Treatment of acute inflammation of the bladder

It is important to start treatment of acute inflammation of the bladder as soon as possible because if left untreated, it can develop into a kidney infection. Kidney infections - a dangerous breach requiring immediate treatment, since it is likely that they can lead to kidney damage and even death.

To combat the bacteria which cause acute cystitis Acute cystitis: Treat treated responsibly Apply antibiotics. Type of prescribed antibiotics and duration of treatment depends on what kind of bacteria caused the infection, as well as on factors such as age, sex, and general health of the patient. The most commonly used antibiotics such as amoxicillin, trimethoprim / sulfamethoxazole, fluoroquinolones, tetracycline and doxycycline.

To completely get rid of the harmful bacteria and prevent relapse, you need to take medications as recommended by your doctor and undergo treatment until the end. After the treatment the doctor may do a urine test to make sure the infection is really cured.

Some people suffer from cystitis often - more than three times a year. In such cases, the doctor may prescribe a low-dose antibiotic intake during at least six months - this helps to prevent repeated infections. Scientists are now working to develop a vaccine against acute inflammation of the bladder, which can be taken in the form of tablets or vaginal suppositories Vaginal suppositories - for contraception and treatment of inflammation .

However, people who show signs of acute inflammation of the bladder, do not always go to the doctor. The symptoms of this disorder can be alleviated at home. It is recommended to drink plenty of water, give up coffee, alcohol, and smoking. Also it can be applied to the lower abdomen warmers and take non-prescription pain relievers, which include, for example, ibuprofen or paracetamol. These drugs help reduce the pain during urination and relieve other symptoms of acute cystitis. It is important to remember that these measures will only help relieve the symptoms of acute inflammation of the bladder, but not cure it. If after a few days of home treatment you will not notice significant improvement, consult a doctor.

Preparations

Currently, no drug has been considered an ideal treatment for acute inflammation of the bladder Urinary bladder - structure and function And doctors prescribe medication, given the characteristics of each case. Choosing antibiotics, doctors are based on the available information on their effectiveness, the likelihood of side effects, and so on. It is also necessary to take into account the history of the patient, in particular to his allergy to any drugs. Typically, patients noticed relief of symptoms within 36 hours after the start of treatment.

In the treatment of acute inflammation of the bladder can be used the following antibiotics:

• Fosfomycin - three tablets per day;
• Nitrofurantoin - 100 mg twice a day for five days;
• Trimethoprim / sulfamethoxazole - 160-800 mg per day for three days;
• Ciprofloxacin - 250 mg twice daily for three days;
• Levofloxacin - 250 mg per day for three days;
• Amoxicillin / clavulanate - 500 mg twice a day, during seven days;
• Cefdinir - 300 mg twice a day for ten days;
• Tsefrodoksim - 100 mg twice a day for seven days.

Antimicrobial resistance

Beta-lactam antibiotics, which include, for example, amoxicillin and penicillin, are not recommended as first choice in the treatment of acute inflammation of the bladder, as it is now becoming more common strains of E. coli that are resistant to these types of drugs. According to some sources, already more than 20% of available resistance beta-lactam antibiotics. Fluoroquinolone resistance in Europe and North America is now less than 10%, but given the trends of recent years, in the future it could increase significantly. To preserve the effectiveness of this drug, it is also recommended to prescribe only in cases where an acute inflammation of the bladder Inflammation of the bladder - inconvenient and unpleasant   can not cure the other drugs. The effectiveness of fosfomycin and nitrofurantoin in most regions is still high. At the same time it is necessary to bear in mind that since in the course of research study, only a small part of case histories of patients with acute inflammation of the bladder, the data on antimicrobial resistance may not be very accurate.

The likelihood of antibiotic resistance rises sharply when patients are treated with antibiotics do not end up - for example, they may stop taking drugs as soon as their condition improves. This treatment approach may not only lead to a relapse, but also to ensure that the next time previously assigned to the patient an antibiotic will not help.

The mechanism of action furadonina

Furadonin (INN - nitrofurantoin) - a broad spectrum antibacterial action related to nitrofuran derivatives. Has bacteriostatic (retards multiplication of pathogens) and bactericidal (kills the pathogens) action in different urinary tract infections. Furadonin inhibits the action of bacteria such as Escherichia coli, Klebsiella, Proteus, and others. Often furadonin effective against microorganisms resistant to other antibiotics, in such cases, it is the drug of choice in their treatment.

Furadonin well absorbed in the gastro-intestinal tract, with meal increases its absorbability. In the blood, it binds to plasma proteins. Decomposes into individual metabolic products (metabolites) in the liver and muscle. Can penetrate into the cerebrospinal fluid and the placenta to the fetus, it is excreted in breast milk. Excreted by the kidneys, which are bacteriostatic and bactericidal concentrations of the drug.

Indications for use

Indications for use furadonina are infectious and inflammatory diseases of the kidney and urinary tract (ureter and bladder) caused by susceptible to the infectious agents. In recent years, it is assigned mainly composed of a complex of anti-treatment to prevent relapse of diseases of the urinary system. Appointed furadonin ordinary course of up to 10 days in some cases appointed small doses for a longer time. In order to reduce side effects while taking furadonina recommended drinking plenty of fluids, antihistamines (reducing allergic reactions) medicines and vitamins B B vitamins: the body useful helpers .

Furadonin should not be taken together with drugs that lower the acidity of gastric juice containing magnesium (reduces its antimicrobial effect), together with fluoroquinolones (eg tsiprolet).

Possible consequences

When treating furadoninom may experience the following side effects:

• from respiratory: cough, shortness of breath, chest pain, inflammatory infiltration and proliferation of connective tissue in the lungs, decreased respiratory function of the lungs, allergic diseases (asthma);
• from the gastrointestinal tract: loss of appetite, nausea and sometimes - vomiting, diarrhea, discomfort or pain in the upper abdomen;
• Liver: rare - inflammation of the liver (hepatitis), jaundice (due to the stagnation of bile in the biliary tract);
• of the central and peripheral nervous system: headache, dizziness Dizziness - if the ground is slipping from under his feet , Drowsiness, motor and sensory disorders of the peripheral nerves;
• in the blood (changes are reversible) may decrease the number of white blood cells (including granular white blood cells) in the blood (leukopenia and agranulocytosis - reduced immunity), platelet count (thrombocytopenia - a tendency to bleeding), anemia;
• Skin: various types of skin rashes;
• an allergic reaction: hives, swelling, Prevention and treatment of edema - it is important to understand the root cause   Angioedema, pruritus, rash, allergic and severe complications such as anaphylactic shock;
• Other side effects: fever, joint pain Joint pain - how to understand what is going on? , Irritation of the upper respiratory tract.

Furadonin - a drug that will still be used in diseases of the kidneys and urinary system.

Galina Romanenko