Herpes Type 8 - is an infection that is associated with Kaposi
Sarcoma - a full recovery possible
Sarcoma. That is, the presence in the body of the infection is a predisposing factor for the development of Kaposi's sarcoma, but only if the patient suffers from immunodeficiency. In people with normal immunity
Immunity - types and characteristics in children in adults
HHV-8 causes Kaposi's sarcoma.
The herpes virus type 8
HHV-8 was opened in 1994 in the United States during the study of HIV infection among homosexual men. HHV-8 is associated with Kaposi's sarcoma, that is a risk factor for Kaposi's sarcoma, when a person is infected with HIV and suffering from immunosuppression or immune deficiency developed against the background of long-term treatment, lowers immunity (eg, cancer patients). In healthy people, herpes type 8 causes Kaposi's sarcoma.
The virus has a special gene that disrupts the synthesis of cell proteins, opposing the formation of cancer cells, therefore, contributes to Kaposi's sarcoma - a malignant tumor
Malignant tumor: cells are mad
vessels. HHV-8 is divided into three variants A, B and C - they differ in different DNA structure and cause different forms of Kaposi's sarcoma.
How is infection with herpes virus type 8
HHV-8 is not distributed as widely as other types of pathogens of herpes infection. Furthermore it is common in tropical countries, especially in Africa.
The main route of transmission of the infection - sexual, since viruses are abundantly present in the mucous membranes of the genitals. But pathogens are also present in the saliva of infected people, so dangerous kisses and too close contact.
It is also possible transmission of infection through blood, most often this happens when you use a syringe for injection into a vein of drugs to different people. Finally, it is possible (though rare) transmission from mother to child during pregnancy.
How does Kaposi's sarcoma
Kaposi's sarcoma - a multifocal malignant tumor of vascular origin. The disease develops most often in gay men and affects the skin, lymph nodes and internal organs. There are four forms of Kaposi's sarcoma: classic, African, immuno-suppressive and AIDS-related.
Variant A herpes virus type 8 is usually associated with the classical and AIDS-associated Kaposi's sarcoma shape, and with lesions of the skin and internal organs. Options B and C are associated with lymphoproliferative diseases - lymphoma, generalized lymphadenopathy, Castleman's disease.
The classical form of Kaposi Kaproshi developing long, for years. In the feet, the side surfaces of the lower leg, on the skin of the hands, sometimes - on the mucous membranes and eyelids. Characteristically symmetrical arrangement and clear lines of foci of infection, in which often develops burning and itching of the skin. In the course of the disease there are three phases:
- Spotted phase - the earliest; spots on the skin no more than 5 mm in a dark color;
- papular phase - become elements of rash papular character, spherical, dense elastic consistency and the size of up to 1 cm in diameter; sometimes they merge, forming a smooth or slightly rough plaques;
- Tumor phase - forming one or more nodes bluish red color with a diameter of 5 mm; node soft to the touch and merge with each other and ulcerate.
In AIDS patients suffering from immunodeficiency and infection with the human herpes virus infection such as Kaposi's sarcoma 8 runs hard. Get sick more often young men. The first sign of the disease is the appearance of the mouth and rashes on the sky bubble deep red color, containing clotted blood. Then the affected skin of the upper half of the body, hands and face. Sometimes, characteristic changes appear on the genitals. Patients thus drastically lose weight, become lethargic, irritable, sleep poorly. Then, increase the lymph nodes, the body temperature rises. The process involves the lymph nodes and internal organs.
The African form of Kaposi's sarcoma affects children, mostly Africans. Mainly affects lymph nodes
Lymph nodes - what keeps our immune system
and internal organs.
Immuno-suppressive form of disease develops after kidney transplantation and held in front of this immunosuppression. It is prolonged and benign.
Diagnosis and treatment of herpes virus infections such as 8
To diagnose the disease are methods of PCR (DNA detected pathogen), IFA (detected antibodies to viruses).
Treatment of Herpes type 8 - is, primarily, the treatment of underlying disease (e.g., AIDS), it leads to a resorption of Kaposi's sarcoma. They are also used drugs that restore the immune system, chemotherapy and radiation therapy.