Cerebral vasculitis usually secondary. They develop as a complication of another disease - infection, tumors, infectious and allergic process and so on. But in some cases it can develop and primary vasculitis - an isolated vascular lesions of the brain.
What is cerebral vasculitis
Cerebral vasculitis - an inflammation of the infectious nature in the walls of cerebral blood vessels. Cerebral vasculitis may be of different nature. This may be an isolated primary cerebral vasculitis, cerebral vasculitis as one of the types of lesions in systemic vasculitis secondary to cerebral vasculitis associated with systemic lupus erythematosus, systemic sclerosis
Scleroderma - affects all the organs
Rheumatoid arthritis
Rheumatoid arthritis - debunking myths about the disease
, Rheumatism, various infections and cancers.
Isolated primary cerebral vasculitis
Isolated primary cerebral vasculitis
Vasculitis - when blood vessels refuse to work
- This is a very rare and serious disease, the cause of which today are unknown. When the disease occurs isolated lesion arteries or veins of the brain of any caliber with the subsequent formation of areas of narrowing and impairment of cerebral circulation.
The disease can develop at any age, both men and women, but more often it occurs after forty years. It begins usually acute, with severe headache, seizures or convulsions appearance of focal neurological symptoms (sensory disturbances, vision, hearing, paralysis, etc.). In some cases, the disease can occur long time without any manifestations and only then to a flare with characteristic features.
The flow of the isolated cerebral vasculitis may be different. Sometimes it is accompanied by mental health problems with the formation of persistent violations of nature - psihopatizatsii. In some cases, vasculitis proceeds as multiple sclerosis with the advent of increasing fatigue. There are also cases where the primary manifestations of cerebral vasculitis can not be distinguished from a tumor compressing the surrounding tissue.
Influenced by vascular changes in brain tissue may occur numerous violations - there are areas of ischemia, necrosis, hemorrhage, and so on. The disease runs hard and is progressing steadily.
Diagnosing it is extremely difficult, since the definitive diagnosis can only be made when taking a biopsy (tissue slices of the vessel in the study). But it is usually not possible, since it is associated with a risk of bleeding.
Treatment of this disease is carried out on the basis of neurological department mainly symptomatic agents.
Cerebral lesions in systemic vasculitis
Cerebral vasculitis may complicate the course of systemic vasculitis such as periarteritis nodosa, Chardjui Strauss syndrome, Wegener's granulomatosis, a nonspecific aortoarteriit, Behcet's syndrome.
Thus, when periarteritis nodosa and Strauss syndrome Chardjuy CNS manifested in the form of violent movements (hyperkinetic) and convulsive seizures which, nevertheless, it is treatable. Wegener's granulomatosis appear blurred vision, hearing loss, drooping eyelids may also develop meningitis. When nonspecific aortoarteriit (Takayasu's disease) appear orthostatic (with a sharp transition the patient from horizontal to vertical position), fainting, headaches, worse during chewing.
In the initial stage, all these manifestations is quite treatable using hormone replacement therapy
Hormone therapy - is it possible to fool nature?
.
Secondary cerebral vasculitis
The most common secondary cerebral vasculitis develop on the background of rheumatic diseases and systemic diseases of the connective tissue (connective tissue). Thus complications of the central nervous system are not always connected with inflammatory changes in the walls of blood vessels. They often develop on the background of high blood pressure or kidney damage.
That is vasculitis in these diseases develop relatively rare, due to the presence of the blood-brain barrier to enter the brain vessels of various substances contained in the rest of the bloodstream. The properties of the inner lining of the brain vessels (endothelium), such that the transition of vasculitis in the blood vessels of the brain is often changed reactivity and the main disease is wiped out, not so aggressive. On the one hand it's good, but on the other makes it difficult to diagnose.
A manifestation of secondary cerebral vasculitis may be increasing dementia, psychosis, seizures, ischemic (with eating disorders of brain tissue) or hemorrhagic (due to rupture of the vessel wall and bleeding) strokes.
In the initial stage of secondary cerebral vasculitis respond well to treatment.
Galina Romanenko
