Follicular thyroid adenoma - is difficult to distinguish from cancer

February 20, 2013

 follicular thyroid adenoma
 Follicular thyroid adenoma - a benign tumor, the cells of which are very similar to cancer cells - follicular adenocarcinoma. In most cases to distinguish benign from malignant tumor in its cytology (studied material taken using the puncture of the thyroid gland) is not possible.

 Follicular thyroid adenoma - is difficult to distinguish from cancer

What is a follicular neoplasms of the thyroid gland

For follicular thyroid tumors are tumors in the structure which is dominated by follicular cells. These diseases are a distinct group of practical considerations. The fact that one of the main methods of any studies in thyroid gland The thyroid gland - is responsible for your hormones  The thyroid gland - is responsible for your hormones
   a needle aspiration biopsy (FNA), during which the assembly of the thyroid gland under the control of the ultrasonic beam takes the contents (usually a group of diverse cells) and examined in the laboratory under a microscope cytology.

If cytology detected prevalence of follicular cells, one speaks of follicular neoplasms. But the problem is that the microscopy practically impossible to distinguish between a benign tumor cells from cancer.

The vast majority of follicular neoplasms are benign tumors - follicular adenoma, malignant follicular adenocarcinoma occur approximately ten times less.

Nevertheless, the physician, cytologist conclusion about the nature of follicular tumors, is wariness against cancer and will not allow the patient to delay the operation. During the operation (while the patient is on the operating table) excised tissue are given for histological examination, during which already exactly determined by the nature of the tumor and on the results of this analysis depends on the volume of surgery (removed portion of the breast or completely all iron to nearby lymph nodes).

 Follicular thyroid adenoma - is difficult to distinguish from cancer

What are the symptoms of thyroid follicular adenoma

Follicular adenoma is a benign tumor consisting of a mass of follicles (cells of its own thyroid tissue - thyrocytes) enclosed in a connective tissue capsule. Follicular Adenoma not germinate in the capsule and the surrounding tissue, including blood vessels.

In most cases, no follicular adenoma produces thyroid hormones Thyroid hormones: mechanism of action and physiological effects  Thyroid hormones: mechanism of action and physiological effects
 So at small sizes it does not manifest itself and is a random finding in the prophylactic examinations and during the ultrasound. If the size of large adenomas, it deforms the neck and the patient may find it yourself. Furthermore, a large adenoma begins to compress the surrounding tissue (esophagus, trachea, blood vessels, nerve trunks), causing disordered breathing, swallowing, circulatory and pain (if the compressed nerve).

 Follicular thyroid adenoma - is difficult to distinguish from cancer

What are the symptoms of thyroid follicular adenocarcinoma

Follicular adenocarcinoma - a malignant tumor of the thyroid. It also incorporates the follicular cells and is surrounded by a capsule, the capsule but does not have clear boundaries such as that of follicular adenoma. However, when tumor palpation distinguish benign from a malignant tumor is often impossible.

One major difference between adenocarcinoma adenoma is its germination in a capsule surrounding veins and tissue, which may be detected during an ultrasound study. Adenocarcinoma also metastasizes Metastasis - danger everywhere  Metastasis - danger everywhere
   in distant tissues - cells spread through the blood vessels.

Sometimes adenocarcinoma from adenoma is difficult to distinguish even during histological examination of the excised tissue. That is why all the follicular neoplasms of the thyroid gland require special vigilance on the part of the doctor.

 Follicular thyroid adenoma - is difficult to distinguish from cancer

Treatment

Treatment of follicular adenoma should be operational life. Since even in the course of surgery and histological examination to distinguish benign from malignant tumors it is not always possible, depending on the location of the tumor nodes held hemithyroidectomy (removal of one of the lobes of the thyroid gland) or total thyroidectomy (removal of the entire thyroid gland). This reduces the risk of recurrence of the disease.

Because after such an operation, the function of the thyroid gland will be reduced, appointed for life, hormone replacement therapy Hormone therapy - is it possible to fool nature?  Hormone therapy - is it possible to fool nature?
 .

Follicular adenoma - a benign tumor that is very difficult to distinguish from cancer.

Galina Romanenko


Article Tags:
  • thyroid adenoma

Thyroxine and alcohol - why take the risk?

January 24th, 2014

 thyroxine and alcohol
 Thyroxine and alcohol combined bad as the one and the other substance may have a negative effect on the cardiovascular and central nervous system. And this can lead to unpredictable consequences - everything will depend on the initial state of the patient.

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What is thyroxine and how it acts on the body

Thyroxine is biologically not very active iodine-containing thyroid hormone, which is in the human body is transformed into the active hormone - triyodtiranin have a significant stimulating effect on metabolism Improves metabolism and losing weight without dieting  Improves metabolism and losing weight without dieting
   and the function of many organs and systems.

In particular, it stimulates the cardiovascular system, causing an overdose tachycardia, cardiac arrhythmias, coronary vasospasm (which nourish the heart muscle) and increase in blood pressure.

Adversely affecting the use of high doses of thyroxine and central nervous system. It causes irritability, anxiety, insomnia.

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The action of alcohol on the body

Alcohol - a toxic substance that adversely affects all the organs and tissues. The extent of such negative effects depends on the dose taken alcohol, his strength and frequency of administration. Direct toxic effects alcohol has on the brain cells and liver.

The negative effects of alcohol can have on the cardiovascular system. Action is usually a two-phase: first, there is an expansion of the blood vessels and then their persistent contraction with a simultaneous increase in blood pressure.

With frequent use of alcoholic beverages may be elevated blood clots and disruption of the coronary circulation.

In addition, alcohol can also have direct toxic effects on the cells of the heart muscle, causing disturbances in their metabolism - myocardial whose symptoms are irregular heart rhythm and heart pain Pain in the heart - always consult a doctor  Pain in the heart - always consult a doctor
 And in the future - cardiovascular failure.

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What can happen on a combination of thyroxine and alcohol

A single dose of weak small doses of alcohol does not usually lead to any negative consequences, so the instruction to L-thyroxine, developed by the German pharmaceutical company Berlin-Chemie, no mention of such a combination.

However, this only applies to people who are not suffering from diseases of the cardiovascular system. Alcohol has, as a direct damaging effect on cardiac muscle cells, and indirectly - via its oxidation intermediates. If the patient suffers from myocarditis or ischemic heart disease, effects on the combination of "thyroxine - alcohol" can have serious consequences. Especially hard it can carry a mix of patients suffering from hypertension - persistent high blood pressure.

But the most dangerous is the use of large amounts of alcohol while taking thyroxine. This can lead to unpredictable consequences on the part of the cardiovascular system, even if the patient had not complained of that body.

The negative effect of the combination of thyroxin with alcohol can be, and the central nervous system. But in this case it will likely affect the frequency and duration of the alcohol abuse. As you know, on this background develop neuroses with increased anxiety, irritability Irritability - you try to control my temper  Irritability - you try to control my temper
 , Aggression and insomnia. All of this will be exacerbated by taking thyroxine.

The negative impact of a combination of thyroxine - alcohol on the liver is also evident. Alcohol has direct toxic effects on the liver cells. Thyroxine is converted to the active triiodothyronine, and then decomposed into products of metabolism in the liver, therefore impaired liver function will always lead to violations of exchange of thyroxine.

Crucial when taking alcohol while taking thyroxine, will certainly have the number and strength of alcohol consumed alcoholic beverage. Even if considerable damage is the combination will bring, at the cellular level, it will reduce the effectiveness of the treatment. So is it worth the risk?

Alcohol is not compatible with most of the drugs precisely because has a toxic effect on the cells of the whole organism. And this in turn contributes to a violation of cellular metabolism and reduce the effectiveness of the treatment. Whether to accept during treatment with thyroxine Thyroxine - the main thyroid hormone  Thyroxine - the main thyroid hormone
   alcohol, each patient decides for himself as contraindications for this instruction is not. But should still think: is it worth?

Galina Romanenko


Article Tags:
  • thyroxine




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