of hormonal agents will not sufficiently effective. Modern methods of diagnosis reveal the reason for this, so not all cases of endometrial polyposis should be hormonal therapy.
In some cases, it noted the existence of familial predisposition to the development of neoplastic processes that occur in the uterus hyperplasia, the formation of polyps. It proved the impact of restructuring shoulder certain chromosomes, which affects the origin of stromal cells of polyps. In some cases, may be a combination of several reasons why it should be taken into account in the process of diagnosis, to conduct a comprehensive examination, it does not exclude the possibility of the two causes of the disease at the same time.
Risk factors
According to statistics, in ten to twenty-five percent of all women in this or that period of life there are uterine polyps, which, however, in most cases disappear on their own with the normalization of hormonal levels. The risk of proliferation of polyps increases with age - most of the polyps in the uterus observed in women aged forty and older. Uterine polyps are very rare in women under the age of twenty years and over fifty years. Major risk factors that increase the likelihood of proliferation of polyps in the uterus - high blood pressure, obesity, and receive specific medical drugs prescribed for the treatment of breast cancer.