Neiromidin - a drug that restores the nerve impulses from neuron to neuron and muscle cells. Therefore, it is used in the treatment of various diseases of the nervous system
Diseases of the nervous system - the basic classification
Which are accompanied by impaired transmission of nerve impulses.
The mechanism of action neuromidin
Neiromidin (active substance - ipidacrine) - is an anticholinesterase drug that produces Latvian farmvtsevticheskaya company OlainFarm in tablets of 20 mg, in the form of a solution for parenteral (bypassing the gastrointestinal tract) administration in capsules of 5 and 15 mg in one ml.
Neuromidin action mechanism is that it reversibly inhibits the enzyme cholinesterase. And as cholinesterase breaks down acetylcholine, the amount of the latter increases. Acetylcholine is a neurotransmitter - a substance with which nerve impulses are transmitted from neuron to (neuron - a nerve cell) and muscle cells to neurons. As a result, it stimulated transmission of nerve impulses in the nervous system.
Under the action neuromidin increases the effect on the smooth muscle of substances such as epinephrine, serotonin, histamine and oxytocin. All of this helps to improve the condition of patients with diseases of the nervous system, improves memory, prevents the rapid development of dementia (dementia) in older patients.
If ingestion neuromidin fairly quickly enters the blood, limiting its concentration in blood is achieved within an hour after ingestion. For intramuscular or subcutaneous administration limit its concentration is reached after half an hour. Decomposed drug in the liver and excreted in the urine.
Indications and contraindications
Neiromidin appointed in the following cases:
- in various diseases of the peripheral nervous system - neuropathies (multiple lesions of peripheral nerves non-infectious), poliradikulopatiyah (lesions of the nerve roots of the spinal cord), myasthenia gravis (severe diseases of the neuromuscular system, which are characterized by rapid muscle fatigue), myasthenic syndromes developing on the background of other diseases ;
- in various diseases of the central nervous system - the effects of paralysis and paresis after stroke, traumatic brain injury, against brain tumors;
- Alzheimer's disease and senile dementia rising fast;
- In marked decrease in the motor activity of the intestine.
Application neuromidin contraindicated in case of hypersensitivity of the patient to the drug, epilepsy, ataxia, extrapyramidal disorders that are accompanied by violent movements, angina, a very slow heart rate (bradycardia), bronchospasm, gastric ulcer or duodenal ulcer in the acute stage, mechanical intestinal obstruction , bile or urinary tract infections, pregnancy (increased motor activity of muscles of the uterus), breast-
Breastfeeding - a personal choice
breast, as well as under the age of 18 years.
Be wary appoint neuromidin gastric ulcer and duodenal ulcer without exacerbation, increased thyroid function
The thyroid gland - is responsible for your hormones
, Diseases of the circulatory system, obstructive (with impaired patency of the bronchi) bronchitis. Since the tablets neuromidin includes milk sugar (lactose), they can not be given to patients with lactase deficiency (lack of lactase - an enzyme decomposing lactose), malabsorption syndrome (malabsorption of simple carbohydrates in the small intestine).
Side effects and overdose
In applying neuromidin may cause the following side effects: enhanced salivation and sweating, enhanced or, on the contrary, a rare heart rate (tachycardia or bradycardia), nausea, diarrhea, stomach pains, increased sputum in the bronchi, seizures.
If neuromidin administered in high doses, it may cause headache, dizziness
Dizziness - if the ground is slipping from under his feet
, Drowsiness, vomiting. As the dose of the drug all of these events usually take place.
Side effects may also be allergic reactions. All side effects neuromidin worse while taking alcoholic beverages. During the course of treatment is not recommended neuromidin perform work requiring the coordination of movements and concentration, including drive motor vehicles.
All side effects are amplified as the background of drug overdose. It is recommended to seek medical help.
Neiromidin - a drug that can be used only on prescription.
Galina Romanenko