Ornidazole - it is an antibacterial drug. Take it should be in strict accordance with the instructions of the doctor, as well as safely.

Indications Ornidazole

• Anaerobic infections (for pre- and post-surgery);
• Bacterial vaginosis;
• Amoebic dysentery;
• Tropical abscess Abscess - why it is so dangerous ulcers?   liver;
• Amebiasis of liver and intestines;
• Other infections caused by protozoa such as giardiasis, trichomoniasis.

How to receive

Ornidazole in the form of pills taken after a meal with a glass of water.

The suspension is taken on an empty stomach one hour before meals or two hours after a meal.

Safety measures

Before taking ornidazole, tell your doctor if you are taking any prescription or non-prescription medicines, especially:

• Cimetidine (an antihistamine);
• Oral anticoagulant (warfarin);
• Antispasmodics (phenytoin);
• Mood stabilizers (lithium).

In addition, the doctor needs to know if you have a disorder that causes seizures, multiple sclerosis, kidney and liver. When these violations should be taken ornidazol with increased caution.

The only strict contraindication to the use of ornidazole is a hypersensitivity to the drug.

Do not drink alcohol during the course of treatment Ornidazole, and for at least three days after the last dose. Combined with Ornidazole alcohol can cause nausea, vomiting, fever and low blood pressure.

If, during the course of treatment you will have surgery, tell the surgeon that you are taking ornidazole. This medicine may increase the effect of drugs used for anesthesia.

Pregnancy and lactation

Ornidazole can be dangerous for a developing baby in the womb, and his prescribed to pregnant women only in those cases only where the potential benefits significant risks associated with taking the drug.

It is unknown how the reception Ornidazole nursing mother can affect the baby's health; lactation prescribe it only if you can not cure a disease by using safer drugs.

Side effects

Ornidazole may cause the following side effects:

• Metallic taste in the mouth;
• Diarrhea;
• Drowsiness;
• Nausea, vomiting;
• Headache;
• Sleep disorders Dreams: how to understand our dreams .

These side effects are most typical for the period of habituation of the organism to the drug; In most cases, they pass quickly.

When the following side effects of ornidazole should consult your doctor:

• Allergic reactions manifested by symptoms such as swollen lips, hives, difficulty breathing, skin peeling, blistering, and so on;
• Severe diarrhea, including - bloody diarrhea;
• Tingling and numbness in the extremities Numbness - a harmless signal or a sign of the terrible? ;
• Confusion, dizziness, Dizziness - if the ground is slipping from under his feet , The coordination of movements;
• The tremor, muscle rigidity;
• Jaundice.

Pathogens and opportunistic pathogens (disease-causing, under certain conditions) fungi cause diseases that are widespread. Vital functions of each of these pathogens fungal infection is suppressed by various drugs antifungal drugs, what exactly set after laboratory examination.

The mechanism of action mikoflyukana

Mikoflyukan (INN - fluconazole) - is an antifungal drug that produced the Indian pharmaceutical firm "Dr. Reddi`s Laboratories Ltd" in tablets and solution for intravenous drip.

Mikoflyukan is an effective antifungal drug. Its mechanism of action is to inhibit the action of enzymes of fungi, with which block the formation of biologically active substances ergosterol vital to the construction of cell membranes of fungi. Because of this fungal cells are destroyed. Actions similar in chemical composition of the human body enzymes mikoflyukan not suppress (ie, it does not violate the metabolism Metabolism: The basis of life of all living things   in humans), is different than a number of other antifungal agents (e.g., clotrimazole).

Mikoflyukan effective in candidiasis, cryptococcal meningitis, Microsporum, Trichophyton, and some other fungal infections.

When administered mikoflyukan well absorbed in the gastrointestinal tract, food intake has no effect on its absorption. The constant drug concentration in the blood is achieved at 4-5 day admission if the first shock is given (double) dose, the constant concentration in the blood is reached on the second day. The drug penetrates well into the cerebrospinal fluid. A particularly large number mikoflyukana going to the nail, where it is maintained even for six months after treatment.

Displayed mikoflyukan kidney largely intact and a small portion in the form of metabolic products (metabolites).

Indications and contraindications for use mikoflyukana

Application mikoflyukana shown:

• in severe systemic fungal infections, such as meningitis, sepsis, pneumonia, extensive skin lesions caused by fungi sensitive mikoflyukanu; including when these diseases occurred against the backdrop of a sharp decline in immunity (eg, cancer patients after radiation therapy or chemotherapy Chemotherapy - it always falls the hair? , AIDS, organ transplants);
• in generalized (afflicting many organs and systems of the human body), candidiasis, for example, with the defeat of the organs of vision, abdominal and chest cavities, kidney and urinary tract;
• mucosal candidiasis (oral cavity, pharynx, esophagus, colon, trachea, bronchi, lungs, urinary tract);
• for the prevention of fungal infections in cancer patients on chemotherapy or radiation therapy, AIDS patients, and in other cases, reduction of immunity;
• fungal infections of the skin: the feet, body, groin, nails, pityriasis versicolor;
• when deep endemic (prevalent in certain geographical areas) fungal infections (coccidioidomycosis, paracoccidioidomycosis, sporotrichosis and histoplasmosis) in patients with immune unchanged.

Treatment should be continued until complete disappearance of all signs of fungal diseases and confirmation of recovery by means of laboratory tests. Premature discontinuation of treatment leads to the resumption of the disease.

Contraindications for use mikoflyukana:

• concomitant use of certain medications (eg, terfenadine, astemizole);
• Pregnancy and breast-feeding Breastfeeding - a personal choice   breast;
• individual intolerance of components.

It is recommended to take the drug with caution in the human liver and kidneys.

Side effects that may occur while taking mikoflyukana

When receiving mikoflyukana may experience the following side effects:

• Central nervous system: headache, dizziness Dizziness - if the ground is slipping from under his feet , Jerking;
• from the gastrointestinal tract: violation of appetite, change in taste, nausea, vomiting, diarrhea, pain and bloating;
• Liver: abnormal liver function of varying severity;
• from the hematopoietic system reducing the number of white blood cells, including granulosa (decreased immunity), decreased platelet count (bleeding tendency);
• the part of the circulatory system: heart rhythm disorders (very rare);
• Allergic reactions of immediate and delayed type.

In addition, in some cases, there are side effects such as renal failure, hair loss, increased blood levels of cholesterol and lowering of potassium.

Mikoflyukan - highly efficient, but not very safe drug, so take it without a prescription is not recommended.

Galina Romanenko