Various pharmaceutical companies produce several analogues of the drug Meridia. The main active ingredient in all of these drugs are sibutramine - a drug that suppresses hunger by affecting the brain.
Sibutramine and its analogues
Sibutramine - a drug for the treatment of obesity of the central action. It prevents the spread of nerve impulses by inhibiting the process of recapturing some of the neurotransmitters - substances through which nerve impulses are transmitted. Simultaneously sibutramine increases energy consumption by inhibiting the reflex slowing metabolism
Metabolism: The basis of life of all living things
against falling weight. Improved by the action of this drug is also fat and carbohydrate metabolism.
Sibutramine is manufactured by different pharmaceutical companies under the following brand names:
- Meridia
Meridia - gives a sense of satiety
(Abbott GmbH, Germany);
- lindaksa (Zentiva, Czech Republic);
- Goldline (Laboratory of Ranbaxy, India);
- Slim (Torrent Pharmaceuticals Ltd., India);
- Reduxine (OOO Avista, Russia).
These drugs are recommended for use only when all other treatments for obesity have no effect. This treatment should be comprehensive and take place under the supervision of a physician, an endocrinologist with practical experience in the treatment of obesity. The complex treatment includes diet, increasing physical activity, changing the whole way of life. All this contributes to the formation of persistent changes in eating habits and lifestyle, which are needed to preserve the achieved body weight after the abolition of drugs.
The original and reproduced drugs
Any drug is available for the first time some of the pharmaceutical company that conducts all the necessary laboratory and clinical trials, drug records under some international non-proprietary name (INN), and obtained a patent for its manufacture a certain number of years. The firm gives to the drug trade (under brand) name and selling it. Such a preparation is called the original or brand. Until the patent has expired, no other firm to produce the same drug may not, but after the expiration of this period other firms can use this formula and to produce similar drugs. They all have the same INN and various trade names, manufactured by invented. These drugs are called generics.
Are there any differences between brands and generics? It would seem that there should not be, but experience shows that there are often significant. Brands usually produce big pharmaceutical company with a good reputation, which has great significance for them. Therefore, they use high quality raw material, have equipment that meets international requirements (system GMP) and comply with all technology.
Generics also produce smaller firms that do not always hold all the necessary requirements. Although, of course, and generics can be as good as brands - all individually. In the production of generics firms often save on the raw material and buy it in Asian countries, where a lack of quality control over their production. The instructions to these drugs, of course, does not reflect all the nuances, so it is difficult to directly determine the quality is generic or not.
Brands and generic sibutramine
The original drug or brand in this case is the drug Meridia, which produces the German pharmaceutical company Abbott GmbH. This drug has successfully passed all clinical trials where it has been proven safe. Meridia is done on their own original technology Abbott in accordance with international quality standards GMP. The starting material (raw materials) for the manufacture of the drug (sibutramine hydrochloride) used only the highest purity and European production.
Therefore, it is meridia quality standard for all other preparations in which the active ingredient is sibutramine
Sibutramine - effective but not safe
. All generic drugs sibutramine, which are present in the Russian market, fully replicate the original drug Meridia. Lindaksa, Goldline, Sliema and Reduxine also available in capsules, at the same dosage. Instructions to these drugs completely copied instructions in Merida.
Different prices for all of these drugs. Thus, the average price of Meridia, depending on the dosage and number of tablets in a package of 2, 5 to 4 thousand rubles and more. Lindaksa (15 mg, 90 pieces) - 5000 rubles Reduxine (15 mg 30 pieces) - 1300 rubles, Goldline - (15 mg 30 pieces) - about 950 rubles.
Which of these medicines to choose the best tell a doctor who has experience in the destination of such products.
Galina Romanenko
