- Claritin - histamine receptor blocker
- The role of histamine in allergy development
The active ingredient of Claritin is loratadine
Loratadine - a long-acting antihistamine
, A variety of drugs, which are non-sedating antihistamines are called. Histamine - a natural substance that is produced when the body is protected from hazardous substances penetrating from the outside; as well as the materials that it takes the danger. When stimuli are absent, it is simply stored in mast cells of virtually all tissues of the body.
Mechanism of allergy
When the body reacts to any foreign and potentially hazardous substances (known as allergens; these include, for example, pollen), there is stimulation of mast cells, causing them to release histamine.
The released histamine binds to histamine receptors (H1-receptors), which gives the start chain reactions that result in symptoms of allergy
Allergy symptoms: Survival Guide Spring
. As a result, it increases blood flow to the areas affected by allergies, and other chemical compounds are released, which is also part of the body's response to the contact allergen.
For example, in hay fever, histamine causes inflammation of the nasal mucosa, eyes, skin or respiratory tract, and the patient has symptoms such as itching, allergic rhinitis, sneezing, and nasal congestion.
How does Claritin
Claritin is blocking histamine receptors. Mast cells release histamine is still, however, the active ingredient Claritin does not allow him to contact the histamine receptors. Due to this, in turn, prevents the development of other chemical compounds zuchastvuyuschih in allergic reactions. As a result of the decreased due to this action of the drug in blood flow occurs relief of typical symptoms of hay fever.
Claritin is used to treat symptoms of hay fever (seasonal allergic rhinitis) in adults and children older than two years; if caused by an allergy inflammation of the nasal passages, or perennial allergic rhinitis
Rhinitis: a runny nose - is quite serious
and chronic itchy rash of unknown origin (chronic idiopathic urticaria).
Despite the fact that the non-sedating antihistamines Claritin relates, in rare cases, it can have a sedative effect. Therefore, refrain from driving and the types of work that require attention, and pose a risk to the safety of other people until you are sure that Claritin does not cause you drowsiness, dizziness, lethargy, general lethargy.
At the reception Claritin is strongly recommended to give up alcohol or significantly reduce its use.
Contraindications and side effects
Normally relief of allergy symptoms occurs within 1-3 after starting the Claritin. If symptoms persist or even weaken in a week, you need to see a doctor, as is likely, this medicine does not suit you.
Claritin should not be used for children up to two years, for children aged between two and twelve years, the body weight which is less than thirty kilograms, pregnant and lactating women, and people with congenital galactose intolerance. In some cases, when it is really necessary and safe alternatives are not available, Claritin appointed pregnant, but the reception is held under the close supervision of a physician. In most cases, this does not entail any consequences for both mother and fetus, but the safety of Claritin during pregnancy is still considered unproven.
Allergy to any components of Claritin as a contraindication to its use.
Side effects from Claritin are relatively rare. Some patients taking this medicine, complain of headaches, severe nervousness, fatigue, increase in appetite, sleep disturbances
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(usually insomnia, but there are constant sleepiness).