To suppress the vital activity of the herpes simplex virus is assigned to antiviral therapy. Basically, anti-viral drugs are administered as tablets of genital herpes for ingestion. To this end, in the world today use acyclovir, Famvir and valotsiklovir.
Acyclovir - an antiviral drug of first generation
Acyclovir tablets - the first drug of this group. Their mechanism of action is based on the fact that getting into the tissue under the influence of acyclovir special enzymes, is converted to an active substance, which is embedded in the DNA of the virus, resulting in the formation of defective viral DNA and stopping viral replication. A feature of acyclovir tablets is that they do not affect the cells not healthy tissues. This allows you to take acyclovir for a long time without any damage to health.
Acyclovir tablets are produced by different pharmaceutical firms mainly in a dosage of 200 mg per tablet. However, some manufacturers produce atsiklorvir in other doses (400 and 800 mg per tablet).
When ingestion poorly absorbed tablets, but it was the blood of acyclovir
Acyclovir - as it is safe?
It has an active therapeutic effect (can penetrate into the brain tissue and penetrate into the human milk), after which decomposes in the liver to metabolites and excreted in urine.
When genital herpes acyclovir pills help prevent the spread of viral infection to the internal genitals and rapid elimination of the inflammatory process.
Acyclovir tablets should not be taken if you are hypersensitive to its components, and during lactation. They are usually well tolerated, but sometimes after their admission may appear side effects: nausea, vomiting, diarrhea, abdominal pain
Abdominal pain: Types and Symptoms
, Allergic skin rash, headache, dizziness, sleepiness, failure of performance, concentration and mental, balding, short of the liver and kidney, changes in the blood (reduction of blood leukocytes and erythrocytes). Overdosing acyclovir leads to enhancement of its side effects.
Modern antiviral drug valacyclovir
Valacyclovir (Valtrex) is an antiviral agent of the second generation and produced it in tablets of 556 mg. Tablets of valaciclovir is converted by enzymes first into the neutral acyclovir, and then from neutral into active acyclovir acyclovir, which has antiviral activity. In this initial stage of the transformation of the inactive to the active acyclovir is influenced by enzymes secreted by the virus. This determines the specificity of valaciclovir - it acts only on specific viruses, such as herpes simplex virus types I and II, which causes genital herpes.
Valotsiklovir used as a treatment, and for the suppressive (suppressive) treatment of genital herpes. Thus, the sooner after the start of relapse assigned valacyclovir, the higher the therapeutic effect.
Valacyclovir is contraindicated in case of hypersensitivity of the patient to its components, while feeding the baby
Breastfeeding - a personal choice
chest and for children under 12 years. If abnormal liver function or kidney disease, severe course of AIDS valacyclovir administered with caution and at a lower, individually selected dosage.
When receiving the tablets of valaciclovir can appear side effects such as nausea, vomiting, diarrhea, abdominal discomfort, transient liver function abnormalities, headache, dizziness, mental confusion, hallucinations, impaired memory, agitation, trembling of the hands, legs and body, gait disturbance, pronunciation of sounds and words, convulsions. Most often side effects occur in patients with impaired renal function. Possible overdose valaciclovir.
The antiviral drug famciclovir last generation
Famciclovir (Famvir) is available in tablets of different dosages. Its mechanism of action is similar to the effect of aciclovir and valaciclovir, but differs in the fact that getting into the virus-infected cells, it is under the action of viral enzymes is rapidly converted into more active substance penciclovir triphosphate. The latter is a virus-infected cells to 12 hours to suppress virus replication. The concentration of penciclovir triphosphate in healthy tissue cells is less than the minimum, so the recommended doses of famciclovir tablets do not adversely affect healthy cells. Famciclovir is active against herpes simplex virus
Herpes simplex - in fact, not so simple
Resistant to acyclovir.
Famciclovir is contraindicated only if you are hypersensitive to its components, pregnant and breast-feeding. With care it is prescribed for disorders of the liver, kidneys and childhood.
All tablets antiviral effect may appoint a doctor.
- Treatment of genital herpes