Mirena Intrauterine therapy system has been successfully used in the treatment of certain types of endometriosis, since steadily releases small doses of hormones, thereby inhibiting, growth of the mucous membrane of the uterus (the endometrium). Today, such treatment is often used in endometriosis of the uterus.
How does endometriosis Mirena
Mirena is a hormone-white elastomeric core, placed in a special box covered with an opaque membrane, regulating the release of active principle intrauterine therapeutic system - levonorgestrel. The housing has at one end a loop, which are attached to the filament to remove Mirena. Releases MIRENA known German pharmaceutical company Bayer.
After the introduction of Mirena in the uterus begins to slow at a constant speed of releasing levonorgestrel - a synthetic analogue of the female sex hormone progesterone
Progesterone - norm and pathology
. A feature spiral action is that it has a mainly local actions which require lower doses of hormones than when taken orally
The main effect of Mirena is to suppress the proliferation of the mucous membrane of the uterus (the endometrium).
The constant presence of Mirena in the uterus leads to the fact that in endometriosis regulated menstrual cycle, the duration and decreases the amount of menstrual and intermenstrual bleeding, decreased pain. In some cases mild forms of endometriosis uterus observed regression of lesions up to a full recovery.
Thus immediately after installation Mirena may increase bleeding and spotting, but then (usually within one to three cycles) reduces blood loss by regulating the menstrual cycle, and less prolonged and heavy menstruation. Sometimes menstruation ceases altogether, which is a positive factor for endometriosis, as it is cyclical changes in the uterus contribute to the spread of the disease and its recurrence after treatment.
Mirena also causes an inflammation limited to the uterus, resulting in the uterine cavity is formed by an acidic environment with an increased number of leukocytes, which hampers the promotion of sperm. This may create a risk of infectious-inflammatory process in the uterus.
Do Mirena side effects and how dangerous they are for endometriosis
Mirena - a low-dose hormonal system, so it has side effects dramatically. But sometimes still appear nausea, headache, depression
Depression - a little more than a bad mood
Irritability - you try to control my temper
, Painful swelling of the breasts, small irregular menstruation, acne
Acne: facial trouble
, Hair loss, increased body hair, urticaria, back pain. These side effects do not require the removal of the spiral and tested independently for several menstrual cycles. In endometriosis, they are not dangerous, in fact, cessation of menstruation carries therapeutic function in this disease.
In some cases, self-helix is removed from the uterus, even more rarely perforation (perforation) of the uterus, the development of ectopic pregnancy - such complications could theoretically arise with the introduction of any intrauterine devices, including from the Mirena.
Really significant side effects can be thrombosis - this sometimes happens when using progestogen, therefore, against the background of Mirena in women showing signs of varicose veins or thrombophlebitis, she should see a doctor.
Sometimes the background Mirena in the uterus developing inflammatory processes, this rarely happens, but requires the removal of the spiral.
When MIRENA install contraindicated
Contraindications to set the Mirena are:
- individual intolerance of components;
- pregnancy and lactation;
- Any inflammatory and infectious gynecological, urology, proctology processes, including postpartum endometritis, infected abortion;
- oncological diseases;
- cervical dysplasia;
- vaginal bleeding of unknown origin;
- lowered immunity and susceptibility to common infectious and inflammatory diseases;
- any structure uterine disorders both innate and acquired nature, including adhesion in the uterus;
- severe liver disease in violation of its functions.
In any case, the decision and the introduction of Mirena endometriosis takes the doctor after a thorough examination of women. In severe cases of endometriosis MIRENA is usually not used. But it can be used for suppression of recurrence of the disease after the active hormonal therapy or following surgery.
Mirena is a hormonal contraceptive quality, which is now often used to treat certain types of endometriosis.