Cardiomagnyl - a drug which includes the first nonsteroidal anti-inflammatory drugs (NSAIDs) - aspirin. Aspirin has many contraindications, as is able to exert significant side effects. Therefore, even in order to prevent it you need to take after the test.

Features action cardiomagnyl

Side effects and contraindications cardiomagnyl for its reception characteristics derive from its actions. As NSAID aspirin has anti-inflammatory, analgesic and antipyretic activity. In addition, it reduces the ability of blood platelets to stick together, i.e. prevents the formation of thrombi.

Some prostaglandins are active participants in the inflammatory process, other prostaglandins also protect the stomach lining from external influences. Under the effect of aspirin decreases the synthesis of prostaglandins, including those that protect the gastric mucosa - this is what provides the main side effects of the drug. In addition, by inhibiting COX blocked synthesis of thromboxane A2 - it helps reduce the aggregation (agglutination) of platelets.

The structure other than aspirin cardiomagnyl includes magnesium hydroxide, whose mission - to protect the stomach lining from the effects of aspirin.

Contraindications of the gastrointestinal tract

Despite the fact that the magnesium hydroxide is largely flattens adverse effect of aspirin on the mucosa of the gastrointestinal tract, it completely this side effect is not eliminated.

As a side effect cardiomagnyl is irritating to the mucous membranes of the gastrointestinal tract, it is not suitable for receiving any erosive and ulcerative processes in this field in the acute stage. That is, chronic erosive gastritis, gastric ulcer and duodenal ulcer gastritis, as well as bleeding from the stomach and intestines.

The caution should be applied cardiomagnil even if erosive and ulcerative processes or bleeding from the gastrointestinal tract of the patient are in the past, and then the disease for a long time in a state of stable remission.

Contraindications for increased bleeding

Cardiomagnyl inhibits platelet aggregation and thereby reduce the clotting ability of blood. Therefore, before prescribing this drug it is very important to be sure that the patient does not reduce these figures and there is no tendency to bleed. Causes of increased bleeding may be different, but in any case take cardiomagnil such patients can not.

If such patients will be assigned cardiomagnil, then they will increase the tendency to bleed, including an internal, for example, with the development of ulcer process in the gastrointestinal tract.

Contraindications cardiomagnyl the part of the brain

Cardiomagnyl is a means to prevent the development of ischemic stroke, which can occur when a sharp narrowing or thrombosis Thrombosis - the cause of heart attack and stroke   blood vessels of the brain. But in hemorrhagic stroke Stroke - a serious brain injury   cardiomagnil contraindicated, since this type of stroke develops when a blood vessel rupture and penetration of blood into the brain tissue. When blood clotting is reduced, the bleeding will be more extensive, so in this case the patient is prescribed styptic.

Contraindications for allergic diseases

Many of the NSAIDs cause or exacerbate allergic reactions, however their use is not desirable in all allergic disorders. Very often in response to aspirin bronchospasm occur. This phenomenon even has been called "aspirin" asthma. Contraindications cardiomagnil when allergic rhinitis, atopic dermatitis and other allergic diseases.

Contraindications for kidney and liver

In severe kidney disease with severe renal insufficiency Kidney failure - when treatment is vital   cardiomagnil appoint not recommended, since the decrease in renal function is disrupted the process of removing from the body of aspirin.

If kidney function is significantly impaired, the cardiomagnil used with caution. By reducing liver function will also need to be careful when taking cardiomagnyl.

Other contraindications for receiving cardiomagnyl

Cardiomagnyl should not be prescribed during pregnancy (aspirin can cause congenital malformations), while feeding the baby Breastfeeding - a personal choice   feeding, at the age of 18 and are hypersensitive to its components.

Furthermore, it can not be used concurrently with methotrexate - a drug that inhibits the action of folic acid and thus prevents the growth of malignant tumors. This drug has similar side effects as cardiomagnil.

Cardiomagnyl - this is a good preventative tool, but not quite safe, so it should be prescribed by a doctor.

Galina Romanenko

Cardiomagnyl - combined preparation, which consists of drugs that prevent the formation of clots in blood vessels. Thrombus formation is dangerous because it can lead to malnutrition of tissues, this is the cause of serious diseases such as myocardial infarction and ischemic stroke.

How does cardiomagnil

Cardiomagnyl - a drug, which includes acetylsalicylic acid (aspirin) and magnesium hydroxide. He produced tablets of different dosages (75 mg acetylsalicylic acid +15, 2 mg of magnesium hydroxide, and 150 mg of acetylsalicylic acid by 30, 39 mg of magnesium hydroxide per tablet), the Norwegian pharmaceutical company Nycomed.

The main active ingredient in the drug is aspirin. This is a drug that belongs to a group of non-steroidal anti-inflammatory drugs (NSAIDs) and has analgesic, anti-inflammatory, antipyretic effect and inhibits the process of bonding (aggregation) of platelets, that is, the formation of blood clots. In addition, aspirin selectively inhibits the synthesis of thromboxane A2, which facilitates bonding of platelets - this leads to a decrease in platelet aggregation and reduce blood clotting.

However, aspirin has a strong side effect: it inhibits the action of the enzyme cyclooxygenase (COX), which are formed under the influence of biologically active substance prostaglandins which protect the gastric mucosa against various impacts. Therefore, taking aspirin often develop chronic erosive gastritis and peptic ulcer.

To eliminate this side effect of the introduced cardiomagnyl magnesium hydroxide, which protects the gastric mucosa against aspirin.

Who should receive cardiomagnyl

Prophylactic administration cardiomagnyl recommended to patients suffering from diseases such as diabetes mellitus Diabetes - threatening and incurable disease , Obesity, lipid metabolism, hypertension (high blood pressure) and some others. Particularly welcome is shown cardiomagnyl elderly people and smokers. It is the prevention of thrombosis and blood vessel complications such as myocardial infarction, ischemic stroke, and others.

Cardiomagnyl administered in case of myocardial infarction has been, for the prevention of recurrent disease. In addition, it is prescribed for frequent attacks of angina.

During surgery on the heart and blood vessels (for example, in coronary artery bypass surgery) for the prevention of venous thromboembolism also appointed reception cardiomagnyl (thromboembolism - a detachment of the thrombus, the movement of his bloodstream through the blood vessels and the obstruction of their vessel, which may be far from the formation of a blood clot) .

Contraindications

Admission cardiomagnyl contraindicated:

• in hemorrhagic stroke (rupture of a blood vessel supplying blood to the brain);
• while reducing the clotting ability of the blood and tendency to bleeding from any source;
• when "aspirin" asthma, which occurs when taking NSAIDs;
• when erosive gastritis and gastric ulcer and duodenal ulcers, as well as gastrointestinal bleeding;
• with severe kidney disease with severe violation of their functions;
• in certain enzyme disorders (deficiency of glucose-6-phosphate dehydrogenase)
• Pregnancy in I and III trimesters of pregnancy and during the feeding of the child Breastfeeding - a personal choice   breast;
• in childhood and adolescence - the reception is only allowed to 18 years old;
• if you are hypersensitive to the drug;
• It can not be combined with methotrexate cardiomagnyl reception.

With caution is prescribed for gout cardiomagnil Gout - the "disease of kings" , Gastric ulcer and duodenal ulcers, as well as gastrointestinal bleeding in patients in the past, liver failure, all allergic diseases, nasal polyposis, in the II trimester of pregnancy.

Side effect

Cardiomagnyl can give the following adverse reactions:

• allergic reactions (often encountered) - urticaria, angioneurotic edema, rare - anaphylactic shock;
• from the gastrointestinal tract - heartburn, nausea, vomiting, pain in the upper abdomen, erosive and ulcerative lesions of the mucous membrane of the stomach and duodenal ulcers, bleeding from the stomach and intestines, ulcer perforation of the stomach or duodenal ulcers, inflammation of the mucous membranes of the mouth ( stomatitis), esophagus (esophagitis), colon (colitis), irritable bowel syndrome;
• from the liver - a transient liver function abnormalities;
• by broncho-pulmonary system - bronchospasm;
• from the blood - increased bleeding, reduction of blood clotting, anemia, low platelet and granular leukocytes in the blood (sometimes complete absence - agranulocytosis, which leads to a drastic decrease in immunity), increase in the number of eosinophils (sign sensitization);
• the nervous system - dizziness Dizziness - if the ground is slipping from under his feet , Headache, insomnia or drowsiness, tinnitus, very rarely - hemorrhagic stroke.

Cardiomagnyl - it is a good tool for the prevention of thrombosis, but the doctor must prescribe it.

Galina Romanenko