The mechanism of action tsiprolet

Tsiprolet (INN - ciprofloxacin) refers to a second generation fluoroquinolone, is available in tablets for oral administration. Its mechanism of action is associated with inhibition of the enzyme DNA gyrase of bacteria, which is necessary for the reproduction of bacterial DNA (ie for bacteria).

Tsiprolet kills pathogens (bactericidal effect). It is active against a variety of microorganisms (staphylococci, streptococci, E. coli, etc.). Immune to tsiprolet may be some types of streptococci, mycoplasma, ureaplasma and mushrooms. Tsipolet does not violate the natural intestinal flora. Getting used to the pathogens tsiprolet produced very slowly.

When administered tsiprolet rapidly absorbed in the gastrointestinal tract, one hour with the highest concentration in the blood, well into the organs and tissues. Excreted from the body mainly as unchanged mainly via the kidneys, but some - in the bile and feces.

Indications for use tsiprolet

Tsipolet applied only after determining the sensitivity of pathogen to antibiotics (for seeding of a biological fluid nutrient medium, followed by exposure to these antimicrobial agents). It is used:

• respiratory infections (pharyngitis, bronchitis, pneumonia);
• infections of upper respiratory tract (inflammation of the middle ear, sinuses);
• Eye infections;
• infections of urogenital organs (inflammation of the kidneys and urinary tract, male and female sexual organs), including those with gonorrhea;
• infections of the skin and subcutaneous tissue;
• infections of the musculoskeletal system;
• infections of the digestive system;
• infections of the gallbladder and biliary tract;
• in severe infections, complicated by inflammation of the abdominal cavity and blood poisoning;
• for the prophylaxis and treatment of infections in patients with reduced immunity.

During the reception tsiprolet need to drink for the prevention of the formation of insoluble salts in the kidneys.

Contraindications tsipoleta

Tsiprolet contraindicated:

• if you are hypersensitive to drugs of fluoroquinolones;
• Pregnancy and breast-feeding Breast-feeding: feed - and no nails!   Child;
• children and adolescents;
• patients with epilepsy or other seizure proceeded origin;
• patients with serious diseases of the central nervous system (the state after injury, tumors, etc.).

Tsiprolet elderly patients should be used with caution.

Side effects that occur while taking tsiprolet

Tsiprolet generally well tolerated, but may occur and side effects:

• on the part of the cardiovascular system: palpitations, hot flashes, headaches, such as migraines, fainting;
• the part of the digestive system: loss of appetite, nausea, vomiting, diarrhea, abdominal pain Abdominal pain: Types and Symptoms Bloating;
• the central nervous system: dizziness, headache, fatigue, sleep disturbances Dreams: how to understand our dreams , Agitation, tremors, disturbances in their sensitivity, sweating, loss of coordination, convulsions, anxiety, depressed mood, hallucinations (seeing, hearing, feeling something that really is not), visual disturbances (eg, double objects), noise in the ears, hearing loss;
• on the part of the hemopoietic system: anemia, changes in blood composition, contribute to sensitization of the body, decreased immunity, increased bleeding;
• Allergic reactions: skin rashes, itching, allergic to sunlight, angioedema, bronchoconstriction, volatile joint pain Joint pain - how to understand what is going on? Very rarely - anaphylactic shock and other severe allergic reactions.

Tsiprolet should not be used when performing work associated with increased attention (including while driving a vehicle), since it reduces the ability to concentrate.

Tsiprolet good antimicrobial drug that is manufactured by Indian pharmaceutical "Dr. Reddies Laboratories Ltd".

Basic principles of treatment of giardiasis

In the complex treatment of giardiasis include diet, appointment means improving digestion and its passage through the gastrointestinal tract (choleretic and tyubazh, drugs that restore intestinal microflora, vitamins and trace elements, etc.). All this contributes to the restoration of the gastrointestinal tract and liver. After pre-treatment prescribed drugs that kill giardia.

Pre-restorative treatment

To restore the gastrointestinal tract and facilitate and promote digestion of food on it (together with food removed and Giardia), the following types of treatment.

Diet. From food to be excluded digestible carbohydrates: sweet and baking, flour products, as sugar - a great breeding ground for Giardia. The food is even desirable acidified with acidic juices, fruits and dairy products. It is also recommended to consume more vegetables that are rich in complex carbohydrates (they contribute to the promotion of stool through the intestines). Sweet milk should be excluded during the treatment, as the enzyme deficiency causes giardiasis and milk is not absorbed, but only creates a breeding ground for Giardia.

To improve the digestion of food enzyme preparations are appointed: mezim, festal, Creon Creon - medicine to help digestion   etc.

To remove stagnation of food in the gastrointestinal tract and to ensure its rapid progress, appointed Cholagogue and tyubazh (liberation of the gallbladder from the stagnant bile by taking Cholagogue and expansion of the biliary tract with the help of heat): bile promotes rapid digestion of food in 12 -perstnoy intestine and promote it on the intestines, in addition, bile suppress the vital activity of Giardia.

To improve colon appointed probiotics (preparations containing bacteria promoting intestinal normal operation, such as bifidobacteria and lactobacilli), prebiotics (preparations containing substances necessary for the reproduction of the normal microflora of the intestine), vitamins and minerals that are part of the intestinal enzymes involved in the digestion of food. Improvement of the colon contributes to the further promotion of food and removal of Giardia with it.

Rapid elimination from the intestine lamblia can be achieved with the help of drugs, which accumulate on the surface of bacteria, protozoa, and toxins are eliminated from the body. These drugs are called entnerosorbentami (polisorb, Polyphepanum, smectite Smecta - necessary in any medicine cabinet   and so on).

Treatment with drugs that kill giardia

After the gastrointestinal tract is prepared for the complete expulsion of Giardia, prescribers who kill them. It metronidazole Metronidazole - what is it?   (Trichopolum), tinidazole, furazolidone Furazolidone - contributes to the death of bacteria , Makmiror and some other preparations. Repeat the treatment in 7-10 days. Be sure to conduct laboratory examination of feces to identify lamblia cysts. In addition, the patient talk about ways to re self and teach personal hygiene.

If there is a long period for giardiasis, it is necessary to consult immunologist to exclude immunity disorders and their correction.

Prevention of giardiasis - a personal hygiene and the elimination of hotbeds of giardiasis (eg, in kindergartens). If we stick to the rules of hygiene, it is something of giardiasis can be removed without treatment.