Sorbifer durules - combined drug protivoanemicheskim

February 28, 2010

  • Sorbifer durules - combined drug protivoanemicheskim
  • Mechanism of action

 corbifer durules
 The active ingredients are Sorbifer ferrous sulfate and ascorbic acid. Iron plays an important role in the production of hemoglobin, the substance in the red blood cells needed to transport oxygen. This provides an adequate oxygen supply of all body parts.

Iron stored in the body as ferritin; its main sources in the diet are meat and liver. When iron deficiency develops iron deficiency anemia.

Ascorbic acid (vitamin C) - a powerful antioxidant Antioxidants: the truth about the notorious benefits  Antioxidants: the truth about the notorious benefits
 Which can be obtained from citrus fruits and some vegetables. The body uses its structural protein binding - of collagen, which provides support for a variety of body tissues. Deficiency of vitamin C can cause a variety of violations, including - scurvy Scurvy: a rare but dangerous  Scurvy: a rare but dangerous
 .

Ascorbic acid composition Sorbifer not only improves the absorption of iron but also fills the shortage of vitamin C.

 Sorbifer durules - combined drug protivoanemicheskim

Indications

Prevention and treatment of iron deficiency anemia in people who are also experiencing a shortage of vitamin C.

 Sorbifer durules - combined drug protivoanemicheskim

How to take Sorbifer

It is recommended to take one tablet a day Sorbifer or as advised by the doctor. It should be taken before meals, on an empty stomach. However, if Sorbifer cause stomach upset, it may be administered with food or immediately after meals.

Tea, coffee, eggs and milk can reduce the absorption of iron. Avoid the consumption of these products while taking Sorbifer.

Take tablets Sorbifer whole, do not chew and grind them in other ways.

 Sorbifer durules - combined drug protivoanemicheskim

Attention!

During the reception Sorbifer chair can be much darker than usual. This is normal and should not cause concern.

Keep out of the reach of children - it contains iron overdose can be lethal for children.

This drug may cause false negative result of the analysis for the presence of sugar in urine.

 Sorbifer durules - combined drug protivoanemicheskim

Contraindications

Contraindications to the use Sorbifer are:

  • Anemia caused by a deficiency of vitamin B12 (pernicious anemia);
  • Anemia caused by folic acid deficiency;
  • Hemochromatosis - a genetic disorder that leads to the deposition of excessive amounts of iron in the body;
  • Hemosiderosis;
  • Paroxysmal nocturnal hemoglobinuria;
  • Violations related to hemoglobin, such as sickle cell anemia or thalassemia;
  • People who repeatedly blood transfusions;
  • Active peptic ulcer;
  • Inflammatory bowel disease, e.g., ulcerative colitis and Crohn's disease;
  • Age 12 years.

Admission Sorbifer during pregnancy and breast-feeding is allowed only with the permission of the doctor.

In addition, Sorbifer not take people who are allergic to any of its components. If signs of an allergic reaction while taking Sorbifer should consult a doctor.

 Sorbifer durules - combined drug protivoanemicheskim

Side effects

Most often Sorbifer cause the following side effects:

  • Abdominal pain;
  • Constipation;
  • Diarrhea;
  • Nausea and vomiting;
  • Lack of appetite;
  • The dark color of the chair.

Typically, these side effects are very soft and do not cause anxiety in the patient and tested soon after discontinuation of the drug.

 Sorbifer durules - combined drug protivoanemicheskim

Drug Interactions

Formulations containing iron, can affect the absorption of certain drugs reduces their effectiveness. For this reason, it is necessary that between receiving and Sorbifer any medication takes at least two hours. This applies, in particular, the following drugs:

  • Bisphosphonates, such as alendronate;
  • Entacapone;
  • Levodopa and carbidopa;
  • Levothyroxine;
  • Methyldopa;
  • Penicillamine;
  • Quinolone antibiotics such as ciprofloxacin, norfloxacin, ofloxacin, levofloxacin;
  • Tetracycline antibiotics, such as oxytetracycline, doxycycline Doxycycline - penetrates into the tissue cells  Doxycycline - penetrates into the tissue cells
 , Minocycline, tetracycline Tetracycline - a natural broad-spectrum antibiotic  Tetracycline - a natural broad-spectrum antibiotic
   (These antibiotics also reduce iron absorption from the gut).

Moreover, absorption of iron may deteriorate additives with zinc and calcium, as well as antacids (drugs used to treat heartburn).

Vitamin B12: saves from anemia

November 18, 2011

 Vitamin B12
 The human body is very sensitive to the slightest violation of the delicate balance. A balanced diet provides the body with the necessary amount of vitamins, minerals and other nutrients that we need for normal life. Everybody knows about the benefits and importance of vitamins, especially vitamin B12.

Vitamin B12 is involved in hematopoiesis, regulates carbohydrate and fat metabolism in the body. With its lack develops anemia - anemia.

 Vitamin B12: saves from anemia

Main functions

Vitamin B12 plays extremely an important role in the proper functioning of the nervous system, thus affecting on the operation of all organs. If the body lack of vitamin B12, it also leads to a deficiency of vitamin B1, even when seemingly enough in his diet. This leads to frustration, not only the nervous system, and endocrine glands, brain disease beriberi (polyneuritis), violation of the digestive system.

Psychiatrists are often surprised by how quickly helps in some cases, patients with vitamin B12. In addition, it alleviates pain in the eyes, sometimes treating infertility, particularly in men.

Vitamin B12 is involved in cell division, inherent in every living cell. The most adequate level of vitamin B12 dependent those tissues that fall most heavily: red blood cells, immune cells, skin cells, and cells lining the intestines. Although its mechanism of action is not entirely clear, it is known that vitamin B12, plays a critical role in the formation of the coating of nerves (called myelin sheath itself as a proteinaceous material called myelin) and chronic failure it causes irreversible destruction of nerves.

 Vitamin B12: saves from anemia

Participation of vitamin B12 in metabolic processes

This vitamin is actively involved in the metabolism of proteins, fats and carbohydrates in close cooperation with vitamin C, folic and pantothenic acids. To have been healthy nerves and we were fully prepared to everyday stress, vitamin B12 helps billions of molecules of folic acid in the development of choline. It updates the iron stores in the body, which is usually not enough, and provides entry carotene metabolism Metabolism: The basis of life of all living things  Metabolism: The basis of life of all living things
   and their conversion to active vitamin A. Finally, in conjunction with other substances vitamin B12 launches basic life process - the synthesis of deoxyribonucleic and ribonucleic acids. It proteins that make up the cell nucleus and which contain all the genetic information.

This water-soluble vitamin found in dairy products, egg yolks, meat, liver, kidney and fish. The content of vitamin B12 in the blood low in people suffering from Alzheimer's disease and some other psychiatric disorders.

Vitamin B12 has many important functions in the body. Together with the molecules of folic acid vitamin B12 is involved in the production of choline. It updates the iron stores in the body, which is usually not enough, and provides entry carotene metabolism Improves metabolism and losing weight without dieting  Improves metabolism and losing weight without dieting
   and their conversion to active vitamin A. Finally, the interaction with other substances, vitamin B12 launches basic life process - the synthesis of deoxyribonucleic and ribonucleic acids.

Unfortunately, many people suffer from a deficiency of this essential vitamin for health.

 Vitamin B12: saves from anemia

Causes of vitamin B12 deficiency

Deficiency of vitamin B12 in the body can be caused by various factors. It generally develops in people with disorders of the digestive system that prevent the normal absorption of vitamins. This may be caused by the following reasons:

  • Pernicious anemia, which is accompanied by fatigue, weakness, burning tongue, stomach diseases caused by lack of gastric juice, difficulty walking, pain in the legs. It is difficult to understand how one could deliver the vitamin directly from all these hassles. In the early twentieth century, pernicious anemia was considered an incurable disease, she was treated as a type of cancer. However, on the island of Sri Lanka (Ceylon) for centuries treated pernicious anemia raw liver.
  • Atrophic gastritis (thinning of the gastric mucosa) that affects more than 30% of people over 50 years.
  • The consequences of surgical removal of the stomach or intestines.
  • Diseases that affect the small intestine, in particular Crohn's disease (chronic granulomatous inflammation of the gastrointestinal tract), celiac disease (malabsorption of food as a result of diseases of the small intestine, which leads to intolerance glyuteina) multiplication of bacteria or parasites.
  • Alcoholism.
  • Autoimmune diseases such as Graves' disease Graves' disease - when the immune system breaks down  Graves' disease - when the immune system breaks down
   or systemic lupus.
  • Long reception of medicines, reducing acidity.

Birth control pills and a large number of different medications can deplete the entire stock of vitamin B12 .  Furthermore, to assimilate it is necessary a special substance, the so-called intrinsic factor, which is produced in the body and stored in the gastric juice .  Without it, even the largest number of vitamin B12 is poorly absorbed .  There are people in the body of which he is not synthesized .  This applies mostly to elderly people, whose digestive system reduces the release of certain acids (eg, hydrochloric acid) .  If acid is not allocated in the required amount, then the substance is not synthesized, and then the iron and vitamin B12 are absorbed worse, which may lead to anemia .  In such cases, the best results give an injection of vitamin B12, not pills, which are also difficult to reconcile with iron .  However, acid berries, fruits, vegetables, apple cider vinegar maintain the desired level of acidity in the body .  Therefore, we must constantly ensure that the body receives adequate amounts of vitamins B1, B6, B2 and B12, along with natural products .

The minimum daily intake of 3 g. Even if we eat very little meat, milk and eggs, we give the body about 15 micrograms of vitamin B12. Only pure vegetarians are at risk of losing it, so they need to take supplements of vitamin B12. Also, vitamin B12 deficiency is frequently observed in newborns if their mother - a vegetarian.

 Vitamin B12: saves from anemia

Symptoms of vitamin B12 deficiency

Vitamin B12 deficiency can lead to B12-deficiency anemia, which initially asymptomatic, but with time takes on the following characteristics:

  • weakness, fatigue, or dizziness;
  • rapid heartbeat and breathing;
  • pale skin;
  • inflammation of the tongue;
  • bleeding gums;
  • diarrhea and weight loss;
  • diarrhea or constipation.

Symptoms of deficiency also includes:

  • disorders of the gastrointestinal tract;
  • heart rhythm abnormalities;
  • impaired coordination of movements;
  • memory loss;
  • hallucinations;
  • depression;
  • visual disturbances;
  • the destruction of the nervous system and spinal cord.

In infants and young children vitamin B12 deficiency in the absence of timely treatment can cause permanent damage to the nervous system.

 Vitamin B12: saves from anemia

Treatment of vitamin B12 deficiency

Treatment of vitamin B12 deficiency depends on its cause. If it is called pernicious anemia or malabsorption of nutrients necessary replacement of vitamin B12 by injection or taking vitamin supplements Food additives - basic classification  Food additives - basic classification
 .

In some cases, supplements of vitamin B12 must be taken throughout life. It occurs when the patient does not consume animal products, such as a vegan or vegetarian.

In most cases, the treatment helps to eliminate the deficiency of vitamin B12, but disorders and nervous system damage caused by this deficiency are irreversible.

 Vitamin B12: saves from anemia

Prevention of vitamin B12 deficiency

For the prevention of vitamin B12 deficiency is enough to eat normally and to include in the diet of dairy products, egg raw egg yolk, soy, yeast, baker's and brewer, lettuce, green onions, beef, veal and pork liver or a liver pate (a small piece of vegetables, which should be 3 times more than the liver or liver pate), spinach and seafood - sea kale, squid, shrimp.

The need for vitamin B12 is increased by the use of alcohol and smoking. If you need additional reception of vitamin B12, aim to eat more foods rich in this substance. Supplementation of vitamin B12 is justified only in the case where it fails to fill the deficit only through changes in diet.


Article Tags:
  • B vitamins




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