Ursosan - drug in the form of solid capsules; a composition of each capsule consists of two hundred and fifty milligrams of ursodeoxycholic acid and certain excipients - including maize starch, colloidal silica, magnesium stearate.
Ursosan used to treat uncomplicated cholelithiasis and primary biliary cirrhosis, as well as for dissolution of cholesterol gallstones in conditions of normal operation of the gallbladder
Gall bladder: structure and function
. Ursosan can be taken at any age - for children under a certain age, body weight which is less than forty-seven kilograms ursosan comes in the form of a suspension.
Ursosan the treatment of cholestatic liver diseases
In the treatment of primary biliary cirrhosis, and other cholestatic liver diseases of various origin Ursosan recommended dose depends on the body weight varies from three to seven capsules per day (milligrams fourteen ursodeoxycholic acid per kilogram of body weight). During the first three months of treatment, the daily dose is recommended to be divided into several doses throughout the day. After improving liver Ursosan daily dose can be administered once a day in the evening.
- When body weight in forty-seven - sixty-two kilos daily dose Ursosan is twelve to sixteen milligrams per kilogram of body weight. During the first three months it is recommended to take one capsule three times a day, then - three capsules before going to bed at the same time.
- When body weight in sixty-three - seventy-eight kg daily dose of Ursosan thirteen - sixteen milligrams per kilogram of body weight. During the first three months is recommended to take one capsule in the morning, one - day and two - in the evening, during the subsequent treatment - four capsules before going to bed at the same time.
- When the mass of the body in seventy-nine - ninety-three kilos daily dose Ursosan of thirteen - sixteen milligrams per kilogram of body weight. During the first three months it is recommended to take one capsule in the morning Ursosan two - day and two at night, during the subsequent treatment - five capsules at a time before going to bed
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.
- When the body weight of more than ninety-four kilograms daily dose Ursosan is fourteen - sixteen milligrams per kilogram of body weight. During the first three months of treatment, you should take two capsules three times a day, during the subsequent treatment - six capsules before going to bed at the same time.
Limiting the duration of the treatment of primary biliary cirrhosis ursosan and other cholestatic liver diseases there. In rare cases, early treatment has been some worsening of symptoms - for example, intense itching. In such cases it is advisable to reduce the dose Ursosan one capsule a day, and then gradually increase the dose.
Ursosan for the dissolution of cholesterol gallstones
The recommended dose for adults - eight to twelve milligrams of ursodeoxycholic acid per kilogram of body weight in two doses per day. When dissolving gallstones recommend the following receiving mode Ursosan:
- When the body weight of fifty-sixty-two kilos - two capsules Ursosan a day (in two stages)
- When body weight in sixty-three - eighty-five kilograms - three capsules Ursosan a day (in two stages)
- When body weight in eighty-six - one hundred and twenty kilograms - four capsules Ursosan a day (in two stages)
If the dose is uneven, the highest dose should be taken in the evening Ursosan (for example, one capsule in the morning and two more - before going to bed). Depending on the size and composition of the rocks to dissolve gallstones takes six to twenty four months.
Similar dosage Ursosan by dissolving cholesterol gallstones is suitable for the elderly. In children, the formation of gallstones is very rare, but if necessary Ursosan dosage depends on the weight of the child.
How dangerous ursosan?
Ursodeoxycholic acid, the main active ingredient Ursosan, can cause diarrhea. In very rare cases, long-term treatment ursosan biliary cirrhosis and other liver diseases there is an acute pain in the abdomen
Acute abdominal pain
right. Very rare cases of calcification of gallstones as a result of receiving Ursosan and allergic reactions
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the skin (known as urticaria or hives).
In the event of an overdose of the drug may experience diarrhea. In general, other symptoms overdose ursosan very rare (almost never) since UDCA absorption decreases with increasing dose and, consequently, more substance leaves the body with stool.