Aktovegin - without fear of negative consequences - Analogs

May 24, 2009

  • Aktovegin - without fear of negative consequences
  • Mechanism of action
  • As used
  • Analogs
  • Interesting facts

 analogs aktovegina

Analogs

It is interesting to see how aktovegin on its biochemical and physiological properties related to other drugs of similar effect.

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R-Lipoic Acid

Aktovegin used to improve the transport and utilization of glucose Glucose: The energy source  Glucose: The energy source
   (it regulates the activity of the protein-glucose transporter (GLUT-1)). Lipoic acid mimics the action of insulin The principles of action of insulin - the science of saving lives  The principles of action of insulin - the science of saving lives
 By acting on the GLUT-1 and GLUT-4 10. Glut-1 is involved in the delivery of glucose to the cells of red blood cells and brain cells, and Glut-4 transports glucose into fat and muscle cells and tissue has a greater effect on blood glucose, than Glut-1.

Insulin delivers glucose to skeletal muscle myocytes, where it is used for energy generation. During exercising muscle contractions increase expression of GLUT-4, which leads to a decrease in blood glucose levels. Another important property lipoenovoy acid - its ability to enhance the antioxidant protective barriers by increasing the amount of glutathione and protect against oxidative stress How to beat stress? Create an oasis  How to beat stress? Create an oasis
   as a result of physical exertion.

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Taurine (aminoetansulfokislota)

The hypoglycemic properties of taurine (aminoetansulfokislota) significantly enhanced after administration of glucose as compared with those before the administration of glucose. Action taurine based on the stimulation of insulin secretion from the beta cells of the pancreas Diabetes and pancreas - the things you need to know  Diabetes and pancreas - the things you need to know
   and protect it from lipid peroxidation. The antioxidant properties of taurine are also valuable for the skeletal muscles: thanks to them that taurine reduces muscle damage as a result of physical activity, thereby increasing physical endurance and performance.

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Vinpocetine

Vinprotsetin obtained from the extract of periwinkle is used as nootropics (a class of drugs that enhance cognitive function, including memory, mood, vigilance) for treating cerebral ischemic disease. As aktovegin, improves cerebral blood flow vinprotsetin in patients with ischemic stroke, especially in the areas of increased concentrations of the drug. But, unlike aktovegina, vinprotsetin hardly affects deposit and glucose metabolism in the brain, therefore, can not be used for the treatment of senile dementia.

Pinched nerve - what to do when severe pain? - Symptoms

May 21, 2009

  • Pinched nerve - what to do when severe pain?
  • Symptoms
  • First aid
  • Treatment

Pinched nerve - Symptoms depend on the level of the lesion of the spine

Pinched nerve in the majority of cases associated with diseases of the spine. An exception may be the effects of trauma (proliferation of connective tissue in the area of ​​the passage of the nerve trunks), and tumors that compress the nerve. The symptoms of a pinched nerve at different their causes are similar.

 Symptoms | pinched nerve - what to do when severe pain?

Common symptoms of a pinched nerve

The roots extending from the spinal nerves contain motor, sensory and autonomic fibers. If the infringement of the spine usually develop signs of all kinds of nerve fibers. The main symptom of a pinched nerve is suddenly or gradually increasing pain - it says about the defeat of the sensory nerves.

Pain can wear shooting, cutting, piercing nature permeate the patient's body like an electric shock. Pain may occur in the form of attacks (sometimes even during sleep), or be permanent. Localized pain along the affected nerve. If a person is suffering from osteochondrosis, the bouts of severe pain may occur in the background of stress, colds, after acute diseases. If the infringement joins the inflammatory process, the skin, redness and swelling.

Infringement of motor nerve branches is accompanied by impaired contractility of the muscles below the injury that will eventually lead to a decrease in the volume of these muscles (atrophy).

If the infringement branches autonomic nerves that innervate the internal organs and blood vessel walls, changes occur in these organs. Thus, under the action of nerve entrapment occurs spasm of blood vessels, organs and tissues to which these vessels are blood loses nutrients and oxygen, this results in the gradual development of these persistent metabolic disorders Metabolism: The basis of life of all living things  Metabolism: The basis of life of all living things
 . For example, in the cardiac muscle, thus may develop miokadiodistrofiya - disease appears vague pain in the heart, heart rhythm disturbances. Changes in the respiratory and digestive organs can also lead to the development of various chronic diseases.

 Symptoms | pinched nerve - what to do when severe pain?

Signs of pinch spinal nerves extending from the cervical spine

When pinched nerves extending from the cervical spine, there is a one-sided pain in the neck. This pain often moves to the hand and may be aggravated by any movement of the neck, head or hands. Sensory disturbances manifested as numbness in the hands, tingling of the skin in the arm.

Since cervical osteochondrosis Cervical osteochondrosis - the lot of office workers  Cervical osteochondrosis - the lot of office workers
   often accompanied by sharp protective trachelism, this may lead to constriction of blood vessels that carry blood to the brain. It can cause dizziness, headaches and present danger to the life of the patient: a sharp spasm of cerebral vessels can cause the development of ischemic stroke - necrosis of the brain cells.

 Symptoms | pinched nerve - what to do when severe pain?

Signs of pinch spinal nerves extending from the thoracic spine

When pinched nerves extending from the thoracic spine, pain in the back, accompanied by persistent spasm of the muscles of the back and tilting the torso. If the infringement of the intercostal nerves, pain between the ribs, often painful, persistent or shooting, aggravated by emotional and physical exertion and awkward movements.

Infringement thoracic nerve is also often accompanied by pain and dysfunction of the organs of the chest and abdomen. Pain in the heart Pain in the heart - always consult a doctor  Pain in the heart - always consult a doctor
 , Irregular heartbeat, stomach pain, heartburn, bloating.

 Symptoms | pinched nerve - what to do when severe pain?

Signs of pinch spinal nerves extending from the lumbosacral spine

When pinched nerves extending from the lumbosacral spine, there are pain aching, breaking out of character. If it affects the autonomic nerve branches are possible violations of the pelvic organs, until incontinence.

But most of all there is infringement of the sciatic nerve Infringement of the sciatic nerve: why it happens  Infringement of the sciatic nerve: why it happens
 Which is a continuation of the nerves extending from the lumbosacral spine.

At the same time there are strong pain in the buttocks and back of the thigh is usually on one side, but there are bilateral disease sciatic nerve. At the same time the patient has a characteristic position: bending the spine forward and to the side of the patient.

The pain usually starts in the lower back and move along the sciatic nerve in the buttock area, hamstring, the outer surface of the leg and foot. Often in the leg and foot numbness and there is a feeling of "pins and needles" in the skin. The disease can lead to muscle weakness, paresis and paralysis.

Pinched nerve is one of the most frequent diseases.





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