The cure for TB - is, above all, anti-bacterial agents. Moreover, in the complex treatment of patients with tuberculosis include immunomodulators, pathogenetic (suppressive mechanism of tuberculosis), symptomatic and some other tools.

Antibacterial drugs for the treatment of pulmonary tuberculosis

To antibiotics for the treatment of tuberculosis Treatment of tuberculosis - a lengthy process and requires constant monitoring   lungs are synthetic chemical drugs (drugs of gidrazidizonikotinovoy acid, pyrazinamide, tiamidy, p-aminosalicylic acid and ethambutol), acting only on the Mycobacterium tuberculosis (MBT) and antibiotics (aminoglycosides, polypeptides, rifamycins, cycloserine and fluoroquinolones) with a broad spectrum of antimicrobial activity, not only in the ILO but also non-specific pathogens. It may be a pill for the treatment of tuberculosis or injections.

Moreover, antibacterial drugs to treat tuberculosis are divided into basic (they start to treat newly diagnosed TB) and reserve (they are used in the case where the core group of drugs can not be applied, such as insensitivity to him ILO).

Antibiotics to treat tuberculosis from the main group of anti-TB drugs - a rifamycin antibiotics (rifampicin, rifabutin) and aminoglycosides (streptomycin).

Reserve antibiotics in pulmonary tuberculosis - is antibiotics aminoglycoside kanamycin and amikacin, an antibiotic from the group of polypeptides capreomycin, cycloserine and antibiotics fluoroquinolones (lomefloxacin, ciprofloxacin, ofloxacin, levofloxacin and moxifloxacin).

A major problem in the treatment of drug tuberculosis is Tuberculosis - a full recovery is not guaranteed . Tubercle bacillus may exhibit resistance (resistance) in relation to one, two or more drugs, including the commonly prescribed and effective combination of drugs isoniazid and rifampicin. The cause of secondary drug resistance of tubercle bacilli to anti-TB drugs are gene mutations that arise in the event that a cure for tuberculosis was prescribed incorrectly. But meets and primary drug resistance to TB drugs. Treatment of such patients is appointed only after a preliminary study on the drug susceptibility of Mycobacterium tuberculosis. Assign a combination of individually selected primary and backup TB drugs (at least five drugs), which maintain the sensitivity of infectious agents, for a period of six months.

For the treatment of drug-resistant forms of TB is also used pills for tuberculosis perhlozon - A new anti-TB drugs with exactly unknown mechanism of action.

Antifungal drugs for tuberculosis

Active and prolonged use of antimicrobials leads to suppression of the natural microflora inhabiting the skin and mucous membranes of the patient. And this in turn leads to a proliferation of pathogenic microflora, including fungi genus Candida. To suppress their ability to live together with antibiotic therapy administered antifungal agents, most often it is fluconazole Fluconazole - used with caution .

Immunomodulators tuberculosis

Application TB and certain inflammatory and antiallergic agents (e.g., glucocorticoids) leads to reduced immunity. Therefore, in the complex treatment of tuberculosis almost always include immunomodulators - drugs that restore immunity.

Assign immunomodulators such as taktivin and timalin (prepared from the thymus gland of cattle), Timoptin (from the thymus gland of mammals). From the latest generation of drugs most often used leukinferon - a complex of natural interferons, has immunomodulatory, anti-inflammatory and detoxifying effect, activating cellular immunity and helps improve the tolerability of anti-TB drugs. Specific immunomodulatory tuberculosis is the tuberculin and BCG.

What other drugs used to treat tuberculosis

The structure of the complex treatment of patients with tuberculosis always prescribe vitamin and minerals. It used in tuberculosis Badam are Vetoron (vitamin complex) and Tsygapan (powder reindeer horns). Assign also zinc (zinc sulfate) - a trace element that participates in many enzymatic reactions, and enhances immunity Strengthening the immune system - help the immune system .

Medicines for pulmonary tuberculosis in our country provided to patients free when you register at the TB clinic.

Galina Romanenko

Vilprafen - is a highly modern antibacterial drug that has minimal side effects and contraindications for use. You can even assign pregnant women, in fact, the World Health Organization (WHO) recommends vilprafen as the antibiotic of choice for treatment of infections in pregnant women, caused by susceptible to antibiotics.

Why vilprafen no adverse effects on the body

Vilprafen (active substance josamycin) - a macrolide antibiotic that exhibits high efficacy against many infectious agents. Sensitivity to show him Staphylococcus aureus, many types of Streptococcus, meningococcus, gonorrhea, syphilis, chlamydia Chlamydia: insidious and widespread disease , Mycoplasma Mycoplasma - the smallest microbe , Ureaplasma and others.

This vilprafen almost completely non-toxic. This is due to the fact that the recommended therapeutic doses, it inhibits the proliferation of sensitive thereto pathogens by inhibiting protein synthesis in cells. Protein synthesis is impossible, since the newly formed cells is not transported RNA donor cells (bacteriostatic effect). In some cases, the inflammation a high concentration Wilprafen then inhibited protein synthesis in all cells of pathogens, causing them to die (bactericidal effect).

On host cells (human), which are parasitic infectious agents, vilprafen has no effect, which is why it has minimal side effects.

Side effects Wilprafen the gastro-intestinal tract

In most vilprafen it gives side effects of the gastrointestinal tract. This loss of appetite, heartburn, nausea, vomiting and diarrhea. In most cases, this minimal side effects that do not require discontinuation.

In applying Wilprafen in therapeutic doses to normal for a long course of antibiotics he usually has no adverse effects on intestinal microflora. However, chronic administration of high doses or in patients suffering from chronic diseases of the digestive system, as well as having long flowing infectious-inflammatory processes, requiring frequent administration of antibiotics (chronic bronchitis, tonsillitis, sinusitis, etc.) vilprafen Vilprafen - modern highly effective and non-toxic antibiotic   It can suppress the vital activity of beneficial intestinal microflora, which leads to proliferation of pathogenic microflora, insensitive to this antibiotic Antibiotics - whether they will help you in the foreseeable future? . As a result, there is a risk of dysbiosis, intestinal candidiasis and pseudomembranous colitis.

Dysbacteriosis - it is not a disease but predbolezn at which the breach relation between beneficial and pathogenic microflora of the intestine occurs digestive disorders with all the consequences: increased flatulence and pain during bowel, constipation alternating with diarrhea, and so on.

If the intestine actively proliferate fungi genus Candida, it leads to the development of the disease - candidiasis, which runs as a violation of the digestive process, but it is inflamed and the wall of the intestine, which is very dangerous. In addition, agents of intestinal candidiasis can spread to other organs.

Finally, long-term use Wilprafen may develop pseudomembranous colitis, which is also known as clostridium. The cause of this disease is a type of clostridia - Clostridium difficile, which are part of opportunistic intestinal microflora and practically do not show sensitivity to antibiotics. The peculiarity of these organisms is that they produce toxins that destroy the intestinal wall. The disease can occur easily and exhibit prolonged diarrhea, which take place after the abolition of antibiotics, and can be very difficult to heat, collapse, bowel perforation, and threatened the life of the patient. Therefore, the appearance of persistent diarrhea in patients receiving Wilprafen it is usually canceled.

Other side effects Wilprafen

Side effects from the liver when taking Wilprafen rare. This can manifest itself in the form of changes in laboratory parameters (increased blood levels of liver enzymes), and may develop intrahepatic bile stasis and jaundice, but after discontinuation of the drug all of these side effects are.

In addition, you may experience hearing loss, which also disappear after drug withdrawal. If you suspect an allergic reaction vilprafen usually overturned.

Vilprafen - is an effective and non-toxic drug, but antibiotics can suppress the natural intestinal microflora, so they can only appoint a doctor.

Galina Romanenko