Heparin ointment - a drug for external use which prevents thrombosis, anti-inflammatory and analgesic action of light. Assign heparin ointment at the local manifestations of thrombosis in a limb thrombophlebitis, hemorrhoids, and after injuries.

The mechanism of action of heparin ointment

Heparin ointment has a combined composition and used as external and local funds. The structure of heparin, heparin ointment includes, benzyl, and benzocaine (1 g of ointment containing 100 units of heparin sodium, 0, 8 mg and 40 mg of benzyl benzocaine).

Heparin - is an anticoagulant of direct action, anti-inflammatory, anticoagulant effect, helps relieve swelling and prevents proliferation (tissue growth). When applying the ointment to the body surface heparin gradually absorbed into the bloodstream and activates antithrombin III (protein having anticoagulant effect). This leads to disruption of the conversion of prothrombin to thrombin, the thrombin inhibits, reduces the degree of aggregation (ability to stick together, forming multicellular formation) platelets.

In addition, heparin inhibits the blood's ability to form fibrin, which is the basis of blood clots and slightly reduced local immunity tissues. He is also able to dissolve already formed clots, improve blood circulation in small blood vessels, stimulates metabolism Improves metabolism and losing weight without dieting   in tissues which promotes more active resorption of haematomas and blood clots and reduce edema.

Benzyl - vasodilator that improves absorbability of heparin and benzocaine - a local anesthetic that reduces the sensation of pain.

All three are part of a heparin ointment formulation together ensure antithrombotic, anti-inflammatory and local anesthetic action.

Indications for use of heparin ointment and the method of its application

Heparin ointment used in thrombophlebitis - inflammation of the walls of superficial veins, which is accompanied by thrombosis. Thrombophlebitis dangerous because the infection can spread through the veins, malnutrition surrounding tissue can lead to necrosis. But the main danger is the separation of thrombophlebitis clots and emboli occlusion of large blood vessels. Especially dangerous thromboembolism Thromboembolism: severe complications   pulmonary artery, it can cause instantaneous death of the patient. When thrombophlebitis of superficial veins in the complex treatment administered heparin ointment which prevents the formation of blood clots, dissolves already formed clots, reduces inflammation in the walls of the veins and the pain in that area.

Inflammation of the veins may begin after intravenous injection - in this case heparin ointment is desirable to apply as early as possible - it will remove the inflammation, reduce pain and prevent the formation of blood clots. When hematoma formed after injury, heparin ointment is applied with a view to their early resorption.

In all these cases, heparin ointment is applied in a thin layer (less than 1 g on the area of ​​3-5 cm in diameter) on the surface of the skin and rub gently. The procedure is performed two or three times a day.

Hemorrhoids is a stagnation of venous blood in the rectal area. Venous thrombosis in this field leads to the appearance of symptoms of acute hemorrhoids: severe pain, which give crotch and amplified during defecation. Malnutrition causes tissue necrosis and pitting them. Such a process is almost always associated infection that can lead to severe septic complications. For the treatment of hemorrhoids are also used heparin ointment that relieves swelling of the tissues, reduces blood clots, prevents the formation of new blood clots. This ointment is also actively reduces inflammation and pain in the area of ​​acute hemorrhoids.

In acute hemorrhoids Acute Hemorrhoids - office workers at risk   is introduced into the rectum swabs How to use sanitary pad - basic precautions Impregnated with heparin ointment. Procedures are carried out once a day for no more than two weeks.

Contraindications for use

Contraindications to the use of heparin ointment is a violation of the integrity of the tissue in the area of ​​thrombosis or acute hemorrhoids - it can lead to bleeding. It can not be applied on open sores. It can lead to bleeding and the use of heparin ointment on the background of reduced blood coagulation and thrombocytopenia (decrease in the number of platelets in the blood). Of course, you can not use heparin ointment in case of hypersensitivity to its components of the patient.

Side effects of heparin ointment only known allergic reactions.

Heparin ointment can prevent or greatly facilitate for various diseases associated with thrombosis.

Galina Romanenko

  Hemophilia - a rare hereditary disorder in which impaired coagulation, or clotting. After any injury bleeding in patients with hemophilia lasts much longer than in healthy people. They often develop internal bleeding, particularly in the joints.

In some cases, hemophilia is purchased - it occurs when the body produces antibodies Antibodies - "soldiers' immunity   to coagulation factors.

In newborns with hemophilia protein necessary for normal blood clotting is missing or is at a very low level. These proteins are called coagulation factors.

Hemophilia, with very few exceptions, is found only in men.

What is blood clotting

Trauma (eg, cut) of a blood vessel triggers a complex chain of events that result in blood clotting. Coagulation - a reaction to bleeding, which prevents the loss of too much blood. Most blood loss can be life-threatening, and often causes damage to internal organs.

What is the coagulation factor

Coagulation factor is a group of substances, especially proteins, which work with platelets Platelets - what they are for the body? Helping blood to clot. When damaged blood vessels clotting factors help the platelets combine with each other to close those sites that have been damaged.

People with hemophilia blood does not clot quickly enough, as clotting factors have no, or very little. This can lead to greater blood loss and / or damage to the organs and tissues of the body. The result could be permanent damage or death of the patient. To stop the bleeding, hemophilia may need to enter the coagulation factors.

Types of hemophilia

There are two main types of hemophilia:

• Hemophilia A - is characterized by the absence or low levels of clotting factor VIII. Approximately 9 out of 10 people with hemophilia are diagnosed with this type of hemophilia.
• Hemophilia B is characterized by the absence or low levels of clotting factor IX.

Hemophilia can be mild, moderate, or severe, depending on the amount of blood coagulation factor. About 7 of the 10 persons with hemophilia A suffer from severe forms of the disease.

Causes

Hemophilia - a hereditary disease. It is caused by a defect in the genes that determine how the body makes blood clotting factors VIII and IX. These genes are located on the X chromosome.

If a woman has this defective gene ("hemophilia gene"), she can pass it on to their children. If she has a son, the likelihood that he will get sick with hemophilia, is 50%. When my daughter was born the likelihood that it will become a carrier of the hemophilia gene is also 50%.

A man with hemophilia, can not transmit the disease to his sons, but all his daughters will be carriers of hemophilia.

Very rarely girls are born with haemophilia. This can happen if her father had hemophilia and her mother is a carrier of the hemophilia gene.

Sometimes boys are born with hemophilia in women who are not carriers of the defective gene. In such cases, the genes are transferred child mutations occur, which is practically impossible to anticipate.

Symptoms

The main symptoms of hemophilia are frequent bruising, bruising and prolonged bleeding. Internal bleeding is common in people with severe hemophilia. Without rapid treatment of internal bleeding could result in damage to the joints, muscles or other body parts.

Most young children first signs of hemophilia are excessive bleeding during teething Teething: hard times , Bruising and bruising from even minor injuries, swelling in the joints, which can be caused by internal bleeding. In older children and adults, besides those already mentioned, the following symptoms of hemophilia: nosebleeds for no apparent reason, the presence of blood in urine Blood in the urine - a reason for serious concern   (caused by bleeding in the kidney or bladder) and stool (caused by bleeding in the gut or stomach).

Bleeding in the joints - the most common problem of patients with hemophilia. Often bleeding begins a result of trauma and without treatment can continue for several days. However, people with haemophilia, learn to recognize early symptoms of hemophilia, and, as a rule, during seek medical help.