Makmiror - is the trade name nifuratel - drug nitrofuran series that is effective against many pathogens that cause diseases of the gastrointestinal tract and urinary tract. A feature of nitrofurans is that microbial resistance to them develops slowly.

Medications nitrofuran series

To drugs - nitrofuran derivatives are many medications, both for external and local application (eg furatsillin) and oral (furadonin, furazolidone).

Nitrofurans oral used to treat various infectious and inflammatory diseases of the gastrointestinal tract, kidneys and urinary tract. These drugs slow growing habit of infectious agents and, therefore, they are often prescribed in cases when antibiotics and sulfa drugs ineffective. But a number of nitrofuran drugs have a lot of side effects.

The new drug nitrofuran series - Makmiror

Makmiror (INN - nifuratel) - a derivative of nitrofuran new generation, which produces Italian pharmaceutical company Polihim. Makmiror is highly efficient with respect to the sensitivity to the hair in combination with low toxicity and few side effects, and the almost complete absence of contraindications for use. Each tablet contains 200 mg Makmiror nifuratel, in a single package - 20 tablets.

Makmiror tablets suppress the livelihoods of many Gram-positive and Gram-negative bacteria - staphylococci, enterococci, E. coli, Salmonella, Klebsiella, chlamydia Chlamydia: insidious and widespread disease And Helicobacter pylori, which causes stomach ulcers and duodenal ulcers. Makmiror is also effective against some protozoa (intestinal amoebas, giardia, trichomonas) and fungi (yeast fungi of the genus Candida).

In some cases, prescribe Makmiror tablets

Makmiror tablets prescribed for a variety of infectious and inflammatory diseases caused by susceptible to the infectious agents. The sensitivity of the infectious agents checked by preliminary laboratory studies and only after that is assigned to treatment Makmiror.

Often Makmiror included in the complex treatment of erosive and ulcerative gastritis, gastric ulcer and duodenal ulcer caused by infection of Helicobacter pylori diseases.

Assign Makmiror and some intestinal infections, for example, intestinal amebiasis, salmonellosis Salmonellosis - features of the disease , Dysentery, and so on. It is administered as a separate antiseptic or in combination with other antibacterial drugs including antibiotics.

Effective Makmiror for various infectious and inflammatory diseases of the kidney and urinary tract - pyelonephritis, cystitis, urethritis. In acute pyelonephritis and acute exacerbation of chronic pyelonephritis it is usually prescribed as maintenance therapy after a course of antibiotics, but is sometimes used at the same time with them. In chronic pyelonephritis it is used to prevent the recurrence of the disease (anti-treatment is usually carried out in spring and autumn). When cystitis and urethritis Makmiror prescribed courses both independently and in combination with antibiotics.

Apply Makmiror well as infectious and inflammatory processes of female genital mutilation, including those caused by sexually transmitted diseases. It is effective in trihominiaze, chlamydia, candidiasis and other diseases caused by susceptible pathogens Makmiror.

Contraindications

Makmiror tablets has very few contraindications, as well tolerated. It just is contraindicated in case of hypersensitivity to it, and the body of the patient during feeding baby Breastfeeding - a personal choice   feeding.

Makmiror crosses the placental barrier. And despite the fact that there was no evidence of its negative impact on the body of a pregnant woman and the fetus during pregnancy, this drug is given only if the expected benefit to the mother's body outweighs the potential risk to the fetus. Not applicable as Makmiror negative impact on spermatogenesis and fertilization.

Minor side effects are possible - a nausea, abdominal pain Abdominal pain: Types and Symptoms Diarrhea and other discomfort from the gastrointestinal tract. Allergic reactions are also possible. But the side effects are relatively rare, generally well tolerated.

Galina Romanenko

Makmiror and Makmiror complex are drugs that suppress the livelihoods of many infectious agents. But the peculiarity of the infection today is that it does not always show sensitivity to a particular drug, so the treatment of infectious and inflammatory diseases should be like a laboratory control.

Formulations Makmiror

The Italian pharmaceutical company produces Polihim Makmiror in different dosage forms:

• Makmiror - tablets for oral use - their composition is developed a new synthetic drug manufacturer - nitrofuran derivative nifuratel which has antimicrobial, protivohlamidiynoe, antiprotozoal, antifungal activity and almost no side effects; resistance to this drug pathogens develops very slowly; one tablet contains 200 mg Makmiror nifuratel;
• Makmiror complex in the form of vaginal suppositories Vaginal suppositories - for contraception and treatment of inflammation   - It incorporates nifuratel and antifungal antibiotic Nystatin, which enhances the antifungal activity nifuratel; one candle Makmiror complex contains 500 mg nifuratel and 200,000 units of nystatin;
• Makmiror complex in the form of a vaginal cream, which also includes nifuratel and nystatin Nystatin - help with candidiasis   (1 g of cream contains 100 mg and 40,000 U nifuratel nystatin).

Makmiror Makmiror complex and are highly effective and non-toxic drugs to treat a variety of infections.

With which diseases and how to apply the tablet Makmiror

Makmiror tablets for oral administration are appointed for certain intestinal infections, as well as infectious and inflammatory diseases caused by the pathogen Helicobacter pylori. This infectious agent is the cause of erosive and ulcerative processes in the upper part of the gastrointestinal tract. In particular it causes gastric ulcer and duodenal ulcer. For the treatment of this disease Makmiror administered as part of a treatment with 400 mg (2 tablets) two or three times a day for a week; children the dose is calculated based on 30 mg per kg body weight per day.

Appointed Makmiror and certain intestinal infections (eg, in intestinal amebiasis), as well as giardiasis. These diseases are caused by protozoa, which Makmiror has sustained impact. In these diseases Makmiror designate two tablets three times a day for adults and 30 mg per kg body weight per day for children. The duration of treatment in the intestinal amebiasis - ten days, giardiasis - a week.

Often Makmiror tablets prescribed for a variety of infections of the urinary tract - as with any drug nitrofuran series it suppresses the livelihoods of the majority of these pathogens. Adults Makmiror assigned one or two tablets three times a day for children and the rate of 30-60 mg per kg body weight per day. Treatment usually lasts longer than with other diseases - for one - two weeks (as prescribed by a doctor), sometimes more durable.

Makmiror complex vaginal suppositories

Makmiror complex vaginal suppozitoorih (candlelight) is indicated for the treatment of vaginitis (inflammation of the external genitalia and the vagina of women) of different origin. A special feature of the drug Makmiror complex is that it copes with mixed infections caused by bacterial - Chlamydia - protozoal - a fungal infection. And in the case of trichomoniasis infection not only get rid of Trichomonas vulvovaginitis Vulvovaginitis - a disease of children and the elderly But also prevent the development of fungal infection that often develops on the background of such treatment.

Vaginal suppositories Makmiror complex designate suppository daily for at least eight days. On prescription treatment may be extended. Candles are introduced before bedtime Dreams: how to understand our dreams   as deeply as possible into the vagina (as efficacy of treatment above). Vaginal suppositories are usually not prescribed for children.

Makmiror complex as a vaginal cream

The dosage form of the drug can be used for treating vulvovaginitis, in both adults and children. Cream Makmiror complex is produced together with a special applicator - a dispenser to use as detailed in the instructions to the drug. The applicator is screwed into the tube of cream, by pressing on the tube it is dialed a certain dose of cream, then unscrewed from the applicator tube is placed deep in the vagina and the cream squeezed. In the applicator has a special attachment that allows you to enter the cream into the vagina children without damaging the hymen. Cream Makmiror complex is administered once or twice a day for 2, 5 g for eight days.

Makmiror Makmiror complex and are the drugs of choice in many infectious and inflammatory diseases.

Galina Romanenko