Fungal meningitis is not as common as bacterial or viral. However, this disease is quite common and can be severe. Fungal meningitis occurs mainly in subacute or chronic and is accompanied by a high mortality rate. But there are also keen for fungal meningitis.
Fungal meningitis - Causes of disease
Fungal meningitis can be caused by many fungi, but most often it is the cause of Cryptococcus, coccidia and candida (yeast fungi genus Candida). Due to these causes of meningitis are as common symptoms, as well as its own characteristics, which should pay attention.
The prognosis of fungal meningitis is always very serious, as the treatment of fungal infections - is always a problem.
Blastomikozny meningitis develops against the background of cryptococcosis (European blastomycosis) - a disease caused by yeast fungi Cryptococcus. Cryptococcosis is a severe systemic deep fungal disease of humans and animals, mainly affecting the lungs, central nervous system, skin and subcutaneous tissue and then spread the infection to the internal organs. Sources of infection for humans and the spread of infection are currently unknown.
Symptoms of meningitis blastomikoznogo develop gradually, often showing signs of encephalitis (brain tissue damage) in the form of convulsions and lesions of the cranial nerves. Often develop small seizures of epilepsy Jackson type. At the same time against the clear consciousness of having spasms in some muscle or group of muscles limbs (usually the hand), or muscles of the face, followed by the spread of seizures on the same side limbs or facial muscles. Sometimes the cramps spread to the opposite side, and in some cases become generalized (common) character.
The disease resembles tuberculous meningitis
TB meningitis - the consequences of the spread of the pathogen
. Cerebrospinal fluid pressure is increased, it detected a large number of blood cells with a predominance of lymphocytes. The diagnosis is detection of the pathogen.
Treatment blastomikoznogo meningitis is antifungal agents, mainly amphotericin B (it is administered intravenously and into the spinal canal) in combination with antikriptokokkovoy rabbit serum or gamma globulin.
Coccidioidomycosis (California fever) - a disease that is caused by filamentous yeasts coccidia. Coccidioidomycosis is manifested in the form of primary pulmonary infection, progressive granulomatous lesions of the skin, bones, joints, internal organs and the meninges. They get sick, not only people but also animals - rodents, dogs, cattle. The pathogen is the soil from which the spores enter the body by inhalation of dust. The pathogen can also be transmitted from person to person and from animal to person through close contact.
The disease begins in an average of two weeks after infection, and flows initially in the form of a cold or pneumonia with skin lesions in the form of nodular or exudative erythema multiforme.
Inflammation in the lining of the brain characterized by the formation of multiple small nodules in the process often involved with the substance of the brain - is developed meningoencephalitis. The disease chronic, lasting for several months, the prognosis is poor.
Treatment is carried out as amphotericin B.
Candida meningitis - because of fungal meningitis is the most common. Called it the yeast of the genus Candida, and often develops in the lungs or kidneys candidiasis. In the meninges formed infiltrates from blood cells, and the epithelium, followed by hemorrhage necrosis (tissue necrosis). Often defeat of the meninges proceeds to brain tissue, where they form small abscesses.
There are diffuse meningitis
Meningitis - an inflammation of the meninges
, Basal meningitis (preferentially localized on the lower surface of the brain) and meningoencephalitis. Symptoms resemble Candida meningitis tuberculous meningitis or abscess
Abscess - why it is so dangerous ulcers?
Diagnosis is based on detection of the infectious agent in cerebrospinal fluid. Treatment of vulvovaginal meningitis carried antifungal drugs, including amphotericin B and fluconazole
Fluconazole - used with caution
Fungal meningitis - this is a very dangerous disease and its prognosis depends largely on how quickly the patient will be prescribed appropriate treatment.