When fungal infections of the female genital organs are used vaginal suppositories
Vaginal suppositories - for contraception and treatment of inflammation
livarol bleeding if it is applied usually does not arise, as active substance livarola - ketokonozol hardly enters the bloodstream and has no systemic effects on a woman's body.
Platelets and their role in the human body
Platelets or platelets are small fragments of the disc-shaped cells without nuclei. They are part of the cellular composition of the blood and play a significant role in its coagulation. Platelets are formed from cells of bone marrow megakaryocytes, fall from the bone marrow into the blood and live for five to nine days. The platelets are destroyed by other cells in the spleen and liver.
The main functions of platelets - is the formation of a blood clot that covers the damaged area of a blood vessel, activation of clotting ability of blood plasma and the processes of regeneration of damaged tissues.
Platelets are very sensitive and react quickly to any change in the environment, activating and moving to another state. But more often the cause of platelet activation
Platelets - what they are for the body?
It is bleeding. Activated platelets can adhere to the damaged blood vessel wall, while adhering to each other. Thus is formed a blood clot that covers the damage. Simultaneously, the platelets are involved in blood clotting that occur in its liquid part - plasma.
Reduction of blood platelets is always fraught with bleeding.
Is it possible to bleed when livarole
Vaginal suppositories livarol used for the treatment of vaginal candidiasis
Vaginal candidiasis - Treatment: in the fight against the fungus
- Thrush of female genital mutilation. Active ingredient livarola - ketoconazole has a broad spectrum antifungal activity, including suppresses livelihoods Yeast genus Candida, causing thrush.
Thus ketoconazole it has a number of significant side effects, including reduces blood platelets (a condition called thrombocytopenia) - platelets that accelerate the clotting process. When thrombocytopenia in a patient may receive increased bleeding, which often manifests itself in the form of nasal bleeding.
However, this side effect can only occur when taking drugs, which include ketoconazole, inside. Livarol has no dosage form for oral administration, it is available only in the form of vaginal suppositories, which act locally. Ketoconazole in this case enters the blood in small amounts so that systemic side effects it is simply not counted. So contraindications for use livarola no diseases associated with diminishing of blood clotting.
Why livarol vaginal suppositories during pregnancy should be used with caution?
Nevertheless, the use livarola contraindicated in the first 12 weeks of pregnancy, why? This takes into account the fact that during the first 12 weeks is laying all organs and tissues of the fetus, and even slight toxic effects may interfere with this process, leading to the development of anomalies.
But after the first trimester livarol used to treat pregnant women with caution is recommended. Here it refers to all the side effects of ketoconazole, including its ability to cause thrombocytopenia, since no one knows exactly what the side effects and the extent to which may occur in pregnant women. Side effects ketokonazol pregnant women has not been studied as clinical trials in this patient population is not a reason. Therefore, it is possible, and its influence on the rolling capacity of the blood, which is very dangerous during pregnancy, especially before delivery.
Should we be afraid of bleeding when used livarola?
When applying vaginal suppositories livarol its active ingredient is practically not absorbed into the bloodstream and therefore has no systemic action. Clinical trials livarola not identified any of its systemic effects on the body, including found no occurrences of thrombocytopenia after treatment livarolom
Livarol: cure thrush
. This means that the bleeding in the application can not be livarola
On the contrary, this drug has several advantages. It works very quickly and efficiently, as is injected directly in the inflammation, where the image of its high concentration. Livarola pronounced therapeutic effect combined with minimal side effects, ease of use and short courses of treatment.
The use of vaginal suppositories livarol not accompanied by bleeding.