Prednisolone tablets are usually prescribed for chronic diseases, including chronic infectious and inflammatory, allergic, autoimmune (caused by an allergy to the body's own tissues) and degenerative processes in various organs and tissues.

How does prednisone tablets

Prednisolone is available in tablets of 1 mg and 5 mg. When receiving prednisolone tablets into rapidly absorbed from the gastrointestinal (GI) tract into the blood and there is associated primarily with the proteins. With a decrease in blood plasma protein possible toxic effects on the body unbound prednisolone. Action prednisolone begins 90 minutes after the administration, tablets and continued for 18-36 hours. Then it decomposes mainly in the liver and excreted in the urine and feces.

Prednisolone has a pronounced anti-inflammatory, anti-allergic, anti, protivoekssudativnoe action, relieves itching and pain caused by inflammation and allergies. It also inhibits the growth of connective tissue cells and tumor cells, suppresses the immune processes. Prednisone tablets can prevent or quickly remove the breathing disorder while angioedema (angioedema).

Tablets prednisolone has overall systemic exposure to the organism, which is characterized by high efficiency in combination with more side effects.

Which diseases are appointed pill prednisolone

Prednisolone tablets are appointed only after a preliminary examination and exclusion of contraindications to their use. The dose of prednisolone and duration of treatment is usually chosen by the doctor individually.

Tablets prednisone is prescribed for chronic long flowing inflammatory processes in the joints and spine, which are accompanied by severe pain. First of all, it is chronic arthritis. But as inflammation is almost always caused by infectious factors (even if it is not possible to confirm the laboratory) tablets of prednisolone in this case, appointed under the protection of antibiotics that suppress infectious processes. Courses of treatment with prednisolone is usually assigned shorter, just to relieve the main symptoms of inflammation and pain.

Sometimes prednisolone tablets prescribed for the treatment of chronic allergic diseases such as bronchial asthma, chronic rhinitis, allergic skin diseases (atopic dermatitis, eczema, atopic dermatitis). In these cases, prednisone also try to assign short courses.

In diseases, which are based on allergic to their own tissue (eg, rheumatoid arthritis, glomerulonephritis and others), prednisone relieves patients taking symptoms such as pain and swelling of joints, change in renal function, and so on.

It helps treatment with prednisolone inwards in systemic connective tissue diseases such as scleroderma and lupus erythematosus - it reduces the progression of these diseases. In rheumatoid arthritis it prevents the development of heart diseases.

The ability to suppress the growth of tissues of prednisolone used in the treatment of cancer.

As a replacement therapy pills prednisone is prescribed for disorders of the adrenal glands. In this case, prednisolone Prednisolone - against inflammation, allergy and pain, but with complications   prescribe long.

Contraindications

The tablets of prednisolone should not be used if you are hypersensitive to it, feeding baby Breastfeeding - a personal choice   breast, gastric ulcer and duodenal ulcer, hypertension, glaucoma, diabetes, osteoporosis, thrombophlebitis, severe endocrine disease (Cushing), untreated infectious process (bacterial, viral or fungal), psychosis and depression, diseases, developed on Background vaccinations (especially vaccination against tuberculosis), as well as for two weeks before and after vaccination.

In pregnancy, prednisolone tablets are used only when absolutely necessary in the case where the intended benefits to the mother's body exceeds the possible negative effects on the fetus.

Side effect

Side effects of prednisone tablets usually occur after prolonged use at high doses. This may cause erosive and ulcerative lesions of the stomach and duodenum, a persistent increase in blood pressure, thrombosis, osteoporosis, worsening of diseases such as glaucoma Glaucoma - a perspective possible blindness   and diabetes Diabetes - threatening and incurable disease . It is also possible spread of infections of bacterial, viral or fungal origin.

Prolonged use of prednisolone tablets occurs persistent suppression of adrenocortical function, leading to their failure over time and the formation of Cushing's syndrome. There may also menstrual irregularities and infertility in women and impotence in men. The increased excretion of potassium from the body can lead to the development of cardiovascular disease. In children, growth may be disrupted.

Galina Romanenko

Tinidazole - is an antibiotic drug. Admission tinidazole recommended for disorders such as trichomoniasis, giardiasis, amoebiasis, bacterial vaginosis Bacterial vaginosis - sex is not recommended , Vulvovaginitis Vulvovaginitis - a disease of children and the elderly .

Side effects

In very rare cases, tinidazole causes severe allergic reactions. When symptoms such as skin rash, shortness of breath, swelling of the face, lips, tongue or throat, you should immediately seek medical help.

Other side effects of tinidazole can be:

• Convulsions;
• Fever, chills, muscle aches, and other symptoms similar to flu symptoms;
• Numbness, tingling or burning sensation on the skin;
• Fever, sore throat and headache;
• The appearance of bubbles on the skin and / or heavy peeling.

Those who have symptoms such as should consult a doctor without delay.

Much more common less serious side effects of mononucleosis, for example:

• Vaginal yeast infection (characterized by white discharge and itching);
• An unpleasant metallic taste in the mouth;
• Nausea, vomiting, loss of appetite, indigestion;
• Constipation, diarrhea, stomach cramps;
• Unusually dark urine;
• Headache, dizziness, Dizziness - if the ground is slipping from under his feet ;
• Pain in muscles and joints;
• Dry mouth, thirst, change in the color of the tongue;
• White patches or sores in the mouth or on the lips;
• A minor skin rash or itching.

Safety measures

Before taking tinidazole, tell your doctor if you have ever had an allergic reaction to this drug, and / or metronidazole, or if you are allergic to any other medicines. Furthermore, tinidazole may not be recommended for various blood problems (e.g., low white blood cell count), disorders associated with the operation of the brain or nervous system, liver and kidney.

During the reception, tinidazole and for at least three days after the end of treatment should refrain from drinking alcohol.

Dosage regimen

Trichomoniasis 2 g tinidazole orally once a day, with food. Since trizomoniaz is sexually transmitted, it is necessary the simultaneous treatment of both partners.

Giardiasis: Adults - 2 g tinidazole a day with meals. For children over three years - a dose of 50 mg per 1 kg body weight (but not more than 2 g) once a day with meals.

Bacterial vaginosis: Non-pregnant women - 2 g of the drug orally once a day for two days or 1 g orally once a day for five days. Security tinidazole for pregnant women has not been proved.

Amoebiasis:

• Intestinal amebiasis: Adults - 2 g tinidazole, with meals, once a day for three days. The dosage for children is calculated by the formula 50 mg per 1 kg of body weight; treatment lasts three days.
• Tropical abscess Abscess - why it is so dangerous ulcers?   liver: adults - 2 grams per day, with food, for three to five days. Babies - one dose per day at the rate of 50 mg per 1 kg of body weight for three to five days.