Any drugs which can not be combined with the use of other drugs or foods that have a similar effect. For example, during the course of treatment can not be used nimesilom alcohol, because both nimesil, and alcohol have hepatotoxic (liver-destroying cells) properties.
Hepatotoxic effects of alcohol
Hepatotoxicity have many poisons, drugs and products. Drinking among them a special place. The reason for its toxicity to liver cells is that it decomposes in the body to metabolites (metabolic products) is in the liver. At the same time most of the alcohol is decomposed into acetaldehyde, which damages the liver cells - hepatocytes. The liver cells are damaged and die off instead grows connective tissue. When thus will replace a significant portion of the hepatocyte cells of connective tissue, the reduced function of the liver. In this case speak of alcoholic cirrhosis.
Sometimes alcohol affects the liver differently. Since alcohol itself is a source of energy, fatty acids, which normally decompose in the liver followed by the release of energy, and makes it unnecessary to accumulate in the liver. This gradually leads to fatty liver - fatty liver, in which also impairs the function of the liver. Drinking alcohol or any other hepatotoxic substances can translate steatosis in hepatitis
Hepatitis - the scourge of our time
Which then also pass in the alcoholic cirrhosis.
Toxic liver changes may occur in mild, moderate and severe forms. In mild form such changes may not be noticed, which is very dangerous, as any further use of hepatotoxic substances could lead to a sharp deterioration.
At moderate pain in the right upper quadrant, jaundice of varying intensity, during examination revealed liver dysfunction. In such a case diagnosed acute toxic hepatitis
Toxic hepatitis - the impact of harmful substances on the liver
In severe the patient has severe abdominal pain
Abdominal pain: Types and Symptoms
, Vomiting with blood, his condition is getting worse by the hour due to massive necrosis (dying off) liver cells. If time does not help, the patient goes into a coma and may die.
Can I drink alcohol during treatment nimesilom
Of course, it is impossible. Simultaneous exposure to two substances hepatotoxic very dangerous, above all, unpredictable effects on the body. Much depends on the individual, including the inherited characteristics of an organism. After alcoholic cirrhosis suffer not all patients with chronic alcoholism, but no more than 15%.
Of course, nimesil has no pronounced hepatotoxicity, however, this action is, which is reflected in the instructions in the form of possible side effects - abnormal liver function and even hepatitis. At the same time such side effects are not all the patients, and in very rare cases. This also indicates that a person has a predisposition to such changes of the liver, most likely in the form of some failure or enzymatic metabolic characteristics.
Now imagine that the liver of the patient at the same time there are two factors hepatotoxic. This can lead to instant very severe liver disease - the so-called fulminant hepatitis. Since most people do not know the genetic characteristics of their metabolism
Metabolism: The basis of life of all living things
It is better not to risk and not to drink alcohol during treatment nimesilom.
Reflected whether the prohibition of alcohol in the treatment of nimesilom instructions
An outright ban on the simultaneous reception of Nimes and alcohol in the instruction no. This is surprising for such a large pharmaceutical companies such as Berlin-Chemie.
But if you carefully read the instructions, you can see that nimesil contraindicated in hepatic dysfunction and chronic alcoholism (where is the guarantee that in patients with chronic alcoholism no hidden liver damage). In addition, the side effects of the drug have a point that there were cases of fulminant hepatitis in patients receiving nimesil. How is it possible to combine the reception albeit not very strong hepatotoxic drug nimesil alcohol, which has a selective and very strong toxic effect on the liver cells?
How to take nimesil
Nimesil take one sachet of 100 mg twice daily after meals. The contents of the sachet are poured with a cup of water (about 100 mL). Divorced nimesil immediately taken, it can not be stored. The course of treatment should last no more than 15 days.
About taking alcohol during treatment nimesilom not out of the question.