Despite the fact that endometriosis is not yet revealed all its secrets, the disease is now successfully treated. Unfortunately, we can not say that endometriosis can be cured completely and offer complete assurance that its recurrence in the future. But to achieve long-term remission and prevent serious complications such as infertility is quite real.
Treatments for endometriosis
Today, for the treatment of endometriosis is mainly used individually tailored combination therapy consisting of surgical (removal of endometriosis endoscopic method that significantly reduces the risk of adhesion formation) and conservative.
Policy Pay Conservative treatment using various drugs that suppress estrogen, which are the main cause of endometriosis. A disadvantage of the hormonal treatment is that it is effective only during the course of treatment. As soon as these drugs stop taking, relapse is possible. Moreover, artificial menopause, caused by the intake of such drugs can lead to a number of side effects typical of menopause for flares, heart attacks, irritability
Irritability - you try to control my temper
and so on.
For conservative treatment of endometriosis are used synthetic analogs of female sex hormone progesterone (progestin or progestin), combined oral contraceptives, drugs that suppress the production of pituitary hormones and analogues of hypothalamic hormones that suppress the secretion of pituitary gonadotropins and ovarian function.
An example of a progestogen, which is indicated for endometriosis, is djufaston. This drug inhibits the proliferation of the mucous membrane of the uterus (the endometrium) and takes the stage endometrial glands. Thus, partially or completely reduced menstrual cycle that leads to suppression of proliferation areas of endometriosis.
Duphaston is effective only in the initial stages of the disease when pockets endometirioza just appeared. It is often prescribed in cases when a woman wants to have a child, because ovulation does not violate djufaston
Ovulation - How to determine as accurately as possible?
and the woman at the same time has the ability to become pregnant. If pregnancy occurs, it is very good effect on a woman's body: endometriosis does not apply, and in some cases portions endometirioza regress.
Duphaston is usually administered in the form of individually tailored treatments from the fifth to the 25th day of the menstrual cycle
The days of the menstrual cycle: Four phases
for six months or more.
Combined oral contraceptives
Combined oral contraceptives (COCs) containing estrogen and progesterone
Progesterone - norm and pathology
. They are used for endometriosis under the special scheme. When taking COCs as a contraceptive for 21 days followed by one week apart, when endometriosis is recommended to drink them within 63 days (three packages in a row), and then done a week break and repeat the circuit.
Such treatment leads to suppression of ovarian hormonal activity, lack of menses and reduce manifestations of endometriosis.
Drugs that inhibit the production of pituitary gonadotropins
In most cases, for this purpose, danazol, which suppresses pituitary gonadotropic hormone - luteinizing and follicle, thereby terminate proliferation of endometrial tissue. Ovulation is thus also suppressed, but temporarily, only during the course of treatment. While taking danazol reduced menstrual and intermenstrual bleeding and pain, and the areas of endometriosis may decrease in volume.
In danazol have a lot of side effects, as this drug is a derivative of the male sex hormone testosterone. Under the effect of danazol in women can occur several changes of male type: increased hirsutism, acne, weight gain, and so on.
The drugs - analogues of hypothalamic hormones that suppress the secretion of pituitary gonadotropins and ovarian function in the treatment of endometriosis
These drugs are also called GnRH agonists (gonadotropin hormone Riesling). An example of this group of drugs may be Diferelin. Its action is based on the fact that a prolonged stimulation of the hypothalamic pituitary hormones leads to a decrease of its function and to suppression of ovarian function. This in turn causes a cessation of menstrual function and inhibition of proliferation of sites of endometriosis.
And as the number of drugs that inhibit the secretion of estrogen tough, it is a side effect of osteoporosis - thinning of bone tissue and a tendency to fracture (estrogen prevents osteoporosis). Therefore, GnRH agonists are trying not to appoint a long time.
Conservative treatment of endometriosis is selected individually for each woman.
- treatment of endometriosis