Panangin best made by a physician, who will determine the dosage and duration of taking this drug. Admission panangina tablets rarely leads to an overdose of its components, it is more likely to occur when administered intravenously.
How does Pananginum
The composition includes panangina potassium and magnesium salts, which improve the metabolic processes in cells of the myocardium (heart muscle). This occurs due to the fact that potassium and magnesium are part of enzymes involved in various biochemical processes. But the main purpose of the potassium and magnesium ions - maintaining a normal water-salt exchange in cells.
Panangin prescribed as part of a treatment for coronary heart disease (angina, myocardial infarction), heart failure
Heart failure - when the heart is unable to cope with the work
(including the appointment of drugs called cardiac glycosides, to reduce their toxicity), cardiac arrhythmias, with a deficiency in the body of potassium and magnesium (this condition leads to violations of the heart muscle).
How to take
Panangin made Hungarian pharmaceutical company Gedeon Richter in oral pills and capsules. Each dragee panangina contained 158 mg of potassium aspartate, magnesium aspartate 140 mg. Panangina solution for intravenous injection is available in ampoules of 10 ml. Each ml of solution contains potassium aspartate 45, 2.
Panangin in pills prescribed for one to two tablets three times a day after meals, as acidic contents of the stomach can destroy the membrane pellet. Duration of panangina determined by a physician, but on average it takes about a month. Repeated courses of treatment must also be assigned a doctor.
Intravenous drip panangina held. Drip solution prepared by dissolving the contents of one or two vials (10 - 20 mL) in 100 mL of 5% glucose solution
Glucose: The energy source
. Droppers are doing a speed of no more than 25 drops per minute one - two times a day, course of treatment - five days. You can enter and Pananginum jet, spreading all the same 5% glucose solution. But the administration has to be very slow, with the rate of 5 ml per minute.
Pananginum has a number of side effects associated with overdoses of potassium and magnesium. If ingestion severe hyperkalemia and hypermagnesemia usually does not happen, however, can develop the following side effects:
- of the central and peripheral nervous system - the sensory disturbances (numbness, formication of the body) due to high content of calcium in the blood, reducing neuromuscular reflexes, convulsions induced higher blood magnesium;
- on the part of the cardiovascular system - a violation of the conduction of electrical impulses from the atria to the ventricles of the heart (atrioventricular block), an increase in the number of premature beats (paradoxical reaction) caused by the high content of potassium in the blood, a sharp drop in blood pressure
Blood pressure - dangerous if his swing?
, Redness of the skin, feeling of heat caused by the high content of magnesium in the blood;
- from the gastrointestinal tract - nausea, vomiting, diarrhea, discomfort or pain in the pancreas region (gastritis in patients with reduced gastric acid secretion, or inflammation of the gall bladder);
- by the respiratory system - respiratory depression caused by elevated blood levels of magnesium.
But it is much more dangerous than the side effects that may occur against the background of intravenous panangina. This may develop signs of hyperkalemia and hypermagnesemia.
Simtomy hyperkalemia and hypermagnesemia
Hyperkalemia - is to increase the concentration of potassium in the blood serum, which is accompanied by severe violations of water-salt metabolism in the cells and the acid-base balance. Hyperkalemia is clinically manifested as a characteristic of the syndrome, the severity of which depends on the concentration of potassium in the blood.
A typical manifestation of hyperkalemia is a rapid increase in drowsiness and confusion, pain in the muscles of the limbs, in the language. After a while there paralysis and paresis as the skeletal and smooth muscles of internal organs. It lowers blood pressure, heart rate becoming rare, may develop heart block (disorders of conduction of electrical impulses in the myocardium), and cardiac arrest.
Increasing the concentration of magnesium in the blood (gipermagniemiya) is soothing, sometimes narcotic effect may result in respiratory arrest
Stop breathing (apnea) during sleep - upper airway obstruction
. It lowers the tone of the skeletal muscles due to violation of the mechanism of neuromuscular transmission.
Panangin not a harmless drug, it is better to take a strictly prescribed by a doctor.