Diseases of the digestive system often develop on the background of the high acidity of gastric juice. In such cases, part of the complex treatment of patients often include omeprazole. Omeprazole can significantly alleviate the condition of patients, which is always concerned about pain in the abdomen Abdominal pain: Types and Symptoms Heartburn and acid regurgitation Belching: why it happens and that means .

The use of omeprazole for stomach ulcers and duodenal ulcers

Peptic ulcer and duodenal ulcers are almost always develops against the background of increased gastric secretory function. Too acidic environment erodes the mucosa of the stomach and duodenum. The acidic environment is also favorable for the life of the causative agent of peptic ulcer disease Helicobacter pylori. These bacteria during the life recovered ammonium, which neutralizes acidic medium. By lowering the acidity is neutralized and ammonia is not toxic to the bacteria themselves.

When ulcer omeprazole reduces the acidity by acting on the secretion of hydrochloric acid at the cellular level. As a result of gastric mucosa is not easily provoked, and for the pathogen are uncomfortable conditions.

For antibiotics (they are used to destroy Helicobacter pylori) is weakly acid and alkaline medium are, on the contrary, comfortable. Therefore, in the combined treatment yazvennoybolezni today almost always include omeprazole, especially if in the course of examination was detected Helicobacter pylori.

Take omeprazole once a day before eating in the morning. In gastric ulcer and 20 or 40 mg on reception within a month. If there is an improvement, but not completely healed ulcer, then repeat the treatment. When duodenal ulcer the same dose of omeprazole is made within two weeks and, if necessary, repeat the course.

If the purpose of treatment is to remove from the organism Helicobacter pylori, the omeprazole 20 mg administered twice a day for two weeks together with antibacterial drugs.

Omeprazole at reflux oesophagitis

Between the esophagus and stomach is circular muscle - the sphincter, which closes the possibility of falling acidic stomach contents into the esophagus. But in some cases not work and the sphincter of the stomach contents into the esophagus, irritating its walls. If the acidity of gastric juice increased, inflammation in the esophagus develops quickly and runs hard. This disease is called reflux esophagitis.

The walls of the esophagus when reflux esophagitis first inflamed, then the inflammatory process can be purulent with the formation of multiple small abscesses and abscesses. Pustules are opened and the surface of the wall of the esophagus is covered with sores. Possibly even perforation of the esophageal wall, and bleeding from the blood vessels feeding the esophagus.

Patients at reflux esophagitis experiencing terrible suffering. They worry about constant heartburn that goes into burning and chest pain, acid regurgitation. In the later stages of the disease, along with masses of food to regurgitate blood clots and pus.

Omeprazole can alleviate the condition of patients with reflux esophagitis: reduced gastric acidity will reduce heartburn and irritation of the stomach wall, which ultimately will contribute to the remission of the disease.

Omeprazole prescribed courses of 20 mg once a day for a month. If necessary, treatment can be repeated.

At what other diseases prescribed omeprazole

Ulcerative processes in the stomach wall can be a consequence of stress or reception of various drugs. So, very often develop stomach ulcers in patients with rheumatoid arthritis who regularly take nonsteroidal anti-inflammatory drugs (NSAIDs - aspirin, diclofenac, indomethacin, etc.) To relieve joint pain Joint pain - how to understand what is going on? .

In order to reduce irritation of the stomach wall, so patients prescribed courses of omeprazole. In the treatment of ulcerative process, he was appointed to 20 mg once a day for a month, if necessary, repeat the treatment. For the prevention of ulcer process omeprazole administered with NSAID throughout the course of treatment.

Another indication for receiving omeprazole are diseases of other organs and systems, accompanied by increased secretion. For example, Zollinger-Ellison syndrome - a benign tumor of the pancreas Diabetes and pancreas - the things you need to know Which produces gastrin stimulates gastric acid secretion. The disease can be severe, while omeprazole is assigned individually selected doses, duration of therapy and individual.

Galina Romanenko

Alcohol should not be taken simultaneously with the reception of Motilium as it reduces its medicinal effect. Such treatment is simply useless. But motilium can help vomiting during a hangover, when the body "protest" against the lack of alcohol.

Motilium mechanism of action and the impact of alcohol on him

The mechanism of action Motilium (active substance - domperidone - a dopamine antagonist) is based on blocking dopamine receptor - a neurotransmitter, by which nerve excitation are transmitted along nerve cells. As a result of the mechanism of action is interrupted connection between the stomach and the vomiting center, which is located in the medulla oblongata. This helps stop nausea and vomiting.

At the same time increases the tone and motor activity of smooth muscles of the upper gastrointestinal tract, which promotes food from the stomach into the duodenum. There is also increased tone of the lower esophageal sphincter - it also helps stop vomiting.

Alcohol blocks the action of dopamine antagonists, including the effect of Motilium Motilium - help with the vomiting and impaired motor activity of the stomach . Therefore intake of alcohol will make use of Motilium useless. For example, an overdose of alcohol in healthy people not suffering from chronic alcoholism, begins vomiting - is a protective mechanism that helps to remove the body of any toxins. Remove using a vomiting Motilium impossible.

Motilium in the treatment of alcohol withdrawal syndrome

Alcohol withdrawal syndrome (AS, hangover syndrome) occurs in patients with chronic alcoholism. In healthy people, the hangover does not happen, it should not be confused with the signs of intoxication, which are developed with an overdose of alcohol. AC can be distinguished from intoxication by alcohol effects on the body: the AC is removed by alcohol and intoxication compounded.

AS is associated with the fact that in chronic alcoholism irreversible metabolic disorders Metabolism: The basis of life of all living things , Alcohol becomes vital for its proper functioning. Therefore, separation of alcohol is growing (the progression of chronic alcoholism) disorders as headaches, high blood pressure, shaking the whole body, nausea, vomiting and so on. With a sharp exit from long binge may develop acute psychosis (delirium tremens, delirium tremens).

For the treatment of RCC using various drugs, including to reduce the nausea and vomiting can be used motilium. It is prescribed for one - two tablets (10-20 mg) three - four times a day for half an hour before meals. The maximum daily dose should not exceed 80 mg (8 tablets).

Motilium produced in the form of coated tablets for oral administration, 10 mg, lingual tablets (they are kept in the mouth until the tablet disintegrates and then swallowed with saliva, without drinking water) 10 mg and the suspension (1 ml of a suspension containing 1 mg), which is mainly used to treat children, but it can also be used for adults (one pill Motilium correspond to two teaspoons or 10 ml of suspension).

Contraindications and side effects

Motilium should not be taken in cases of suspected gastro-intestinal bleeding, intestinal obstruction, perforation of the wall of the stomach or intestines, elevated blood pituitary hormone prolactin, simultaneous ingestion of certain medications (eg, ketoconazole, fluconazole Fluconazole - used with caution , Macrolide antibiotics), feeding baby Breastfeeding - a personal choice   breast and hypersensitivity to the components of this drug.

Be wary appoint motilium during pregnancy, the liver and kidney.

Motilium generally well tolerated, however, the side effects associated with its use may arise:

• from the gastrointestinal tract - dry mouth, thirst, diarrhea or constipation, transient intestinal cramps, accompanied by intestinal colic;
• the central nervous system - in case of contact with active substances in the brain may be headache, dizziness, extrapyramidal disorders; extrapyramidal system controls functions such skeletal muscle as posture, muscle tone, muscle willingness to move, fluidity, speed, accuracy and binocular movement; extrapyramidal disorders lead to changes in muscle tone, disturbance of locomotor activity, the appearance of muscle twitching (hyperkinesias) persons lockjaw (lockjaw), or, in contrast, immobility, and combinations thereof; All these violations are taking place after the abolition of Motilium;
• by the endocrine glands - increased secretion of the hormone prolactin by the pituitary gland, which causes release stimulation of breast milk, the menstrual cycle in women and breast enlargement in men;
• Allergic reactions are also possible.

Galina Romanenko