The drug Tamiflu was set against the backdrop of increased incidence of swine flu
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for its treatment. And indeed, it was proven that Tamiflu cope with this task, suppresses reproduction, distribution of organs and tissues and excretion from the body of the patient into the environment of swine influenza viruses.
What is swine flu
It called swine influenza type A subtype H1N1. This swine disease outbreaks that occur in these animals often enough. Sometimes, the virus is transmitted to humans, but is very rare. Pigs can also get sick and pass the person (limited) and other influenza viruses such as the bird.
But a few years ago, a new swine flu virus (a combination of the genes of viruses of human, avian and swine flu), which is rapidly transmitted from person to person. This rapid spread of swine flu is because earlier this pathogen infection does not circulate, immunity
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to him the population there. The illness is usually difficult, complicated by viral infection of the lungs and has a high mortality rate.
Symptoms of swine flu are little different from symptoms of seasonal influenza type A. It is high fever, cough, nasal congestion and runny nose, sore throat, headache, muscle and joint pain, malaise. Sometimes there are nausea, vomiting and diarrhea.
But unlike the seasonal flu, swine flu may be at a very fast start, spread and very difficult to proceed complications of the respiratory tract. Pneumonia, which in this case arise, destroy lung tissue and cause the death of patients.
Symptoms of swine flu complications are the appearance of shortness of breath, difficulty breathing, cyanosis of the skin, expectoration with blood, chest pain, agitation, high fever for more than three days, reduction in blood pressure
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and severe weakness.
How to cope with swine flu
Not always the swine flu runs hard, there are cases of mild and moderate severity that is treated symptomatically, as the common flu: bed rest, drink plenty of warm, high temperature - antipyretics.
But given the possible severe complications of swine flu have been developed effective antiviral drugs to treat it - oseltamivir (Tamiflu) and zanamivir (Relenza). These drugs are able to inhibit the reproduction, distribution and excretion into the environment from the body of the patient virus.
Assign these drugs, and only a doctor if influenza is really hard.
The mechanism of action of Tamiflu when swine flu
The active ingredient of Tamiflu - Oseltamivir phosphate is initially inactive, it is absorbed into the bloodstream to the liver and under the influence of hepatic enzymes decompose there for metabolites (products of metabolism). One metabolite oseltamivir carboxylate is an active substance that suppresses reproduction and distribution of influenza virus type A (H1N1). It was found that Tamiflu is also effective against all influenza viruses types A and B.
The mechanism of action of Tamiflu due to the fact that the drug inhibits the action of influenza virus neuraminidase enzymes, without which the proliferation and spread of the virus.
Reducing the amount of infectious agents in blood and tissues reduces toxicity, easier course of disease and the risk of complications (both viral and bacterial) in the lungs.
Contraindications for receiving Tamiflu during the swine flu and its possible side effects
In severe swine flu contraindications for the use of this drug is almost there. This idiosyncrasy of its components, and severe renal dysfunction. WHO (World Health Organization) recommends prescribe Tamiflu swine flu even if children under one year, pregnant women and nursing mothers.
But this does not mean that the drug should be appointed with milder forms of swine flu or seasonal influenza A and B. Tamiflu has a lot of side effects, which can be "close their eyes" only for health reasons.
Side effects are often encountered nausea, vomiting, diarrhea, headache, irritability, fatigue, insomnia. Occasionally there are side effects such as gastrointestinal bleeding and liver dysfunction.
On the part of the central nervous system may cause severe side effects such as convulsions, confusion and even psychosis.
These flu-like symptoms, such as cough, runny nose, sore throat, inflammation of the upper respiratory tract and bronchi may increase the side effects of Tamiflu
Tamiflu - an antiviral drug for the treatment and prevention of influenza
Tamiflu - an effective tool for the treatment of severe swine flu. It used this drug on prescription.