Dicynonum - a drug that strengthens the walls of blood vessels, prevent exudation through their blood, stops bleeding and activates the blood flow in the right direction. Apply Dicynonum bleeding, hemorrhagic diathesis, lesions of the blood vessels in diabetes and many other diseases.

How does Dicynonum

Dicynonum (active substance - etamzilat) refers to a group of medicines - angioprotectors that improve the condition of blood vessels.

Dicynonum main action is aimed at strengthening the walls of blood vessels. Under its influence the walls of arteries, veins and capillaries are strengthened large molecules of mucopolysaccharides. This reduces the permeability of blood vessels, which is especially important for certain blood diseases, such as hemorrhagic diathesis (they are characterized by bleeding disorders).

If the damage of blood vessel walls Dicynonum stimulates clotting factor III (thromboplastin), which in turn activates the physiological mechanisms of blood clotting. Furthermore, Dicynonum promotes enhanced synthesis and platelet adhesion (sticking) at the violation of the integrity of the vascular wall.

It is assumed that Dicynonum causes increased thrombus formation. However, manufacturers still recommend not to assign Dicynonum thrombosis and thromboembolism.

Dicynonum available in tablets of 250 mg in 2 ml ampoules (one ampoule contains 250 mg etamzilata). Dicynonum acts quickly and effectively, so it is used to stop bleeding. Withdrawal of the drug largely intact through the kidneys.

In what diseases and conditions prescribed Dicynonum

Dicynonum administered at a reduced clotting disorders permeability of blood vessels and bleeding of various origin. For Dicynonum often prescribed as part of a treatment for hemorrhagic diathesis - diseases that are accompanied by increased bleeding (for example, idiopathic thrombocytopenic purpura, hemorrhagic vasculitis Hemorrhagic vasculitis - a rare disease   and so on).

Dicynonum often given immediately before and after various surgical interventions. Especially effective Dicynonum during operations on the organs and tissues that are rich in blood vessels, such as the tonsils, retina, genito-urinary organs, and so on. Dicynonum widely used in plastic surgery to reduce the rate of complications and accelerate recovery period.

In gynecological practice is used in Dicynonum prolonged and heavy menstruation intermenstrual bleeding, which can lead to iron deficiency anemia. Such bleeding is often the result of hormonal disorders Hormonal disorders - oversupply and a lack of equally dangerous , The use of intrauterine contraception and uterine fibroids.

In some diseases of the kidneys (eg, in glomerulonephritis) in the urine can be isolated blood. Dicynonum introduced in the complex treatment will help reduce such bleeding. Apply it and nosebleeds, developed on the background of high blood pressure.

When hemorrhagic stroke in adults and intracranial hemorrhages in neonates birth injury Birth injuries - than they threaten your child?   Dicynonum help stop internal bleeding and prevent the development of severe lesions of the brain.

Diabetes is often caused by lesions of the small blood vessels. Especially dangerous is the loss of blood vessels in the eye with a hemorrhage in the retina - this can lead to total blindness. To prevent this complication in patients with diabetes are used Dicynonum.

Apply Dicynonum in emergencies to reduce bleeding, occurred against a background of trauma, as well as bleeding from internal organs (eg, gastric ulcer or duodenal ulcer).

This can not be used Dicynonum and its side effects

Dicynonum can not be used when you are hypersensitive during lactation (Dicynonum application requires temporary interruption of breastfeeding, as it stands with the women's milk), thrombophlebitis, and thromboembolism, certain kinds of cancer in children, acute porphyria (congenital metabolic disorders Metabolism: The basis of life of all living things Which is accompanied by neuro-psychiatric seizures).

Side effects Dicynonum can note the appearance of headaches, dizziness, flares, disturbances of sensation in the lower extremities, nausea, heartburn, discomfort in the stomach, reducing the systolic (upper) blood pressure, allergic reactions.

Dicynonum well tolerated and rarely has side effects - a nontoxic drug.

Galina Romanenko

Pain, feeling of heaviness in the legs, cramps in the calf muscles - all these signs indicate chronic venous insufficiency Venous insufficiency - rapidly Youthful disease That is, to reduce the tone of the vein walls and malfunction of the venous valves. Such patients may help drugs based on natural - bioflavonoids.

Chronic venous insufficiency and bioflavonoids

The blood in the veins in the direction from the periphery to the heart, and if the walls of veins normal tonus, the entire it comes near to thence into the lungs, to give carbon dioxide and "charged" with oxygen. In chronic venous insufficiency decreases tone of veins, disrupted venous valves that resist backflow of blood, the blood stagnates in the lower extremities, veins dilate and the skin appear blue vein branches. All this leads to the fact that the blood becomes more viscous thrombus formed therein, there is an inflammation of the vein walls (thrombophlebitis), veins occluded by thrombus, the metabolism Improves metabolism and losing weight without dieting   in the soft tissues of the lower limb and emerge sores. At the same time gradually and steadily decreased exercise tolerance, that is, patients can not long stand and walk. Most women suffer from this disease.

Enlarge venous outflow, remove congestion in the veins, improve the tone of the vein walls may help drugs containing natural plant substances - bioflavonoids. Bioflavonoids are found in plants, many of which are the pigments that give color flowers and fruits of plants, but there are also colorless bioflavonoids. In addition to strengthening the capillary walls and bioflavonoids have anti-inflammatory effects.

Mechanism of action

The structure includes two detraleks bioflavonoid - diosmin and hesperidin. Diosmin is obtained from plants of the family Rutaceae by extraction and special chemical cleaning. The composition of one tablet Detraleks micronized flavanoidnaya included fraction consisting of diosmin (90%), and hesperidin (10%).

Diosmin improves blood circulation in the veins, strengthens and tones of the walls, helps to reduce swelling, stimulates lymph circulation. But diosmin poorly absorbed in the gastrointestinal tract, therefore the action of the preparations containing diosmin, grows slowly and depends largely on the received dosage and duration of use. To improve absorption diosmina apply different processing methods, such as ultrasound micronization.

Another component detraleks - hesperidin is produced from citrus fruit. It also strengthens and tones the walls of veins. In addition, hesperidin has antihistamine properties, that is, reduces the allergic disposition and acts as an estrogen-like substance (that is, similar to the female sex hormone estrogen). Hesperidin also has the property to protect other bioflavonoids (in this case diosmin) from the toxic effects of free radicals. The complex diosmin and hesperidin strengthen action each other and have a positive effect on blood circulation in the veins and lymph circulation of the lower extremities, reducing inflammation and reducing the fragility of vein walls.

Indications and contraindications for appointment

Indications for use detraleks are signs of chronic venous insufficiency: the severity and morning fatigue in the legs, pain or cramps in the calf muscles, particularly at night, sores on the background of varicose veins. Take detraleks Detraleks - improves the function of blood vessels   on a tablet twice a day (afternoon and evening) with food. If necessary, your doctor may prescribe a smaller or larger dose.

Another indication for detraleks is acute hemorrhoids, which are signs of severe pain, especially during a bowel movement; often accompanied by acute bleeding hemorrhoids. If signs of acute hemorrhoids detraleks appointed as follows: the first four days - 3 tablets 2 times a day; following three days - 2 tablets 2 times per day.

During the reception detraleks need to avoid prolonged sun exposure.

Detraleks contraindicated if you are hypersensitive components of the drug, and during breast Breastfeeding - a personal choice   breasts - there are no data on the allocation of detraleks with human milk.

Pregnancy is not a contraindication to the use of direct detraleks as laboratory studies in animals showed no harmful effects on the fetus detraleks. There were also no reports of adverse effects during pregnancy detraleks women. However, since clinical studies in pregnant women have not been conducted, the drug is recommended during pregnancy only if the benefits exceed the risk of pregnant women taking this drug to the fetus.

Side effects

When receiving Detraleks side effects rarely occur, however, they still can be:

• the nervous system - dizziness, headache;
• the part of the digestive system - nausea, vomiting, diarrhea;
• allergic reaction - hives, itching.

Detraleks not affect the speed of psychomotor reactions and coordination of movements, so during treatment with this drug, you can drive a car and perform other similar works.

Galina Romanenko