Dekaris and Vermoxum - is effective anthelmintic drugs. But the mechanism of action are different, so different worms exhibit different sensitivities to them. Furthermore, dekaris also has immunostimulatory properties.

The mechanism of action of anthelminthic decaris and Vermoxum

Dekaris (active ingredient - levamisole) causes paralysis of the neuromuscular system round helminths (nematodes) and breaks during their bioenergetic processes. Particularly sensitive to this drug roundworm. Less sensitive intestinal ugritsa (causes strongyloidiasis) and hookworm (hookworm). In addition, dekaris has immunostimulating action, the mechanism of which today finally installed. After ingestion dekaris absorbed into the blood, where it comes into tissue. It decomposes at metabolites in the liver and is excreted mainly in urine.

Vermoxum (active ingredient - mebendazole) selective formation of the desired cells violates round and tape helminths tubulin, which causes inhibition of assimilation of glucose by cells and the formation of ATP from it. As a result of a lack of energy are violated all kinds of metabolism in the cells of the body of worms.

Vermoxum operates mainly in the intestine and then excreted in the feces (90%). The blood is sucked about a tenth of an oral dose. In Vermoxum blood binds to plasma proteins and selectively accumulates in the liver, adipose tissue and cysts formed helminth larvae. Decomposed drug in the liver and excreted in the urine.

What's better?

It all depends on what you need to treat helminth infections. Thus dekaris active against round worms that basically it is used for the treatment ascariasis. But treat other types of parasitic infestations caused by nematodes (roundworms). In addition, dekaris prescribed for violations of immunity as an immunostimulant.

But it has its "preferences" - the best of its impacts are pinworms, and whipworms. But the high efficiency and with respect to the rest of the round and tape worms.

Today, many doctors prefer to prescribe a comprehensive treatment of helminthiasis caused by round worms. In this case, the first once appointed dekaris that paralyzes and weakens the worms and then, after a few days - and once Vermoxum that they finally "finishes."

Side effects

When receiving decaris may experience the following side effects:

• the central nervous system - irritability Irritability - you try to control my temper , Insomnia, low mood, very rarely - about a month after receiving decaris developing encephalopathy - persistent changes in the brain;
• the part of the digestive system - decreased appetite, nausea, vomiting, diarrhea or constipation, stomatitis, rarely - acute pancreatitis (inflammation of the pancreas);
• From the senses - taste disturbances and olfactory perceptions;
• from the skin - skin rashes of various nature;
• on the part of the musculoskeletal system - pain in muscles and joints;
• Hematopoietic system - reducing the number of levels of granular white blood cells (agranulocytosis - leads to decreased immunity) and platelets (reduced clotting ability of the blood);
• flu-like symptoms - fever, weakness, malaise.

No fewer side effects and Vermoxum:

• the part of the digestive system - nausea, vomiting, diarrhea, abdominal pain Abdominal pain: Types and Symptoms , Abnormal liver function;
• the central nervous system - dizziness and headaches;
• Hematopoietic system - agranulocytosis (decrease in the number of granular white blood cells and decreased immunity), eosinophilia (an increase in the number of one type of white blood cells - eosinophils, which speaks of an allergic mood of the body), anemia (a decrease in blood hemoglobin and red blood cells);
• by the kidneys and urinary tract infections - blood in the urine;
• allergic reactions, alopecia.

Contraindications

Contraindications for treatment dekaris Dekaris - with anthelmintic drug and immunostimulatory effects   They are:

• agranulocytosis, which was called at any time in the past, any drugs;
• Children under three years of age;
• breast-feeding;
• are hypersensitive decaris.

Dekaris wary appoint patients with impaired liver and kidney function, as well as pregnant women.

Admission Vermoxum is contraindicated in:

• ulcerative lesions of the intestine;
• hepatic dysfunction;
• pregnancy, breast- Breastfeeding - a personal choice   chest and for children up to two years;
• are hypersensitive Vermoxum.

When treating dekaris Vermoxum and can not drink alcohol.

Dekaris and Vermoxum - effective anthelmintic drugs, but each of them has its own indications and contraindications, to understand that only a doctor can.

Galina Romanenko

Vermoxum - an effective anthelmintic drug. As with any effective medication, he has a number of contraindications and side effects. Therefore Vermoxum used only on prescription. Separate uncontrolled treatment can lead to complications.

How does Vermoxum

Because the mechanism of action of drugs derive their side effects and contraindications for use. Vermoxum suppresses all types of metabolism Metabolism: The basis of life of all living things   have worms. It is also partly (10%) is absorbed into the blood accumulates in the wrist formed by the larvae of worms and destroys them. Moreover, it is actively binds to plasma proteins and accumulates in the liver. This may cause some side effects, especially if the patient decreased hepatic or renal function. In addition, Vermoxum may cause allergic reactions.

Adverse effects that may arise in treating Vermoxum

When treating Vermoxum can occur a number of undesirable (adverse) effects. In most cases, side effects are caused by the digestive system, especially if a lot of large intestine helminths (e.g., ascarids). After death, they can clog the lumen of the intestine, causing abdominal pain, nausea, vomiting, constipation and diarrhea. Very rarely ileus may occur.

Changes in the gastrointestinal tract may occur with long-term uncontrolled reception Vermoxum. It nausea, vomiting, abdominal pain Abdominal pain: Types and Symptoms , Diarrhea and constipation. Furthermore, in this case there are changes in liver function, which appear a temporary increase in liver enzymes (changes in laboratory parameters). Sometimes there is a small yellow skin and sclera. At long courses of treatment for echinococcosis in a few cases there were hepatitis (liver inflammation).

Central nervous system side-effects are rare, they manifest dizziness and headache.

Significant changes during chronic administration Vermoxum can be observed on the part of hematopoiesis. This reduction in the total number of white blood cells (WBCs), mainly neutrophils, which are responsible for the state of cell-mediated immunity. This leads to decreased immunity, resulting in the patient begins to get sick often colds, it has exacerbated all infectious and inflammatory processes.

At the same time there is an increase of allergic disposition of the body, which manifests itself in the form of increased levels of one type of white blood cells - eosinophils. All these processes contribute to the formation of infectious and allergic processes, prone to long duration.

Long enough toxic effects also inhibits the synthesis of red blood cells and the formation of hemoglobin, causing anemia.

With prolonged use Vermoxum also possible changes in the kidneys and urinary tract - appear in the urine blood and other elements showing pathological changes in the kidneys.

Prolonged use Vermoxum may also cause a significant loss of hair.

Allergic reactions while taking Vermoxum often manifest themselves in the form of various skin rashes and angioedema. But it is possible and severe allergic reactions such as anaphylactic shock.

This treatment is contraindicated Vermoxum

Since the possible side effects from the gastrointestinal tract, including obstruction of the intestinal lumen helminths Vermoxum strictly forbidden to appoint any erosive and ulcerative processes in the intestine - is mainly ulcerative colitis and Crohn's disease.

Also, you can not use Vermoxum in the human liver, as it is in the liver is decomposed Vermoxum to exchange products. If abnormal liver function Vermoxum will linger in the body and have a toxic effect on it, the first to suffer liver cells - perhaps even a serious complication such as hepatitis Hepatitis - the scourge of our time .

The official manual says nothing about whether it is possible to apply Vermoxum renal impairment. However, it is through the kidneys displayed Vermoxum, who was in the blood and in violation of their functions removing it will be broken.

Vermoxum not use during pregnancy, while feeding the baby Breastfeeding - a personal choice   chest and for children up to two years. This can not be done because Vermoxum platsentrarny can pass the barrier and have a negative impact on the fetus. Since it enters the bloodstream, it stands out with mother's milk, and to infants and children up to two years, it can not be used due to significant side effects.

Vermoxum Not applicable also in the case if the patient exhibits increased sensitivity to the components of the drug.

Vermoxum - highly effective anthelmintic drug that has a number of side effects and contraindications for the treatment, so it should be administered only by a physician.

Galina Romanenko