Cardiomagnyl - a drug which includes the first nonsteroidal anti-inflammatory drugs (NSAIDs) - aspirin. Aspirin has many contraindications, as is able to exert significant side effects. Therefore, even in order to prevent it you need to take after the test.
Features action cardiomagnyl
Side effects and contraindications cardiomagnyl for its reception characteristics derive from its actions. As NSAID aspirin has anti-inflammatory, analgesic and antipyretic activity. In addition, it reduces the ability of blood platelets to stick together, i.e. prevents the formation of thrombi.
The action of aspirin is based on the fact that it suppresses the activity of the enzyme cyclooxygenase (COX), which affects the synthesis of prostaglandins.
Some prostaglandins are active participants in the inflammatory process, other prostaglandins also protect the stomach lining from external influences. Under the effect of aspirin decreases the synthesis of prostaglandins, including those that protect the gastric mucosa - this is what provides the main side effects of the drug. In addition, by inhibiting COX blocked synthesis of thromboxane A2 - it helps reduce the aggregation (agglutination) of platelets.
The structure other than aspirin cardiomagnyl includes magnesium hydroxide, whose mission - to protect the stomach lining from the effects of aspirin.
Contraindications of the gastrointestinal tract
Despite the fact that the magnesium hydroxide is largely flattens adverse effect of aspirin on the mucosa of the gastrointestinal tract, it completely this side effect is not eliminated.
As a side effect cardiomagnyl is irritating to the mucous membranes of the gastrointestinal tract, it is not suitable for receiving any erosive and ulcerative processes in this field in the acute stage. That is, chronic erosive gastritis, gastric ulcer and duodenal ulcer gastritis, as well as bleeding from the stomach and intestines.
The caution should be applied cardiomagnil even if erosive and ulcerative processes or bleeding from the gastrointestinal tract of the patient are in the past, and then the disease for a long time in a state of stable remission.
Contraindications for increased bleeding
Cardiomagnyl inhibits platelet aggregation and thereby reduce the clotting ability of blood. Therefore, before prescribing this drug it is very important to be sure that the patient does not reduce these figures and there is no tendency to bleed. Causes of increased bleeding may be different, but in any case take cardiomagnil such patients can not.
If such patients will be assigned cardiomagnil, then they will increase the tendency to bleed, including an internal, for example, with the development of ulcer process in the gastrointestinal tract.
Contraindications cardiomagnyl the part of the brain
Cardiomagnyl is a means to prevent the development of ischemic stroke, which can occur when a sharp narrowing or thrombosis
Thrombosis - the cause of heart attack and stroke
blood vessels of the brain. But in hemorrhagic stroke
Stroke - a serious brain injury
cardiomagnil contraindicated, since this type of stroke develops when a blood vessel rupture and penetration of blood into the brain tissue. When blood clotting is reduced, the bleeding will be more extensive, so in this case the patient is prescribed styptic.
Contraindications for allergic diseases
Many of the NSAIDs cause or exacerbate allergic reactions, however their use is not desirable in all allergic disorders. Very often in response to aspirin bronchospasm occur. This phenomenon even has been called "aspirin" asthma. Contraindications cardiomagnil when allergic rhinitis, atopic dermatitis and other allergic diseases.
Contraindications for kidney and liver
In severe kidney disease with severe renal insufficiency
Kidney failure - when treatment is vital
cardiomagnil appoint not recommended, since the decrease in renal function is disrupted the process of removing from the body of aspirin.
If kidney function is significantly impaired, the cardiomagnil used with caution. By reducing liver function will also need to be careful when taking cardiomagnyl.
Other contraindications for receiving cardiomagnyl
Cardiomagnyl should not be prescribed during pregnancy (aspirin can cause congenital malformations), while feeding the baby
Breastfeeding - a personal choice
feeding, at the age of 18 and are hypersensitive to its components.
Furthermore, it can not be used concurrently with methotrexate - a drug that inhibits the action of folic acid and thus prevents the growth of malignant tumors. This drug has similar side effects as cardiomagnil.
Cardiomagnyl - this is a good preventative tool, but not quite safe, so it should be prescribed by a doctor.