Female sex hormone estrogen affects all types of metabolism, including carbohydrate and fat metabolism. All this contributes to both increase and decrease in blood sugar. The development of diabetes does not exclude the possibility of hypoglycaemia - a sharp decline in blood sugar.
Effect of estrogen on metabolism
Estrogens primarily affect lipid metabolism, reducing the intensity of metabolic processes. This leads to the formation of a so-called central or visceral obesity, wherein the fat is stored in the waist and internal organs. The adipose tissue is an active synthesis of female sex hormones, so women have to menopause overweight, menopause occurs later.
At the same time disturbed carbohydrate metabolism
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: Cells of various organs and tissues become less sensitive to insulin (insulin resistance), which promotes the absorption of glucose by cells - the main source of energy. As a result, the blood accumulates much insulin and glucose, which contributes to the formation of the second type of diabetes, in which glucose levels are many, but it is not absorbed by cells because they are less sensitive to insulin. In addition, with insufficient intake of estrogens in the blood increased glucose production in the liver.
Effect on visceral obesity amount of glucose in the blood
Visceral obesity contributes to the formation of insulin resistance. This happens because the fatty tissue of the internal organs has a direct effect on the liver and more actively involved in metabolism than subcutaneous fat. It allocates biologically active substances which act on the liver to form insulin resistance.
Such violations of metabolic processes contribute to high blood pressure, body weight gain, increased blood cholesterol levels that. This further worsens the carbohydrate metabolism.
Glucose is vital cells of the human body for them to exchange processes. Especially needed glucose to the brain cells. Therefore, the cerebral cortex precisely control the content of glucose in the blood and if it is not enough, includes additional mechanisms of its receipt.
Why during menopause may develop hypoglycemia
Hypoglycemia develops when the human body is more insulin than is currently required. When menopause blood may contain a lot of insulin, which can not perform their functions to improve glucose uptake tissues. However, since normally high levels of insulin are always associated with low blood glucose, with insufficient intake of glucose in tissues include contrainsular mechanisms - the release of substances (stress hormones
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For example, epinephrine and glucagon, favors the formation of glucose from glycogen reserves are stored in the liver). Under the influence of these substances liver glycogen is cleaved, and further portions of the blood to glucose.
Since menopausal estrogen may be fluctuations in the amount of blood, together with them, increases or decreases in the blood glucose content and degree of assimilation of its tissue cells. This can lead to both an increase in blood sugar
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(hyperglycemia), and to a sharp decrease (hypoglycemia).
Symptoms of hypoglycemia
Insufficient intake of glucose to the brain cells is accompanied by a sudden change in mood, irritability, weakness, fatigue, severe hunger, dizziness, visual disturbances (blurred perception of objects), the feeling that "feet do not hold." When the mechanisms counterregulation appear such symptoms as tremors in the limbs first, and then throughout the body, sweating, heart palpitations, pallor, anxiety and fear. Sometimes there are sensory disturbances in the form of "pins and needles on the body", numbness of the limbs.
If despite all the efforts of the organism in the blood glucose level does not rise, there comes a starvation of the brain cells - it becomes really dangerous, because the outcome could be a hypoglycemic coma with irreversible changes in the brain cells. Signs of incipient hypoglycemic coma is a violation of concentration, speech, coordination of movements. Often there is an increased agitation, which was then replaced by impairment of consciousness up to its complete loss, seizures, strokes.
At the first signs of hypoglycemia
Lowered blood sugar - hypoglycemia signs
urgently need to eat something sweet, for example, two or more pieces of candy sugar. Repeat intake of sugar can be a quarter of an hour, if the condition has not improved. If this does not work, then you need to call an ambulance.
At menopause every woman should control blood sugar, especially if she has any symptoms of menopause.
Galina Romanenko