Tablets from genital herpes - the basis of antiviral therapy

May 22, 2013

 tablets from genital herpes
 To suppress the vital activity of the herpes simplex virus is assigned to antiviral therapy. Basically, anti-viral drugs are administered as tablets of genital herpes for ingestion. To this end, in the world today use acyclovir, Famvir and valotsiklovir.

 Tablets from genital herpes - the basis of antiviral therapy

Acyclovir - an antiviral drug of first generation

Acyclovir tablets - the first drug of this group. Their mechanism of action is based on the fact that getting into the tissue under the influence of acyclovir special enzymes, is converted to an active substance, which is embedded in the DNA of the virus, resulting in the formation of defective viral DNA and stopping viral replication. A feature of acyclovir tablets is that they do not affect the cells not healthy tissues. This allows you to take acyclovir for a long time without any damage to health.

Acyclovir tablets are produced by different pharmaceutical firms mainly in a dosage of 200 mg per tablet. However, some manufacturers produce atsiklorvir in other doses (400 and 800 mg per tablet).

When ingestion poorly absorbed tablets, but it was the blood of acyclovir Acyclovir - as it is safe?  Acyclovir - as it is safe?
   It has an active therapeutic effect (can penetrate into the brain tissue and penetrate into the human milk), after which decomposes in the liver to metabolites and excreted in urine.

When genital herpes acyclovir pills help prevent the spread of viral infection to the internal genitals and rapid elimination of the inflammatory process.

Acyclovir tablets should not be taken if you are hypersensitive to its components, and during lactation. They are usually well tolerated, but sometimes after their admission may appear side effects: nausea, vomiting, diarrhea, abdominal pain Abdominal pain: Types and Symptoms  Abdominal pain: Types and Symptoms
 , Allergic skin rash, headache, dizziness, sleepiness, failure of performance, concentration and mental, balding, short of the liver and kidney, changes in the blood (reduction of blood leukocytes and erythrocytes). Overdosing acyclovir leads to enhancement of its side effects.

 Tablets from genital herpes - the basis of antiviral therapy

Modern antiviral drug valacyclovir

Valacyclovir (Valtrex) is an antiviral agent of the second generation and produced it in tablets of 556 mg. Tablets of valaciclovir is converted by enzymes first into the neutral acyclovir, and then from neutral into active acyclovir acyclovir, which has antiviral activity. In this initial stage of the transformation of the inactive to the active acyclovir is influenced by enzymes secreted by the virus. This determines the specificity of valaciclovir - it acts only on specific viruses, such as herpes simplex virus types I and II, which causes genital herpes.

Valotsiklovir used as a treatment, and for the suppressive (suppressive) treatment of genital herpes. Thus, the sooner after the start of relapse assigned valacyclovir, the higher the therapeutic effect.

Valacyclovir is contraindicated in case of hypersensitivity of the patient to its components, while feeding the baby Breastfeeding - a personal choice  Breastfeeding - a personal choice
   chest and for children under 12 years. If abnormal liver function or kidney disease, severe course of AIDS valacyclovir administered with caution and at a lower, individually selected dosage.

When receiving the tablets of valaciclovir can appear side effects such as nausea, vomiting, diarrhea, abdominal discomfort, transient liver function abnormalities, headache, dizziness, mental confusion, hallucinations, impaired memory, agitation, trembling of the hands, legs and body, gait disturbance, pronunciation of sounds and words, convulsions. Most often side effects occur in patients with impaired renal function. Possible overdose valaciclovir.

 Tablets from genital herpes - the basis of antiviral therapy

The antiviral drug famciclovir last generation

Famciclovir (Famvir) is available in tablets of different dosages. Its mechanism of action is similar to the effect of aciclovir and valaciclovir, but differs in the fact that getting into the virus-infected cells, it is under the action of viral enzymes is rapidly converted into more active substance penciclovir triphosphate. The latter is a virus-infected cells to 12 hours to suppress virus replication. The concentration of penciclovir triphosphate in healthy tissue cells is less than the minimum, so the recommended doses of famciclovir tablets do not adversely affect healthy cells. Famciclovir is active against herpes simplex virus Herpes simplex - in fact, not so simple  Herpes simplex - in fact, not so simple
 Resistant to acyclovir.

Famciclovir is contraindicated only if you are hypersensitive to its components, pregnant and breast-feeding. With care it is prescribed for disorders of the liver, kidneys and childhood.

All tablets antiviral effect may appoint a doctor.

Galina Romanenko

Article Tags:
  • Treatment of genital herpes

Chronic genital herpes - recurrent

May 22, 2013

 Chronic genital herpes
 Chronic genital herpes can occur with frequent or occasional relapses - it all depends on human immunity. Often recurrent genital herpes said that the body's defenses are reduced. This requires a comprehensive examination of the patient and identify the causes of the weakening of the body.

 Chronic genital herpes - recurrent

Why chronic genital herpes is called relapsing

Chronic genital herpes is caused by types I and II herpes simplex virus Herpes simplex - in fact, not so simple  Herpes simplex - in fact, not so simple
   (HSV). Basically this HSV-II, but in some cases of genital herpes is caused by HSV-I and. Once introduced into the body, HPV stays there forever. If a person is healthy and his immune system is able to protect him from infection, HPV is hiding in the nerve ganglia, which are located in the lumbar region.

At the first episode reduction of immunity (compared to a cold, trauma, surgery, influenza, etc.) HPV in nerve trunks moved on mucosal surfaces genital skin and organs is introduced into the surface cells, it penetrates into the cell nucleus and there "churns" new viruses . Freshly virus out of the affected cells and introduced into a healthy, repeating the same cycle. When the virus becomes sufficient to begin the inflammatory process, the surface of genital herpes signs appear Symptoms of herpes - sometimes you can not even notice  Symptoms of herpes - sometimes you can not even notice

Due to the clear communication of exacerbations (relapses) of the disease to the state of immunity Immunity - types and characteristics in children in adults  Immunity - types and characteristics in children in adults
   This form of genital herpes is called recurrent.

 Chronic genital herpes - recurrent

The course of recurrent genital herpes

After HSV introduced into the body and causes the primary infection, his symptoms disappear. The further course of the disease depends on many internal and external causes (predisposing factors) that can weaken the body's defenses.

The disease can be divided into mild, moderate and severe. In less severe genital herpes recurrences occur it is relatively rare and do not last long. Typically, in this form of genital herpes is not more than four relapses per year. At current average severity of relapses develop up to six times a year, or every two months, with a heavy - monthly. For example, on a monthly basis may recur so-called "menstrual" herpes, this is due to the fact that during menstruation a woman is always slightly reduced immunity.

By types of genital herpes flow divided by arrhythmic, monotonous and subsides. When arrhythmia during relapses occur through indefinite periods of time. At the same time, the longer the remission lasted, the longer and more intense is worsening.

With monotonous during remission and relapse alternate with each other through a certain, almost always the same intervals. For example, the "menstrual" Herpes is characterized by monthly eruptions during menstruation. When subsides type of genital herpes remission gradually increased, and the duration and intensity of relapse decreases. Perhaps subsided and complete the process.

 Chronic genital herpes - recurrent

The main symptoms

Recurrences of genital herpes are different from primary herpes that they are less intensity and duration. Relapse usually begins with discomfort in the genital area, then there are few restrictions edema Prevention and treatment of edema - it is important to understand the root cause  Prevention and treatment of edema - it is important to understand the root cause
 , Rash and redness characteristic bubbles with clear content, usually grouped in one location. Bubbles burst on day 2-3, the resulting erosion heal no later than a week.

But these are typical signs of the disease does not always occur. Sometimes chronic genital herpes are asymptomatic, that is, there are no symptoms of the disease, but the infection to her sexual partner a man could pass. This dangerous form - the patient, without knowing it, is a source of infection.

There is also the atypical form of genital herpes, which manifest themselves in different ways, but symptoms usually do not look like the classic cold sores. For example, atypical genital herpes can manifest itself in the form of characteristic blisters on the buttocks.

There are rashes on the genitals, it is not like herpes, - in the form of red spots, cracks in the anus, cystitis, accompanied by pain when urinating and so on. This type of virus is very difficult to detect as patients can be treated at the years of specialists (urologist, proctologist) without any success. Gynecologists and urologists are aware that if the patient complains of long flowing incomprehensible infection that can not be cured, it is necessary to look for herpes.

Chronic genital herpes may proceed differently.

Galina Romanenko

Article Tags:
  • genital herpes