Thrush - a lot of those who have reduced immunity in healthy people as fungi that cause thrush are almost always live in the genital area, without causing the disease. However, overgrown colony of fungi can and should be destroyed, for it produced a special medicines.

Causes of yeast and its main features

Thrush - a disease in which the fungus Candida affects the mucous membranes. In most cases, thrush occurs on the genital mucosa and oral cavity. Candida fungi are natural inhabitants of our mucous membranes, but usually the body's defenses (immune system) prevent their penetration into the human body. If the immune system is reduced, fungi Candida immediately penetrate the mucosa and cause a condition called thrush or candidiasis. Such a decrease in immunity is typical for pregnant women, people who have suffered a serious illness, suffering from some chronic disease with frequent exacerbations undergoing radiotherapy or chemotherapy, which reduce immunity.

A sign of thrush is the appearance of the mucous membranes of the external genitalia of redness, swelling and white raids cheesy consistency. If forcibly remove plaque under it would be a violation of a small surface of the mucous membrane - erosion. The main symptom of thrush - severe itching and a burning sensation in the genital area.

You can confirm the diagnosis of thrush by means of laboratory tests: smear from the genitals found a large number of fungi Candida.

The most modern product for the treatment of thrush - fluconazole

Fluconazole (analogues - Diflucan, fljukostat) - is an antifungal drug that works fine in various pathogenic fungi. When candidiasis it is enough to take only once. Fluconazole ensures that fungal cells can not grow and multiply because of the violation of the permeability of their membranes. And since the vast proliferation of fungi, stop signs, and thrush.

When thrush Fluconazole administered orally once. But it is a compulsory laboratory testing and, if necessary, re-prescribe fluconazole.

Contraindications for use of fluconazole are serious diseases of the kidneys and liver, as well as the idiosyncrasy of the drug, pregnancy, breast-feeding Breast-feeding: feed - and no nails!   baby and child. It is impossible to combine the administration of fluconazole in the intake of alcoholic beverages, as they have a toxic effect on the liver cells and amplify the negative effect on the liver flukonozola.

Fluconazole should not be taken together with certain other medicines. So, it is able to enhance the effect of certain medications, lowering of blood clotting (which is dangerous). There are other medications that better not be used together with fluconazole. Therefore, before it is taking consult your doctor.

Side effect of fluconazole

Fluconazole is generally well tolerated, but sometimes when it is received may experience the following side effects:

• on the part of the gastrointestinal tract: violation of appetite, nausea, bowel disorders (constipation, diarrhea, flatulence), abdominal pain Abdominal pain: Types and Symptoms ;
• Liver: jaundice of the sclera and the skin;
• from the kidney: a violation of their functions;
• with the circulatory system: disturbance of the heart muscle due to the excretion of potassium;
• the central nervous system: fatigue, drowsiness, headache, dizziness, rarely - seizures;
• by Blood: very rarely reduced white blood cell count (decreased immunity) and platelets (bleeding tendency);
• of the skin and its appendages - hair loss;
• allergic reactions of various kinds.

Overdose fluconazole

Overdose fluconazole can cause mental disorders in the form of hallucinations (the patient sees, hears or feels something that really is not), delusions Brad - not only crazy   (there are obsessions of persecution, fear). In such cases, you should immediately call an ambulance. Patients do gastric lavage and hospitalized. At the hospital, patients are administered an intravenous drip fluid, which is then removed from the body using diuretics. Together with the liquid removed from the body decomposition products of fluconazole. If you have taken a very large dose of the drug, sometimes hemodialysis (cleansing of the blood).

Fluconazole - an effective drug for the treatment of thrush Treating Thrush: how to get rid of bad fungus But it is not entirely safe and should be used only on prescription.

Galina Romanenko

  Fljukostat active substance in the form of capsules and suspensions for injection and the solution is fluconazole having antifungal activity. Fluconazole is also part of some other medicines used to treat fungal and yeast infections.

As fljukostat effect on fungi

Flucostat kills fungi that cause infections by acting on their cell membranes. It prevents the development of ergogestrola - an important component of the fungal cells.

Cell membranes are critical for the survival of fungi - they prevent penetration into the cells of unwanted and potentially harmful substances and do not give the contents leak out of cells. Under the influence of fljukostat in cell membranes are formed holes, whereby cells die, and the infection is cured.

Duration of treatment also depends on these factors. For example, vaginal thrush, usually can be cured with a single dose orally adopted; treated in some other infections continues for six to eight weeks. It is important to remember that Flucostat suppresses the development of the fungus, but does not remove the irritation that causes concern.

Which diseases used fljukostat

• Fungal skin diseases such as athlete's foot (tinea Ringworm - not only infectious disease   stop), ringworm Ringworm - how not to be left without hair   (ringworm), tinea cruris, pityriasis (multicolored) zoster, candida infection of the skin
• Candida infections of the mucous membranes of the mouth, throat, lungs and urinary tract
• Candida infections of internal organs and systems, such as the heart, lungs, abdominal organs; systemic candidiasis
• Vaginitis (vaginal thrush, also a Candida infection)
• Candida balanitis or yeast infection in men Thrush in men - not such a rarity   (inflammation of the skin of the penis and foreskin)
• Infections caused by Cryptococcus, e.g., cryptococcal meningitis Meningitis - an inflammation of the meninges And infections affecting the lungs and skin
• Prevention of recurrence of disease caused by Cryptococcus in people with AIDS
• Prevention of fungal infections in people with weakened immune systems and with a reduced level of white blood cells in the blood, for example, as a result of chemotherapy, radiation therapy, or bone marrow transplantation

It is important to get treatment fljukostat to the end, even if you feel better, and you think the infection is cured. Premature termination of drug administration rate can lead to a relapse, and also to the fact that the fungus would be insensitive to the action of the medicament.

Flucostat against thrush

For the treatment of thrush is particularly effective is fluconazole - antifungal agent, the active ingredient fljukostat. Fluconazole, an antifungal agent is a broad-spectrum, effectively neutralizes the activity of fungal microorganisms of the genus candida, yeast pathogens.

Flucostat - the most effective and convenient means for the treatment of different types of yeast, used to inhibit the activity of the fungus Candida is not only on the vaginal mucosa, but also, for example, in the oral cavity, esophagus, intestines, where increased activity of fungal organisms can also cause characteristic symptoms of thrush .  The action fljukostat not dependent on such factors as the method of application - preparation equally effectively acts as while eating, and without it, regardless of the contents of the stomach .  The maximum concentration of the active ingredients of the drug in the body is achieved very quickly - in about one to two hours after ingestion fljukostat, and remains at a high level within seventy-two hours after dosing .  Practically, this means that fljukostat very quickly suppresses basic unpleasant symptoms of thrush - such as itching, burning, cheesy discharge from the vagina - and prevents the re-emergence of .

One of the key advantages fljukostat against thrush - selectivity of antifungal agents: fluconazole, the active ingredient of the drug, neutralizes the activity of fungal organisms, but it does not affect the livelihoods of beneficial bacteria, without breaking, so the microflora of the vagina, and the gastrointestinal tract. In addition, the treatment of thrush fljukostat does not require any additional precautions - at the same time taking fljukostat can continue taking oral contraceptives, use other means of contraception.

As a rule, fljukostat against yeast does not cause serious side effects - in rare cases after taking the drug experience nausea, headache, minor violations of the gastrointestinal tract (dyspepsia). The drug is contraindicated for the treatment of thrush during pregnancy and breastfeeding. In addition, it is not recommended simultaneous reception fljukostat and terfenadine.

Recommended dosage fljukostat against thrush - one capsule a hundred and fifty milligrams of one-time or two capsules of one hundred and fifty milligrams of the first and the fourth day of treatment. In rare cases, if necessary, increase the duration of treatment of thrush, appointed a three-time reception fljukostat - one capsule of the drug on the first, fourth and seventh day of treatment.

Flucostat can be used not only for treatment but also for prevention of yeast in cases where the symptoms keep coming back. The recommended dose for prevention of recurrence of symptoms of thrush - one capsule fljukostat hundred and fifty milligrams once a week for several months.

Drug Interactions

Flucostat can not be taken simultaneously with cisapride and terfenadine.

Under the influence of fljukostat can enhance the action of blood-thinning drugs such as warfarin and nikumalon. As a result, it increases the risk of bleeding, so patients simultaneously receiving anticoagulants and fljukostat must be monitored regularly by a doctor.

The antibiotic rifampicin (used to treat tuberculosis) fljukostat lowers the concentration in the blood. Therefore, those who need to take both drugs, the doctor can consult reception fljukostat in a bit excessive doses.

Furthermore, fljukostat can increase the concentration in the blood (and thus potentiate) the following medications:

• Benzodiazepines, such as midazolam (increasing the concentration of the drug can cause severe sleepiness);
• Cyclosporine;
• Phenytoin;
• Repaglinide;
• Rifabutin;
• Sulfonylurea derivatives used to treat diabetes, such as glibenclamide, glipizide;
• Tacrolimus;
• Theophylline;
• Zidovudine.