Ginepriston - not a panacea

January 21, 2010

 Contraception in today's society is an essential element of daily life. Virtually every pharmacy can be found a whole arsenal of contraceptives, but the most reliable of them are undoubtedly hormonal contraceptives. Indeed, the effectiveness of such drugs is 98 - 99 percent. According to this indicator with hormonal contraception Hormonal contraception: Modern birth control pills  Hormonal contraception: Modern birth control pills
   It can not match any of the known methods of protection against the possible occurrence of pregnancy.

It is not surprising, given that the female body hormones play a major role in the emergence and development of pregnancy. First and foremost among these hormones progesterone should be noted. The significance of progesterone in this respect can not be overemphasized. This hormone is involved in all stages of pregnancy, and even dozachatochny period.

  • Firstly, progesterone promotes the release of an egg from the ovarian follicle.
  • Secondly, due to reduction in progesterone enhanced ciliary epithelium of the fallopian tube through which the egg moves into the uterus.
  • Third, the hormone stimulates proliferation (proliferation) of the mucous layer of the uterus, preparing the necessary conditions for the attachment of a fertilized egg to the uterine wall.

Furthermore, progesterone Progesterone - norm and pathology  Progesterone - norm and pathology
   inhibits muscle activity of the uterus, ie it reduces the tone of her muscles. This is reasonable, since excessive contractile activity of uterine smooth muscle can easily lead to miscarriage and placental abruption Miscarriage - can you protect yourself from it?  Miscarriage - can you protect yourself from it?
 . Finally, progesterone inhibits the immune system The immune system - how it works?  The immune system - how it works?
   mother, chasing one holy goal: the preservation of the child. Otherwise, the antibodies of the female body, perceiving the developing fetus as a foreign biological object, can not only cause him serious harm and contribute to congenital diseases, and even lead to intrauterine death of unborn babies.

Now it becomes clear that the lack of progesterone makes it impossible for the normal development of the pregnancy and even its occurrence .  It is based on this and the action of certain oral contraceptives, in particular - ginepristona .  This drug did not inhibit the formation of progesterone .  The mechanism of action is different ginepristona .  Namely, in blocking interactions with progesterone receptors susceptible to the uterus .  After all, a hormone shown to its biological activity, you must have two components .  The first component - a hormone itself, and the second indispensable condition - a specific receptor, ie the nerve ending, which the hormone can interact .  It was on this second unit and directed action ginepristona .  As a result of the endometrium loses its ability to proliferate without which the egg is unable to penetrate the wall of her .  If the mucous membrane has already taken the necessary size for the implantation of the egg, ginepriston enhances uterine activity and promotes delamination hypertrophic mucosal sites .  That is why the drug can be used regardless of the phase of the menstrual cycle .

Ginepriston must be taken not later than three days after the end of the "unsafe" sex. During the two hours before and after the same amount of time the drug is eliminated any food. Otherwise, the guarantee of its effectiveness is reduced.

However, it should be remembered that ginepriston - it is not a means for daily contraception. The drug can only be seen as a measure of emergency prevention, first aid at the "accident" case (for example, damage the condom). If ginepriston used too frequently, its protective efficacy is rapidly declining. Accordingly, increasing the likelihood of pregnancy. In addition, as virtually any drug ginepriston has certain side effects. These include discomfort in the lower abdomen, bloody discharge, fever, nausea and sometimes vomiting.

To receive ginepristona there are specific contraindications, for example, renal hepatic pathology, hormonal dysfunction and other diseases. Therefore, before using the drug should consult a doctor.

Zhiguli Andrew

Article Tags:
  • ginepriston

Jeanine - side effects are possible

December 9, 2011

 Jeanine - side effects
 Side effects are at all hormonal contraceptives. Janine relates to a low-dose hormonal contraceptives, however, and it gives a lot of side effects. To avoid them, you need to apply Jeanine only on prescription, and after the test.

 Jeanine - side effects are possible

Why conduct a survey before the appointment of Janine

Before the appointment of any contraceptive gormoalnogo (CC) must be conducted a general survey, which includes not only the gynecological examination and laboratory tests, and consultation with other professionals in order to avoid diseases in which the reception of the Civil contraindicated.

Despite the fact that Janine is a low-dose drug, the manufacturer (the German pharmaceutical company Schering) insists on the mandatory implementation of this condition. Only in this way can be guaranteed safety of Jeanine women.

 Jeanine - side effects are possible

Side effects Jeanine side of the circulatory system

The main danger when taking Jeanine (as when receiving any other GC) is thrombosis - blockage of blood vessels clots. And, despite the fact that practically all drugs Schering give a minimum of side effects, however, the danger always exists. It therefore is in the contraindications for administration of the drug constitute almost half of the disease, which could cause an increased tendency to thrombosis.

Thrombosis dangerous that may occur in any blood vessel, including the supply vital organs. Especially dangerous thrombosis of blood vessels that feed the heart, brain and abdominal organs. Another danger - thromboembolism - separation of thrombus and occlusion of their major blood vessels, such as pulmonary arteries.

An increased tendency to form blood clots can cause any disease, creating congestion in the circulatory system. The stagnation in the venous system creates varicose veins, with thrombosis may occur in the lower limbs and abdominal organs.

Atherosclerosis can be a cause of coronary heart disease and narrowing of the blood vessels of the brain. Congestion may occur in the arterial system due to blood vessels that are narrowed because of the formation on the walls of atherosclerotic plaques. Thrombosis of the coronary arteries can lead to myocardial infarction, and vascular brain - a stroke.

Increased blood clots characteristic of diabetes with vascular complications, various diseases of the pancreas Diabetes and pancreas - the things you need to know  Diabetes and pancreas - the things you need to know
   and some other diseases. Before the appointment of Janine necessarily verified all indicators of blood clotting.

 Jeanine - side effects are possible

Side effects Jeanine from the digestive organs

The risk of changes from the side of the liver resulting from the taking Jeanine, so it is not suitable for all diseases of the liver with the violation of its functions. Appoint Janine Jeanine - not only contraception but also protection against acne  Jeanine - not only contraception but also protection against acne
   only after complete recovery and normalization of laboratory values. When the first signs of liver dysfunction (eg jaundice) Jeanine should be abolished.

For part of the gastrointestinal tract may cause nausea, vomiting, diarrhea, abdominal pain. These side effects often take place over time and does not require the abolition of - in this case, the decision to continue or discontinue hormonal contraception Hormonal contraception: Modern birth control pills  Hormonal contraception: Modern birth control pills
   The surgeon.

 Jeanine - side effects are possible

Side effects of Jeanine in the nervous system and sensory organs

On the part of the central nervous system may be a headache (including headache on one side - a migraine that occurs when the sharp expansion of blood vessels of the brain), low mood, fatigue. Especially dangerous are migraines that are accompanied by short-term or more persistent movement disorders and sensitivity.

Violations of the senses often manifest visually impaired and intolerance of contact lenses.

 Jeanine - side effects are possible

Side effects Jeanine from sexual and endocrine systems

On the part of the endocrine system may cause painful tension of the mammary glands, discharge from the nipples, edema (fluid retention due to violations under the influence of the endocrine system of salt metabolism), to increase or, conversely, decrease in body weight, the appearance of age spots on the face (chloasma).

On the part of the reproductive system may change the nature of vaginal discharge Vaginal discharge: normal or disease?  Vaginal discharge: normal or disease?
   and sexual desire.

There may be side effects such as allergies, which manifest themselves in the form of various types of skin rashes, itching, burning, angioedema.

Jeannine - a quality hormonal contraceptive, which is produced by a reliable pharmaceutical company. Nevertheless, as with any drug of this group, it may give serious side effects if when administered were accounted for receiving all contraindications.

Galina Romanenko

Article Tags:
  • Janine