Nicotinic acid (vitamin PP, vitamin B3) is widely used in the treatment of various diseases, as it influences the metabolism
Metabolism: The basis of life of all living things
(increasing the rate of redox reactions) - the mechanism that underlies any disease.
Use of nicotinic acid in pellagra
Pellagra - a disease associated with insufficient intake of or incomplete assimilation of nicotinic acid and tryptophan. There she mainly in those countries where the staple food is maize and the population almost does not use animal protein. The maize also contains the amino acid leucine, hampering the body's co-enzymes, which include nicotinic acid
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. When the disease affects the gastrointestinal tract (diarrhea, inflammation of the tongue), the skin (redness, swelling, itching), and central nervous system (dementia).
Nicotinic acid or nicotinamide in this disease is prescribed orally at high doses, 100 mg 3 times a day half an hour after a meal for 2 - 3 weeks.
The use of nicotinic acid in diseases of the digestive system
Admission into nicotinic acid stimulates the secretion of gastric juices, so it is always prescribed for gastritis with decreased secretion.
But in other gastrointestinal disease in remission (non-acute) nicotinic acid also shows, as it expands the small blood vessels and promotes a rush of blood to the internal organs. As a result, in the gastrointestinal tract improving metabolism
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That promotes healing or lengthening the period of remission. Nicotinic acid is used in gastritis, gastroduodenitis, stomach ulcer and duodenal ulcer, chronic pancreatitis, enterocolitis and colitis.
Do not take niacin inside with acute gastric ulcer and duodenal ulcers, as it stimulates the secretion of gastric juice, which will increase the pain and other symptoms of the disease. Additionally, vasodilation of the stomach can cause stomach bleeding.
Nicotinic acid is used in the case when it comes into contact with food in sufficient quantity, but for some reason can not be assimilated. This occurs, for example, malabsorption syndrome when disturbed absorption of food in the small intestine. This may be due to various reasons, for example, after removal of the stomach, liver and pancreas
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In diseases of the liver and biliary tract also prescribe niacin - it promotes better blood supply to the liver cells, improve its metabolism and increase the biliary tract, which prevents stagnation of bile. Do not use nicotinic acid long, more than a month - it can lead to abnormal liver function. It is not necessary to use it, and in severe liver disease with persistent violations of its functions.
Use of nicotinic acid in cardiovascular diseases
Niacin has a positive effect on the metabolism and reduces the effects of atherosclerosis, against which developed such severe cardiovascular diseases such as coronary heart disease (CHD), cerebral ischemia and arterial occlusive disease. The cause of these diseases - blockage of the arteries feeding the bodies of atherosclerotic plaques.
Use of nicotinic acid in atherosclerosis and related diseases of the cardiovascular system improves during these diseases and prevents the formation of new atherosclerotic plaques. However, in severe forms of arteriosclerosis and high blood pressure consistently designate nicotinic acid should be cautious, and its intravenous administration is contraindicated. Danger intravenous and intramuscular administration of nicotinic acid, and low blood pressure.
The use of nicotinic acid with weak healing wounds and trophic ulcers
When weak healing wounds the use of nicotinic acid causes a rush of blood to the pathological focus, that improves nutrition of the affected tissues, improves metabolic processes in them, and contributes to activation of regenerative processes. In this case, nicotinic acid is often administered intramuscularly or even intravenously.
Sores often occur on the background of varicose veins, which is accompanied by increased blood clotting and a tendency to form blood clots. Niacin contributes to not only a rush of blood and activation of metabolic processes, and blood thinners, which to some extent prevents clot formation and further improve the course of disease. Therefore, trophic ulcers and nicotinic acid in the case of courses administered as a oral and intramuscular.
Niacin is an excellent treatment for many diseases. It can also be used as stand-alone courses, and as a part of complex treatment.