Infertility refers to one of the most serious problems that can disturb the couple. The causes of infertility are numerous. It may be inflammatory diseases of the genital organs, as a woman and a man, chronic physical illness and more. The lion's share of the kinds of infertility take endocrine problems. Accordingly, endocrine infertility can and should be treated with hormones. But infertility treatment with hormones in the first place depends on the cause that led to the endocrine pathology. Despite the fact that many women are opposed to the negative hormone, a similar treatment of endocrine infertility has positive results in most cases of interest.

Different types of endocrine infertility

Hormone treatment individually in each case of endocrine infertility:

• Hyperprolactinemia

Hyperprolactinemia is characterized by elevated blood levels of the hormone-prolactin. It causes hyperprolactinemia, include pituitary tumors, brain trauma, receiving a variety of medications, fasting, and more. When hyperprolactinemia disturbed menstrual function, until the development of amenorrhea, and is separated from the breast milk. Treatment of hyperprolactinemia is the appointment of Parlodel (bromocriptine), which normalizes prolactin levels. Dose of 2, 5-7 and 5 mg a day for six to eight menstrual cycles.

• Sclerocystic ovarian syndrome (Stein-Leventhal's disease)

The syndrome is characterized by obesity sclerocystic ovaries, menstrual irregularities, infertility, acne and hirsutism. Conservative therapy is the appointment of hormones. In the first stage normalize menstrual function cyclic hormone therapy (combined oral contraceptives) over three to six months. Further treatment aimed at Gaumont stimulation of ovulation, which is held klostilbegitom or gonadotropins (Menopur, purigon, Gonal-F).

• The lack of the luteal phase of the cycle

The main manifestations of insufficiency of the luteal phase of the cycle is infertility and scanty bleeding for four or five days before menstruation. The lack of the luteal phase of the cycle may develop as a result of dysfunction of the hypothalamic-pituitary system, hyperandrogenism, hyperprolactinemia, pathology yellow body and so on. Treatment begins with the appointment of hormone replacement therapy, ie progesterone ten days before menstruation. Sometimes appointed combined estrogen Estrogen - the key to bone health -gestagennye drugs for two to three cycles for the purpose of so-called rebound effect. After the restoration of the menstrual cycle, ovulation stimulation is performed klostilbegitom from the fifth to the ninth day of the cycle at a dose of 50 mg.

• Hyperandrogenism adrenal genesis

Clinically, the disease is manifested masculine physique, hirsutism, menstrual dysfunction, and infertility. When adrenal genesis of hyperandrogenism treatment is aimed at normalizing the function of the adrenal glands. For this purpose, appointed glucocorticoids, e.g., dexamethasone Dexamethasone - one of the most effective glucocorticosteroids Dose depends on androgen levels (0, 25-0, 5 mg per day controlled nature of the menstrual cycle and dynamics of basal temperature). If this treatment does not cause ovulation Ovulation - How to determine as accurately as possible? , Is added to the circuit klostilbegit 50-75 mg per day for five days.

• Thyroid disease

Thyroid disease characterized by the appearance of weakness, palpitations, sweating, sleep disturbances Dreams: how to understand our dreams , Nervousness, apathy, increase or decrease in body weight, feeling of heat, as well as menstrual dysfunction, and infertility. Recovery of thyroid function with the help of thyritropic and other hormones leads to normalization of the menstrual cycle and fertility restoration.

• Adiposity

Overweight is also one of the causes of endocrine infertility. Treatment is to normalize weights assigned special diet and exercise, as well as the administration of hormones.

Anna Sozinova

Uterine fibroids - a benign tumor of muscle layer of the uterus, the main cause of which is a violation of hormonal background. Contribute to the development of uterine fibroids, and it featured a variety of diseases and injuries, including abortion and severe traumatic birth. Matter also severe neuro-psychological and physical stress.

Types of fibroids

Uterine fibroids - a benign tumor in the form of units of various sizes in the muscle layer of the uterus grows it for a long time, for years. Therefore, the first signs of the disease can occur when the tumor reaches a considerable size. But this is not always the case. Disturbances in hormonal levels, manifested in the form of menstrual disorders, can "give" even a small fibroids.

It may be:

• submucous situated directly beneath the inner mucosa of the uterus, - in this case, the tumor grows inside the uterine cavity;
• subserous situated under the outer layer of the uterus - the tumor growth is in the pelvic cavity;
• interstitial situated deep in the muscle layer of the uterus;
• cervical - located in the muscular layer of the cervix.

Fibroids may be small, medium and large sizes.

Uterine fibroids - signs of trouble

The main signs of uterine fibroids are menstrual disorders, abdominal pain Abdominal pain: when to sound the alarm?   and in the lower back, and organ dysfunction, the growing uterus compresses.

Menstrual disorders are manifested as menorrhagia and metrorrhagia. Menorrhagia - a heavy prolonged menstrual bleeding, and metrorrhagia - uterine bleeding Uterine bleeding outside of menstruation - a sign of a serious breach Not related to the menstrual cycle. The duration and intensity of bleeding may increase, it leads to chronic blood loss and iron-deficiency anemia.

Pain in the abdomen and in the lumbar region are usually aching and swelling of the nature of time. But sometimes the pain can be very powerful - it's usually associated with malnutrition tumor when she pinched her nourishing blood vessel. Pain may increase as during sexual intercourse, and various gynecological procedures, including the examination of the gynecologist.

The function of the uterus adjacent to the changes mainly in the form of subserous fibroid which grows inside the pelvis. If such a tumor grows in the direction of the urethra, then sooner or later it will lead to voiding. Stagnation of urine in the urinary tract can lead to the formation of stones, or to join an infection - develop acute and chronic cystitis and pyelonephritis.

If the tumor grows in the direction of the rectum, the disturbed defecation, there are persistent constipation, foreign body sensation in the anus, and sometimes the pain if compressed nerve endings, which in the rectum very much.

Complications of uterine fibroids

The most common complication of uterine fibroids is a long-term flows and can not be correct iron deficiency anemia. That the symptoms of anemia worried woman most. Symptoms of iron deficiency anemia is a pale skin, weakness, drowsiness, constant malaise, chilliness, decreased performance. Such joining of constant headaches and dizziness, sometimes - fainting, due to the violation of blood supply to brain tissue.

Fibroids often quite thin legs, which squeezed the tumor itself or twisted - it causes severe pain and swelling malnutrition. This state is very dangerous because it can lead to necrosis of the tumor that will require immediate surgery.

Compression of the tumor to adjacent organs leads to the development of pyelonephritis, cystitis, urolithiasis Kidney stones - why women tolerate it harder?   and impaired renal function. Squeezing the rectum leads to digestive disorders, cracks in the anus, blood circulation in the rectal area and the development of infections in the form paraproctitis (inflammation in the area adjacent to the rectum of fiber).

Uterine fibroids may also be as a threat to pregnancy and childbirth. In most cases this can be avoided, however, impaired fertility can be at any stage, since conception (if uterine opening of the uterine tube compresses and prevents it spermatozoa) and ending with delivery.

Uterine fibroids is quite characteristic signs when they appear, a woman should see a doctor immediately.

Galina Romanenko