Watching women with endometriosis showed that hormone begins to decline when the ovarian activity, that is, during menopause, endometriosis in most cases regress. But not all so simple: sometimes this is the age for the first time there are signs of endometriosis.
Why during menopause are signs of endometriosis
Endometriosis - a disease which is based on two factors: hormonal disorders and immune disorders. Violations occur in hormonal levels in the body an excess of female hormones estrogen and the lack of another female sex hormone - progesterone and pituitary gonadotropins. Estrogen hormone support performed in the first half of the menstrual cycle, during which the maturation of the egg in the ovary and the growth of the mucous membrane of the uterus (the endometrium).
Normally after oocyte maturation hormonal changes, the pituitary gland starts to secrete luteinizing hormone, which occurs under the influence of ovulation
Ovulation - How to determine as accurately as possible?
(release of an egg from the ovary), and then, on the site of the ruptured follicle begins to operate the new endocrine gland the corpus luteum, which produces progesterone
Progesterone - norm and pathology
. Progesterone inhibits the secretion of estrogen and the growth of the endometrium, causing it to secrete a secret.
In endometriosis the first half of the menstrual cycle lasts a long time because of the large amounts of estrogen and progesterone lack. The endometrium is growing too, and when hormonal support is reduced gradually rejected, accompanied by prolonged bleeding. During this bleeding endometrial cells or pieces thrown into other organs and tissues and begin to grow there, forming endometriosis. This happens not all women, but only those who have impaired immunity. Land endometriosis in other organs behave exactly the same way as the endometrium in the uterus, they then rejected, then expand under the action of sex hormones.
Most often endometriosis develops in the child-bearing age, as cyclical changes in a woman contribute to the widening of its foci. But often endometriosis can be seen during adolescence. It is thought that during menopause due to a decrease in the amount of estrogen in the body and the gradual reduction of cyclic changes endometriosis regress.
Today, these principles built conservative treatment of endometriosis: using various drugs create an artificial menopause, which gradually leads to the disappearance of symptoms of endometriosis
Symptoms of endometriosis - can be very different
.
Do I always have symptoms of endometriosis are reduced during menopause
Unfortunately, there are cases where during menopause endometriosis was shown for the first time or actively recur. This suggests that the disease is a cause, hitherto not fully understood.
Great chance to "earn" during menopause endometriosis in women suffering from obesity and diabetes. And also, this mechanism is not fully understood. It is known, for example, that for reducing ovarian estrogen fat cells start to secrete that supports existing hormonal disturbances, as the amount of progesterone is not increased. Sometimes the amount of estrogen is so great that during menopause there are the first areas of endometriosis or existing endometriosis begins to actively spread. Thus, dysfunctional uterine bleeding
Uterine bleeding outside of menstruation - a sign of a serious breach
Typical of the period of menopause sometimes have endometriosis.
But so far it is not clear how endometriosis develops during menopause diabetes.
The difficulties of diagnosis and treatment endometroza during menopause
Since during menopause there is a decrease in estrogen secretion, some doctors believe that during this period the symptoms of endometriosis should go on the decline. This leads to late diagnosis of progressive forms of endometriosis and the weakening of the woman's body from constant bleeding.
Like any other disease, endometriosis is best treated in the initial period. If the disease is allowed to proceed for a number of years, it is much more difficult to treat and tend to the constant recurrence.
In addition, during the menopause and menopause increases the risk of transformation in the areas of endometriosis cancer (malignancy). This process can be stimulated by the woman receiving estrogen alone without progesterone reception.
Endometriosis can occur during menopause, why - this question has no definitive answer.
Galina Romanenko